Happy to share our work on RPA exhaustion activating SLFN11 published in @natcellbio.nature.com today!
Posts by Alex Pike
Proteins are dynamic structures, but structural biology often shows them as static snapshots. Inspired by long-exposure photography and generative art, I built ProteinCHAOS, an artistic tool inspired by molecular dynamics to capture protein flexibility over time, much like long-exposure images.
my amazement with the technology surpasses my annoyance with my past self for not sequencing this plasmid sooner, since my original map has lots of issues
Gotta take time to appreciate the small joys in life, like samples getting delivered at 8:30am to @plasmidsaurus.bsky.social and results getting emailed to you right at noon!
Our department is hiring a conservation ecologist!
See the job posting here & please share:
jobs.oberlin.edu/postings/16671
In #GENETICS, Grace Duke and Robert V. Skibbens report on novel gene deletion combinations with implications in cohesion activities and show their requirements in #yeast cell cycle progression and cell viability.
Read more: buff.ly/Fa2FAfQ
Grad student Gayathri Muthukumar investigates how the outer mitochondrial membrane (OMM), a hub for signaling proteins, helps regulate mitochondrial function. Her research aims to uncover how changes in the OMM’s protein makeup can fine-tune the behavior of individual mitochondria. #Sciencein60
Crick researchers have shown that the ‘pacemaker’ controlling yeast cell division is located inside the nucleus, rather than outside it as was previously thought.
This research was led by @nitinkapadia.bsky.social and Paul Nurse.
www.crick.ac.uk/news/2025-06...
Hopped onto the tenure track today! What were your favorite purchases when you started your lab? We're doing genetics and biochemistry in yeast 🧬
Postdoc positions open in my lab (Francis Crick Institute) to study
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
Breaking news: The National Institutes of Health has ceased terminating grants on politically sensitive topics after a federal judge ruled last week that the cancellations were illegal.
scim.ag/4l9MO8Y
Especially in file names
Please, mentees, I am begging you
The NIH has said it will implement a "new award stucture" by October.
But researchers say it is absolutely senseless and reckless to cut off funding without an alternative in place.
I spoke to nine affected researchers.
This is their story.
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Re-upping this: I curated a YouTube playlist on molecular biology. I use it to train undergrads and new grad students. I usually have them watch the playlist first before showing them how to do in the lab.
www.youtube.com/playlist?lis...
This framing is all wrong
Our international students are not a “crucial funding source”
They are our STUDENTS
They are the reason we EXIST
We teach STUDENTS
Harvard today, your institution tomorrow.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
definitely worth checking surplus lab equipment vendors — some items are barely used or even brand new — as a way of getting around the tariffs
an exciting time to receive your start-up funds 💸
Wow.
We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international)
We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc.
Download this massive database here for free: research.jhu.edu/rdt/funding-...
Excited to be jumping onto the tenure track at Oberlin after a couple of years as a visiting prof!! www.oberlin.edu/news/oberlin...
“In essence, the EPA is proposing to roll back the clock on environmental protection and allow industry to release tons more toxic pollutants into the air we breathe,” Gillian C. Goobie, MD, PhD.
Read more about the impact of the EPA’s announcement to reconsider over 30 EPA regulations:
Our top health official thinks castor oil cures measles, while his bosses cut funds to much of the most important medical research in the world.
The toll in disease and death is beyond our ability to imagine.
And the goddamned eggs still cost $9 a dozen.
Gift link: www.wsj.com/health/healt...
Many of these grants are fellowships and training grants supporting smart young people interested in bettering the world through their research. It is sad to see NIH funding used as an indiscriminate tool of retribution.
In #NextGenSequencing news, China now outright bans the imports of Illumina $ILMN machines in US Retaliation. www.bloomberg.com/news/article...
Every news outlet reporting Elon Musk's comment about accidentally canceling Ebola prevention efforts and quickly restoring them should also say they haven't been restored, they're still canceled, the outbreak-fighting teams are dismantled, the money is gone
www.washingtonpost.com/politics/202...
More NIH intramural news...
As part of the new Executive Order IMPLEMENTING THE PRESIDENT'S "DEPARTMENT OF GOVERNMENT EFFICIENCY" COST EFFICIENCY INITIATIVE, NIH staff are advised not to use their NIH Purchasing Cards.
If this get any more efficient, they will not be able to so anything...