Thanks for promoting (and accepting!) this was a slow paper because midway through we got the “negative” in vivo result that made us question our whole model
… but we persisted and found an interesting species difference
Inflammatory signaling differentially changes #chromatin accessibility and #gene expression of the PD-associated kinase #LRRK2 between human and mice
Alexandra Beilina, Jae-Hyeon Park, Natalie Landeck...Mark R. Cookson @markrcookson.bsky.social #Parkinsons
link.springer.com/article/10.1...
In @jcb.org, @lysoluis.bsky.social, @markrcookson.bsky.social et al. show how two distinct pRAB effectors and RHD members, JIP4 and RILPL1, provide antagonistic motor force to regulate #lysosome tubulation. rupress.org/jcb/article/...
I heard Norway is recruiting “top” researchers to leave some countries and join them. Yet I have not had a call. Hallo?
Funny I have the same followers but study different things. They must be planning a grant together to work on the intersection of inflammation and neurodegenerative disease
This is a sign of how upside down the constitutional order is right now. The President is supposed to ask Congress for money, not the other way around! #mepolitics
I don't really have words for how devastating it would be to lose the entire intramural program. This has to be stopped.
Just astonishing.
"Memoli had no choice, he insisted: He was following the direction of three HHS officials—Dorothy Fink, then the acting secretary; Heather Flick Melanson, chief of staff; and Hannah Anderson, deputy chief of staff of policy—who told him, in no uncertain terms, that the pause was to continue..."
/1
In a not-so-dystopian future, glum-looking Oompa Loompas working at a sad Willy's Chocolate Laboratory will be the picture of science being made in the U.S.. .. Sad just like the experience in Glasgow.
The future of science in the U.S. is looking so promising.
Now is the moment to do more, not less, in the fight against Alzheimer's. (Alzheimer's Impact Movement logo)
Ensure the voices of people living with dementia and their caregivers are heard. Urge your members of Congress to reaffirm their commitment to the Alzheimer’s community today. We’ve made great progress and we cannot afford to stop now. bit.ly/alzaction
I was part of the Marzi lab for my masters, PhD, and now postdoc. @sj-marzi.bsky.social is an enthusiastic scientist and supportive mentor. The science is cool and the people are even cooler. Can’t recommend enough!!! 🤓
Apply apply apply 👇🏻
Hear what you want to hear
I’ve long wanted a BS meter outside the office but it would always be at zero … plus yeah HR
That should be zero
What fresh hell is this? Have a tea bag of reasonable repute in my hotel room but it’s decaffeinated? What use will this be tomorrow am???
A two-month-old has died from pertussis in Queensland, Australia. Like many countries including the US, Australia is in the midst of a pertussis epidemic. In Queensland, uptake of maternal pertussis vaccination & infant vaccinations have declined. Lower rates of both put the youngest at risk.
So this would come under ad hominem attacks. Credit to @michelerosenthal.com
Can you figure out how many publications came from this funding?
useful rubric for those of us who love logic from @michelerosenthal.com
Just in case this comes in handy in the next, say, few years or so
Hey @mahoneykc.bsky.social more evolutionary information for you
In remembrance of those lost to COVID-19, I created a Spotify playlist featuring songs by musicians who passed away from the disease: open.spotify.com/playlist/6jE.... So much beautiful humanity gone.
Welcome
Scary, sorry. As for the scanning for DEI, I worry we'll all be subject to that soon enough. Sad.
Confirm
Patrick Stewart on behalf of many other old white men
Oh I'm sure this is all socialization
