The May issue of @lancetgastrohep.bsky.social is out now at www.thelancet.com/gastrohep!

Content this month includes #colorectalsurgery, #colorectalcancer, #viralhepatitis + more

#GastroSky #MedSky #LiverSky #HepSky

For a patient with acute liver failure on a background of alcohol-associated cirrhosis, would you recommend liver transplantation or continue medical intensive care management alone? Vote on the best option: nej.md/4c3hjuh

#MedSky #Surgery #GastroSky

Adding RFA to chemotherapy fails to boost survival for locally advanced pancreatic cancer Radiofrequency ablation does not improve overall survival for patients with locally advanced pancreatic cancer who are undergoing chemotherapy and is associated with poorer quality of life.

#MedNews - Radiofrequency ablation does not improve overall survival for patients with locally advanced #PancreaticCancer who are undergoing chemotherapy and is associated with poorer quality of life.

👉 buff.ly/pJPGaeb

#GastroSky #OncSky

Distinct phenotype of primary sclerosing cholangitis-associated inflammatory bowel disease Emerging data support the concept that PSC-associated IBD be viewed as a distinct colitis phenotype that is pathophysiologically linked to PSC rather than as a subtype of ulcerative colitis.

Emerging data support the concept that primary sclerosing #cholangitis-associated #IBD be viewed as a distinct colitis phenotype that is pathophysiologically linked to PSC rather than as a subtype of ulcerative colitis.

👉 buff.ly/aXKcYuO

#GastroSky

Impact of IBS on Older Adults: A Narrative and Systematic Review of Diagnostics, Quality of Life Considerations, and Therapies Including Pharmacologic and Non-Pharmacologic IBS can significantly impact older adults, but what do we know about the effect of age-related changes on the diagnosis and treatment of IBS in older adults compared with their younger counterparts?

#IBS can significantly impact older adults, but what do we know about the effect of age-related changes on the diagnosis and treatment of IBS in older adults compared with their younger counterparts?

👉 buff.ly/J2s577K

#GastroSky #GeriatricMed

2/2. The probiotics that do make it through the stomach stay with us only temporarily, but do not colonize. So how did we get some colonized in the beginning of life?
#Medsky
#Gastrosky
#Nutrition
#Microbiome
#Aging
#Longevity
#BrainGutAxis

Robot-assisted versus conventional minimally invasive oesophagectomy for oesophageal squamous cell carcinoma (RAMIE): a multicentre, open-label, randomised, phase 3, non-inferiority trial In patients with resectable oesophageal squamous cell carcinoma, robot-assisted oesophagectomy was non-inferior, and seemed superior, to thoracoscopic oesophagectomy in terms of 5-year overall surviva...

🆕 Robot-assisted versus conventional minimally invasive oesophagectomy for oesophageal squamous cell carcinoma (RAMIE): a multicentre, open-label, randomised, phase 3, non-inferiority trial

www.thelancet.com/journals/lan...

#GastroSky #OncSky #SurgSky

Histopathological predictor of response to mirikizumab in active ulcerative colitis Successful use of mirikizumab in three patients with active ulcerative colitis was guided by clinical presentation plus high neutrophilic infiltration of the colonic epithelium (Geboes Grade 3.2).

#MedCase - Successful use of #mirikizumab in three patients with active #UlcerativeColitis was guided by clinical presentation plus high neutrophilic infiltration of the colonic epithelium (Geboes Grade 3.2).

👉 buff.ly/X3BPJaA

#GISky #GastroSky

Images in Clinical Medicine Walled-Off Pancreatic Necrosis Panels A and B: Computed tomography of the abdomen

A woman with a history of necrotizing pancreatitis presented with abdominal pain and fevers. CT showed a fluid collection with gas and septations in the pancreatic region. A retroperitoneal necrosectomy was performed (shown in a video). Read the full case details: nej.md/4rXQvBB

#MedSky #GastroSky

3D human liver reconstruction reveals changes in cirrhosis A new 3D reconstruction of human liver tissue revealed changes to the liver’s internal structure in liver disease.

To better understand how cirrhosis reshapes the liver and impacts its function, a UW team led by @kellystevens.bsky.social developed the LiverMap pipeline and used it to generate a high-resolution 3D reconstruction of the human liver.

www.nih.gov/news-events/...

#hepatology #gastrosky 🧪

Beyond the Flare: A Case of Disseminated Tuberculosis and Thrombosis Masquerading as IBD Exacerbation A woman taking adalimumab for ileocolic Crohn’s disease presented with symptoms mimicking a flare. CT revealed extensive venous thrombosis, but respiratory symptoms developed and disseminated…

#MedCase - A woman taking #adalimumab for ileocolic #CrohnsDisease presented with symptoms mimicking a flare.

CT revealed extensive venous thrombosis, but respiratory symptoms developed and disseminated TB was diagnosed.

👉 buff.ly/eRNp0P9

#GastroSky #IDSky

The effect of alcohol minimum unit pricing and cancer warning labels on cancer incidence and mortality in Canada: an epidemiological modelling study Alcohol policies, particularly those combining pricing and labelling, could substantially reduce the cancer burden and health inequalities.

New The Lancet Public Health - The effect of alcohol minimum unit pricing and cancer warning labels on cancer incidence and mortality in Canada: an epidemiological modelling study

www.thelancet.com/journals/lan...

#GastroSky #MedSky #LiverSky

🆕Indocyanine green fluorescence angiography for anastomotic perfusion assessment in colorectal surgery: a systematic review with meta-analysis, meta-regression, and trial sequential analyses

www.thelancet.com/journals/lan...

#GastroSky #SurgSky #MedSky

#Hypertriglyceridaemia-induced acute #pancreatitis is a complex inflammatory disease that requires immediate medical attention and supportive care www.thelancet.com/journals/lan...
#triglycerides

#MedSky #EndoSky #GastroSky

A map showing age-standardized incidence rates of gastric cancer among men and women in 2022 according to country.

The IARC Working Group summarizes guidance on 𝘏. 𝘱𝘺𝘭𝘰𝘳𝘪 screen-and-treat programs for gastric cancer prevention and concludes that prevention is the most effective strategy amid a rising global burden. Learn more: nej.md/47xUm0E

#MedSky #Oncology #GastroSky

Ulcerative colitis, pathophysiological mechanisms and drug repurposing: a new therapeutic dawn-narrative review A significant proportion of people with ulcerative colitis don’t respond to the currently available treatments or lose response over time. Could repurposed medications offer a new way forward and how…

A significant proportion of people with #UlcerativeColitis don’t respond to the currently available treatments or lose response over time.

Could repurposed medications offer a new way forward and how might they be used?

👉 buff.ly/gbtsVKo

#GastroSky #IBD

Figure 1. Correctly Identified Safe and Unsafe NGT by AI in our Study (True-Positive and True-Negative Cases).

Figure 2. Examples of False-Negative Cases.

Figure 3. Examples of False-Positive Cases — CXRs Showing “Safe” NGTs Identified Incorrectly as “Suboptimal” (Unsafe) by the AI Tool.

Original Article by A.-M. Bartsch et al.: External Validation of a Commercially Available AI Tool for Nasogastric Tube Position Decision Support in the NHS: A Prospective Silent Trial nejm.ai/46nhZbS

#AI #MedSky #GastroSky

The April 2026 issue of @lancetgastrohep.bsky.social is out today at www.thelancet.com/gastrohep

This month's issue features content on #IBD, #cirrhosis, #pancreaticcancer, #viralhepatitis, #MASLD + more...

#GastroSky #MedSky #LiverSky

Why the National Zoo is feeding its baby elephant poop In a novel move, feces from a baby elephant in Ohio were shipped to the zoo and mixed with Linh Mai’s formula.

The new baby elephant at DC's zoo is receiving fecal transplants--by mouth--to stave off diarrhea.

#Gastrosky #microbiome #guthealth #Smithsonian #veterinarymedicine #medicine #Medsky

Deciphering whipple’s disease complexity The latest insights into Whipple disease, from epidemiology and pathophysiology to clinical manifestations and treatment. Explore confounding factors in diagnosis and management, and current…

Get the latest insights into #WhippleDisease, from epidemiology and pathophysiology to clinical manifestations and treatment, in this review.

Explore confounding factors in diagnosis and management, and current treatment limitations.

👉 buff.ly/FkYiR7r

#IDSky #GastroSky

Figure 1. Correctly Identified Safe and Unsafe NGT by AI in our Study (True-Positive and True-Negative Cases).

In a new study, a commercially available #AI tool for detecting nasogastric tube placement on chest radiographs demonstrated high sensitivity and negative predictive value, but its false-negative rate raised patient safety concerns. Full study results: nejm.ai/46nhZbS

#MedSky #GastroSky

Early ileocecal resection offers long-term remission for some Crohn’s disease patients Ten-year results of the LIR!C trial suggest that ileocecal resection offers a higher rate of long-term, therapy-free remission than infliximab for patients with uncomplicated ileocecal Crohn’s disease.

#MedNews - Ten-year results of the LIR!C trial suggest that ileocecal resection offers a higher rate of long-term, therapy-free remission than #infliximab for patients with uncomplicated ileocecal #CrohnsDisease.

Full story 👉 buff.ly/tWuNGOQ

#GastroSky

"ACG Clinical Guideline: Hepatic Encephalopathy."
Publié en mars dans Am J Gastroenterol.
#MedSky #LiverSky #GastroSky
journals.lww.com/ajg/fulltext...

ETVAX protects against infant enterotoxigenic E. coli diarrhea An oral whole-cell vaccine against enterotoxigenic Escherichia coli is immunogenic and well tolerated in infants, and should advance to a phase 3 trial.

#MedNews - An oral whole-cell vaccine against enterotoxigenic #EColi is immunogenic and well tolerated in infants, and should advance to a phase 3 trial.

👉 buff.ly/72hPj2b

#IDMed #GastroSky

The #cow gags it up for a
chew,
To grind every morsel to goo.
The #rabbit, instead,
Finds #nutrients spread,
In droppings it eats as if new.

#vss365 #limerick #animals #poetry
#coprophagy & #ruminant #regurgitation
#digestion #nutrition #copremesis
#biosky #biochemistry #gastrology #gastrosky
🔬 🧪 ⚗️

Please join us on 4/23 for our Research Day on "Advancing #HealthEquity"!

#MedSky #GISky #Gastrosky

Sorry, you did WHAT with the vibrating diabetic mouse? | Medical News Bulletin In a study, published in the International Journal of Molecular Sciences, researchers set out to investigate the mechanism by which it influences inflammation. The study utilized two sets of male mice...

Could whole body vibration be the hack type 2 diabetics need to keep their blood glucose levels under control? Have a read of the evidence and you tell me. medicalnewsbulletin.com/whole-body-v... 🧪 #GastroSky medsky, 🩺,⚕️ microbiome 🦠

Phase 2 data support further development of efimosfermin for MASH-related fibrosis The FGF21 analog efimosfermin alfa significantly improves fibrosis regression and is well tolerated in people with MASH and moderate or advanced fibrosis.

#MedNews - The FGF21 analog efimosfermin alfa significantly improves fibrosis regression and is well tolerated in people with #MASH and moderate or advanced fibrosis.

Full story 👉 buff.ly/zxlbNW7

#GastroSky #HepSky

Translating IBD Genomics into Clinical Practice Advances in genomics are steadily reshaping the clinical management of IBD. As genomic technologies become more accessible, incorporation into routine IBD care has the potential to move towards…

Advances in genomics are steadily reshaping the clinical management of #IBD.

As genomic technologies become more accessible, incorporation into routine IBD care has the potential to move towards personalized medicine.

👉 buff.ly/1CocNiQ

#GastroSky

Esophageal bezoar formation following enteral nutrition Dysphagia and nasogastric tube obstruction occurred after 5 days of enteral feeding following cardiothoracic surgery. Upper endoscopy revealed a large, whitish bezoar completely filling the…

#MedCase - Dysphagia and nasogastric tube obstruction occurred after 5 days of enteral feeding following cardiothoracic surgery. Upper endoscopy revealed a large, whitish bezoar completely filling the esophageal lumen.

👉 buff.ly/lzhr7wW

#GastroSky