"Nonoptimal Temperature and Cardiovascular Health: A Scientific Statement From the American Heart Association."
Publié ce jour dans Circulation.
#MedSky #CardioSky @ahajournals.bsky.social
www.ahajournals.org/doi/full/10....
Clinical characteristics of primary sclerosing cholangitis. (A) The disease affects the biliary tree through inflammation and fibrosis, which results in multifocal biliary strictures and a high risk of cholangiocarcinoma. (B) When the disease progresses, high-grade strictures, often with prestenotic dilatation, can develop, leading to biliary obstruction and clinical symptoms. (C) Fatigue, itching, jaundice, bacterial cholangitis, and intermittent or persistent right upper-quadrant abdominal pain are common symptoms and signs in primary sclerosing cholangitis. Primary sclerosing cholangitis is associated with inflammatory bowel disease and 50–80% of affected individuals have concomitant inflammatory bowel disease. Primary sclerosing cholangitis inflammatory bowel disease shows distinct features from classic isolated inflammatory bowel disease, often with extensive colitis, a patchy inflammatory distribution that shows dominance of inflammation in the ascending colon, rectal sparing, and an increased risk of colorectal dysplasia compared with colitis without primary sclerosing cholangitis. (D) The inflammation almost always involves the colon and isolated ileal disease is rare. Reproduced with permission from Kari C Toverud.
Primary sclerosing cholangitis is a rare liver disease, characterised by biliary inflammation and fibrosis.
A Seminar explores the clinical features, pathogenesis, and challenges and opportunities in managing the disease: spkl.io/63323A4P8d
"Accuracy of glomerular filtration rate estimation based on creatinine and cystatin C for monitoring moderate chronic kidney disease in adults: prospective, longitudinal cohort study."
Publié ce jour dans @bmj.com.
#MedSky #NephSky
www.bmj.com/content/392/...
"Asundexian for Secondary Stroke Prevention."
Publié ce jour dans le @nejm.org.
#MdSky #NeuroSky
www.nejm.org/doi/full/10....
"AGA Clinical Practice Update on Management of Gastric Polyps: Expert Review."
Publié en avril dans Clinical Gastroenterology and Hepatology.
#MedSky #GastroSky
www.cghjournal.org/article/S154...
"Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026."
Publié en avril dans Critical Care Medicine.
#MedSky
journals.lww.com/ccmjournal/f...
"Clinical Care for Patients With Elevated Lipoprotein(a) Level in Canada: A Practical Framework for Screening, Risk Assessment, and Management."
Publié en avril dans Canadian Journal of Cardiology.
#MedSky #CardioSky
onlinecjc.ca/article/S082...
"Risk of Heart Failure Hospitalization for GLP-1 Receptor Agonists Versus DPP-4 Inhibitors or SGLT-2 Inhibitors in Patients With Type 2 Diabetes: A Target Trial Emulation."
Publié ce jour dans Circulation.
#MedSky #CardioSky @ahajournals.bsky.social www.ahajournals.org/doi/full/10....
“Projected estimates of cancer in Canada in 2026.”
Publié ce jour dans @cmaj.ca.
#MedSky
@cmadocs.bsky.social
www.cmaj.ca/content/198/...
"Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: 10-year follow-up of the HOST-EXAM trial."
Publié ce jour dans @thelancet.com.
#MedSky #CardioSky
www.thelancet.com/journals/lan...
"Prevalence of liver fibrosis in the general population (the LiverScreen project): a multinational European cohort study."
Publié ce jour dans @thelancet.com
#MedSky #LiverSky
www.thelancet.com/journals/lan...
"Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial."
Publié ce jour dans @thelancet.com.
#MedSky
www.thelancet.com/journals/lan...
Original Article | APR 9, 2026 Multifaceted Strategies for Hypertension Control in Low-Income Patients (IMPACTS-BP) Figure 2A. Change in Systolic Blood Pressure over 18 Months.
Among low-income patients with hypertension, a multifaceted, team-based strategy resulted in a greater reduction in systolic blood pressure than enhanced usual care. Full IMPACTS-BP trial results: nej.md/4cuvnhA
Editorial: Systems-Based Success for Hypertension nej.md/4sg9ibe
#Cardiology
“Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease.”
Étude Ez-PAVE.
Publié ce jour dans le @nejm.org.
#MedSky #EndoSky #ACC26
www.nejm.org/doi/full/10....
"AASLD IDSA Practice Guideline on treatment of chronic hepatitis B."
Publié en avril dans Hepatology.
#MedSky #LiverSky
journals.lww.com/hep/fulltext...
“Tenecteplase for Acute Non–Large Vessel Occlusion 4.5 to 24 Hours After Ischemic Stroke Onset.”
Publié ce jour dans @jama.com.
#MedSky #NeuroSky
jamanetwork.com/journals/jam...
"Inflammation and Cardiovascular Disease: 2025 ACC Scientific Statement: A Report of the American College of Cardiology."
Publié en mars dans J Am Coll Cardiol.
#MedSky #CardioSky @accintouch.bsky.social
www.jacc.org/doi/10.1016/...
“Percutaneous coronary intervention versus coronary artery bypass grafting for unprotected left main stenosis: 10-year final results from the randomised, open-label, non-inferiority NOBLE trial.”
Publié ce jour dans @thelancet.com.
#MedSky #CardioSky
www.thelancet.com/journals/lan...
"Combat contre la mort."
Par Edvard Munch (1915)
🚨 #NephJC short 🩳from @kidneyboy.bsky.social
The PUSH trial!
😉Can a wink, a nudge & a push encourage kidney stone formers to drink more fluid to prevent recurrence 🪨?
(Hint: have 💦 behavioral trials worked in CHF or PCKD?)
#NephSky #MedSky
www.nephjc.com/news/2026/4/2/nephjc-short-the-push-trial
“Discontinuation of Beta-Blocker Therapy after Myocardial Infarction.”
Publié ce jour dans le @nejm.org.
#MedSky #CardioSky
www.nejm.org/doi/full/10....
"Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation."
Publié ce jour dans le @nejm.org.
#MedSky #CardioSky
www.nejm.org/doi/full/10....
Le prochain balado de BaladoCritique : club de lecture médical portera sur l'essai clinique COBRRA, publié dans le
@nejm.org, sur le traitement anticoagulant dans la maladie thromboembolique.
Enregistrement à venir le 22 avril prochain.
À suivre !
#EBM @asmiq.bsky.social @revmedinterne.bsky.social
"Environmental Stressors and Cardiovascular Health: Acting Locally for Global Impact in a Changing World: A Statement of the European Society of Cardiology, the American College of Cardiology, the American Heart Association, and the World Heart Federation."
www.jacc.org/doi/10.1016/...
"2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines."
www.ahajournals.org/doi/full/10....
"American Society of Hematology 2025 guidelines for treating newly diagnosed acute myeloid leukemia in older adults."
Publié en mars dans Blood Advances.
#MedSky #HemSky
ashpublications.org/bloodadvance...
"Surveillance par imagerie d’une dilatation dégénérative de l’aorte ascendante chez l’adulte."
Publié en mars par @inesss.qc.ca.
#MedSky #CardioSky
Réf : www.inesss.qc.ca/publications...
#519 Mild Autonomous Cortisol Secretion: Exploring Uncharted Waters 🌊🧭
Adrenal incidentaloma? 👀 Don’t miss what could be hiding beneath the surface…
Level up your approach to cortisol 📈learn how to recognize & manage mild autonomous cortisol secretion (MACS) @irinabancos.bsky.social
Notre article-résumé sur l'essai clinique CREST-2 est maintenant publié dans @revmedinterne.bsky.social.
Bonne lecture !
#MedSky #NeuroSky #CardioSky #EBM
@asmiq.bsky.social @usherbrooke.bsky.social
www.sciencedirect.com/science/arti...
