#MedCase - A woman with a history of hepatic #echinococcosis presented with pulmonary lesions that did not improve with antiparasitic therapy, prompting rheumatologic evaluation and a diagnosis of granulomatosis with polyangiitis.
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#RheumSky
#MedCase - IRVAN risks severe vision loss in refractory cases.
In this case, marked improvement after anti-VEGF failure suggests #adalimumab may be an effective option that targets underlying inflammation.
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#EyeSky
#MedCase - A case of fulminant #T1D in a woman on #tislelizumab for lung adenocarcinoma highlights the need for proactive monitoring of fasting glucose, HbA1c, and islet function in people given an ICI.
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#Diabetes #OncSky
#MedCase - A woman taking #adalimumab for ileocolic #CrohnsDisease presented with symptoms mimicking a flare.
CT revealed extensive venous thrombosis, but respiratory symptoms developed and disseminated TB was diagnosed.
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#GastroSky #IDSky
#MedCase - The first report of late-onset axial #spondyloarthritis presenting with fever of unknown origin.
Physicians need to be aware of rare manifestations of ax-SpA in the elderly population.
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#RheumSky #MedSky
#MedCase - Consider testing thyroid function in patients receiving #pomalidomide prior to and then every 2–3 months during treatment. If drug-induced #hypothyroidism occurs, once the patient reaches a state of euthyroidism, rechallenge can be feasible.
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#OncSky
This landmark #MedCase documents the first human whole eye allotransplant following high-voltage electrical injury.
Sustained globe viability & preserved outer retinal function at 1 year support its feasibility, despite absent visual perception.
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#EyeSky #MedSky
#MedCase - A reminder to consider #methotrexate as a potential cause of #gynecomastia, even with long-term low-dose therapy and in euhormonal states.
Conservative measures such as dose reduction or folate supplementation may lead to symptom reversal.
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#RheumSky
#MedCase - Management of Lutembacher’s syndrome during pregnancy requires a coordinated, multidisciplinary approach to mitigate high risk complications.
This case highlights the challenges of its management in a low-resource setting.
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#CardioSky
#MedCase - #KrabbeDisease usually occurs in infancy, but adult-onset cases are increasingly described.
KD should always be considered in very late-onset spastic paraplegia, as in this 66-year-old with concomitant cognitive decline.
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#NeuroSky
#MedCase - This case of a #TesticularCancer patient with #CysticFibrosis and #LiverCirrhosis shows that monitoring of #etoposide concentrations can be beneficial in complex scenarios involving organ dysfunction and/or potential drug–drug interactions.
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#OncSky
#MedCase - Slight pain related to eye movement and decreased VA indicated #papillitis.
Rapid vision loss revealed an unusual initial finding of optic nerve involvement preceding retinal necrosis.
But what was the cause?
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#EyeSky #IDSky
#MedCase - A unique case of both #MOGAD and emergent #lupus developing after anti-TNF treatment in a patient with ankylosing #spondylitis, highlighting the need for increased clinical awareness of the immunological consequences of TNF blockade.
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#RheumSky
#MedCase - FDG-PET/CT is invaluable in identifying synchronous infective foci, as this case of concurrent infective native aortic aneurysm and T9-T10 spondylodiscitis in an elderly patient with recurring S. enterica bacteremia, highlights.
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#IDSky #CardioSky #RheumSky
#MedCase - Dysphagia and nasogastric tube obstruction occurred after 5 days of enteral feeding following cardiothoracic surgery. Upper endoscopy revealed a large, whitish bezoar completely filling the esophageal lumen.
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#GastroSky
#MedCase - A case of immune-related #gastritis complicated by subsequent CMV #gastritis in a patient undergoing combination therapy with #ipilimumab and #nivolumab for renal cell carcinoma.
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#OncSky
#MedCase - An unusual case of Vogt-Koyanagi-Harada syndrome emerging after a trip above 2500 m, presenting with low visual acuity, conjunctival injection, and retinal detachment.
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#EyeMed #EyeSky
#MedCase - A continuous infusion of ATM-AVI following a full-vial loading dose was successful in treating a complex, deep-seated K. pneumoniae infection, possibly providing a rational, stewardship-conscious dosing approach for severe MBL infections.
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#IDSky #NeuroSky
#MedCase - This case of subacute inferolateral #MI secondary to coronary thrombosis occurring after adjuvant doxorubicin–cyclophosphamide therapy in a patient with #BreastCancer underscores the need for vigilance for uncommon, yet life-threatening, complications.
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#OncSky
#MedCase - Purtscher #retinopathy is usually related to trauma. But, in this rare case, cotton wool spots with few hemorrhages revealed left-eye Purtscher‑like retinopathy developing after endogenous panophthalmitis in the right eye.
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#EyeSky
#MedCase - #Tularemia is typically linked to ticks, hares and contaminated water or dust.
In an unusual case from Southern Germany, this patient developed headache, chills, fatigue and swollen lymph nodes following a squirrel bite.
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#IDSky
#MedCase - Coronary aneurysms may present with nonspecific symptoms, delaying appropriate management.
A suspected cardiac tumor in this patient was revealed to be a giant RCA aneurysm, which was successfully managed with surgery.
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#CardioSky
#MedCase - A case of eosinophilic #cholangitis presenting as a localized biliary stricture in a 65-year-old man.
As perihilar cholangiocarcinoma could not be ruled out, the patient opted for surgical intervention.
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#GastroSky
#MedCase - An 81-year-old receiving #upadacitinib for RA developed CMV #retinitis complicated by delayed retinal ischemia and vitreous hemorrhage.
Clinicians should be vigilant for atypical ocular complications from JAK inhibitors.
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#EyeSky #IDSky #arthritis
#MedCase - Familial thyroid cancers are well documented, but in this rare report one monozygotic twin sister had metastatic poorly differentiated thyroid carcinoma and the other recurrent papillary thyroid carcinoma.
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#OncSky #ThyroidCancer
#MedCase - A 37-year-old woman developed acute #encephalopathy and treatment-induced #neuropathy of diabetes after 3 months of #semaglutide use.
Benefits of #GLP1 agonists outweigh the risks, but clinicians should be alert to potential sequelae.
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#NeuroSky
#MedCase - Echocardiography revealed a 3 mm Type I APW with minor hypertension in a 3-year-old girl. Transcatheter coil occlusion was successful in closing the defect, highlighting its role as an alternative to surgical repair.
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#CardioSky #CongenitalHeartDisease
#MedCase - An extremely rare case of #dermatomyositis concomitant with IgA nephropathy.
Although the possibility of coincidental co-occurrence cannot be ruled out, it seems more likely that a common pathologic mechanism plays a role.
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#IgANephropathy #RheumSky
#MedCase - STA is a safer alternative to needle-based techniques, but this case of acute vision loss, ptosis, ophthalmoplegia, and mydriasis after #ropivacaine injection during cataract + macular surgery highlights the potential for rare but reversible complications.
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#EyeSky
#MedCase - Recognize the importance of considering Kawasaki disease in infants presenting with prolonged, antibiotic-resistant fever, even though the condition is uncommon in children younger than 6-months.
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#CardioSky #PediatricCardiology
