New paper from the Hachisuka / Todd / Bell labs, out in @elife.bsky.social: Characterisation of cold-selective lamina I spinal projection neurons doi.org/10.7554/eLif...

A molecular map of the human spinal dorsal and ventral horn defines arrangement of neuronal types and glial sex differences The spinal cord is the gateway for sensory information from the body as it ascends to the brain, as well as a major motor output center of the nervous system. It is also a key location for sensory-mot...

Thrilled to share our latest preprint using single nuq sequencing and Xenium to define neuron organisation and sex differences in glia within human spinal cord. Truly a collaborative effort, with a big shoutout to Katherin Gabriel and @tedpricethepainguy.bsky.social

www.biorxiv.org/content/10.1...

The GIF shows GCaMP6s-labelled sensory neurons exhibiting spontaneous activity (visible as flickering) in a model of pain.

Characterisation of cold-selective lamina I spinal projection neurons Skin cooling is detected by primary afferents that express the Trpm8 channel, but how this information is conveyed to the brain remains poorly understood. We have previously identified a population of...

New preprint out now!
www.biorxiv.org/content/10.1...

Are you interested in omics approaches to pain and projection neurons? Why not join us? We’ve got a post-doc position available. Happy to discuss further with anyone who is interested. www.jobs.gla.ac.uk/job/research...
#neuroskyence #neurosci #PainResearch

It was a joy to share how the different lab at the @spinalcordgroup.bsky.social investigate sensory processing and neural circuits.

This project has grown from a concept into a real educational tool—and seeing people engage with it has been the most rewarding part! #SciOutreach #STEMeducation

Each sensor responds to a specific input—like pressure or temperature—and converts it into an electrical signal that travels to the brain. 🧩⚙️

We showcased the board at the @glascifest.bsky.social , where it sparked curiosity and great conversations with audience of all ages.

We are excited to share an outreach project from MVLS’s @spinalcordgroup.bsky.social, @weirlab.bsky.social and @davehughesgla.bsky.social lab, in collaboration with @mhassan9.bsky.social and Mahmoud Wagih from @uofgengineering.bsky.social.

#EngineeringInMedicine #ScienceCommunication

Macrophages amplify the spontaneous activity of damaged sensory neurons in a human co-culture model of neuropathic pain Neuropathic pain is a highly prevalent condition for which treatments are hampered by low efficacy and dose-limiting side-effects. Injury to the somatosensory nervous system causes maladaptive plastic...

New preprint out now describing how macrophages can amplify spontaneous activity of damaged sensory neurons in a humanised in vitro model www.biorxiv.org/content/10.1...

Members of the Spinal Cord Group have been busy at the Glasgow Science Festival today at the Glasgow Botanics

The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events www.biorxiv.org/content/10.1101/2025.05....

Expression of Tacr1 and Gpr83 by spinal projection neurons Anterolateral system (ALS) projection neurons underlie perception of pain, itch and skin temperature. These cells are heterogeneous, and there have therefore been many attempts to define functional po...

New preprint from the Todd / Bell labs now on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1...

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Come join our lab as Postdoctoral Fellow! The project will investigate the maturation of spinal circuits and their plasticity within chronic widespread pain states.
Apply here: www.ucl.ac.uk/work-at-ucl/... until 11th April.
@ucllifesciences.bsky.social @uclnpp.bsky.social @jobrxiv.bsky.social

bss-neuropain.u-bordeaux.fr/en/

📢 Join us for the next European Pain School!

🗓️ 7–13 June 2025

📍 Certosa di Pontignano, Siena – a stunning setting for cutting-edge learning.

📝 Apply by: 28 February 2025 eps2025.azuleon.org/application

💡 This year’s focus: Cancer Pain Research, featuring topics like:

Human sensory neuron and macrophage co-culture; developing a model to test agents capable of disrupting painful neuroimmune signalling at University of Glasgow on FindAPhD.com PhD Project - Human sensory neuron and macrophage co-culture; developing a model to test agents capable of disrupting painful neuroimmune signalling at University of Glasgow, listed on FindAPhD.com

All undergraduate/Master's students interested in #PainResearch #PainScience #ImmunoSky: here is a fully-funded PhD opportunity at the brilliant @uofglasgow.bsky.social
www.findaphd.com/phds/project...

Human sensory neuron and macrophage co-culture; developing a model to test agents capable of disrupting painful neuroimmune signalling at University of Glasgow on FindAPhD.com PhD Project - Human sensory neuron and macrophage co-culture; developing a model to test agents capable of disrupting painful neuroimmune signalling at University of Glasgow, listed on FindAPhD.com

Anyone interested in a PhD in pain research, we have a fully-funded position available in the Weir lab.
www.findaphd.com/phds/project...