It highlights the fascinating intertwined nature of developmental and ageing-related pathways.
Thanks to #impetusgrants #hevolution [2/2]
#CpG #ucCpGs #epigenomics #DNAmethylation #ageing #aging #populationgenetics @qmulepigenetics.bsky.social sky.social
doi.org/10.64898/202...

BioRxiv preprint from us identifying ultra-conserved Human CpG Dinucleotides - the crucial motif for DNA methylation in differentiated cells - from >0.5 million whole genome sequences (UKB/gnomAD).
This identified enriched signals in developmental, ageing-related, & brain-expressed genes. [1/2]

'HAQER CpG Beacons' in Human-specific Cortical Development #Epigenomics #HumanEvolution

Together with Chris Bell and Alexander Dawson, we are recruiting an PhD student (LIDo iCASE) at @qmulepigenetics.bsky.social to work on using long read nanopore technology to investigate DNA methylation on native DNA. This is a joint project with ONT. www.findaphd.com/phds/project...

Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging Glaucoma is a major cause of blindness globally and its prevalence rises with age. This study explored systemic blood-derived DNA methylation epigenetic biomarkers for association with glaucoma and...

DNA methylation biomarker study (EWAS, EpiScores, & DNAm clocks) for Glaucoma & IOP just published in Epigenetics #Epigenomics #Glaucoma #DNAmethylation #EpigeneticClocks
@qmulepigenetics.bsky.social doi.org/10.1080/1559...

Review from us just out on the utility of DNA methylome assessment in health and disease. #Epigenomics #DNAmethylation @qmulepigenetics.bsky.social
www.tandfonline.com/doi/epdf/10....

Only a couple of months left until our official QMUL Centre for Epigenetics Launch Conference! We will have an amazing list of guest speakers, including Michelle Percharde @mpercharde.bsky.social from MRC LMS, UK. Spaces are limited.

QMUL Centre for Epigenetics Launch Conference 2025 Join us in celebrating becoming an official Centre for Epigenetics at QMUL!

We're excited to announce the official QMUL Centre for Epigenetics Launch Conference 2025! 🎉 To find out more and book your free ticket, please follow the link below:
www.eventbrite.co.uk/e/qmul-centr...

@qmul.ac.uk

@bartscharity.bsky.social

@qmulepigenetics.bsky.social

QMUL Epigenetics Centre (www.qmul.ac.uk/epigenetics/) is looking to recruit a senior lecturer with expertise in Genomics/Epigenomics and/or cell-free DNA. This is an excellent opportunity to join a strong Epigenetics and genomics community. Pl share/apply here
qmul-jobs.tal.net/vx/mobile-0/...

Advancing early disease detection With our funding researchers at Queen Mary will investigate how the marks on DNA in our blood can be used to detect a wider range of diseases than at present.

We'll be leveraging the expertise at @qmulepigenetics.bsky.social to develop liquid biopsy-based diagnostics to serve our ethnically diverse population. Co-led by Gabriella Ficz, Christopher Bell, Stamatina Iliodromoti and Ajay Sinha. Amazing support from Barts Charity.