Methotrexate-associated gynecomastia A reminder to consider methotrexate as a potential cause of gynecomastia, even with long-term low-dose therapy and in euhormonal states. Conservative measures such as dose reduction or folate…

#MedCase - A reminder to consider #methotrexate as a potential cause of #gynecomastia, even with long-term low-dose therapy and in euhormonal states.

Conservative measures such as dose reduction or folate supplementation may lead to symptom reversal.

👉 buff.ly/vzpk94B

#RheumSky

Coroner flags lack of clarity around expanded role of community pharmacists under Pharmacy First A coroner has raised concerns about outdated methotrexate guidance and a lack of clarity around the role of community pharmacists under the Pharmacy First scheme, following the death of a patient. In…

A coroner has raised concerns about outdated #methotrexate guidance and a lack of clarity around the role of community pharmacists under the #PharmacyFirst scheme, following the death of a patient

buff.ly/1ILE0id

Methotrexate osteopathy in rheumatoid arthritis A case series describing four women with rheumatoid arthritis who presented with stress fractures and showed rapid clinical improvement after discontinuation of methotrexate.

#MedCase - Four women with rheumatoid #arthritis presented with stress fractures showed rapid clinical improvement after discontinuation of #methotrexate.

👉 buff.ly/vfekID7

#RheumSky

My art piece, a person missing a hand, drawn from the upper abdomen to the head. The head is a little large like a child's and the body thin and slightly bloated as if they are malnourished. The colors are yellow orange and brown to mix and be reminiscent to the medication that inspired the piece, methotrexate.

Me standing infront of my art piece

Me standing infront of the gate at the School of Arts and Culture (Mexican Heritage Plaza) in San Jose

Flowers and candy for the big day, one of the best days of my life

My piece, Methotrexate, in a gallery in SanJose. I got to spend it with someone special, it was the best day of my life.
#art #artwork #drawing #painting #mixedmedia #oilpaint #acrylic #oilpastel #recycledpaper #methotrexate #foxhoundp99 #mexicanheritagemuseum #schoolofart&culture

GPhC writes to pharmacy teams after methotrexate dispensed with instruction to take once daily The pharmacy regulator has written to pharmacy teams after it received a concern that methotrexate had been dispensed with a label instructing a patient to take the medication once daily rather than…

The #GPhC has written to pharmacy teams after following reports that #methotrexate had been dispensed with instructions to take it once daily rather than once weekly

#medicationsafety #pharmacyregulator #ukhealthcare

buff.ly/RBgDgAl

Methotrexate Intolerance Affects a Significant Percentage of Patients With RA Results of a cross-sectional study in India showed that a significant percentage of adults with RA are intolerant to MTX.

#Methotrexate intolerance was observed among 34.5% of the study cohort with rheumatoid arthritis. #RA

Read More: https://bit.ly/4p6tpHB

This study shows that a TPM regimen of #thalidomide, #prednisone, and #methotrexate is a highly effective and safe treatment for symptomatic #LGLL, achieving a 75% complete remission rate and durable responses with manageable adverse effects.

#STTT: doi.org/10.1038/s413...

#Arthritis30
#Osteoarthritis #RheumatoidArthritis #Spondyloarthritis #SeronegativeArthritis #JointPain #AutoimmuneDisease #Inflammation #Orthopedics #Rheumatology #HeberdenNodes #BouchardNodes #SwanNeckDeformity #BoutonniereDeformity #HLA_B27 #DMARDs #NSAIDs #Methotrexate #JointHealth

Having a family dr who listens is my saving grace while dealing with crippling PsA. My rheum dr is good too. I have heard nightmare stories, so even though we are still trialing to find a med that works - at least i’m acknowledged
#chronicpain #psoriaticarthritis #rinvoq #talz #methotrexate

The Doctor Said… I started crying today. Because of stupid facebook and a bunch of other stuff. But I’m telling you, every single time that I try to reach out or comment on someone’s post on facebook, it backfires …

#adelusionalpredisposition

#mentalillness #disability #rheumatoidarthritis #arthritis #bonespurs #hurdles #chronicpain #pain #jointstiffness #kneereplacements #bonefusions #bigtoe #ankles #knees #methotrexate #medications #painmanagement #schizoaffectivedisorder #episodes #stigma

Cyclosporin-Cyclophosphamide Performs Well for GVHD Prevention After Transplant | ASH Clinical News | American Society of Hematology

Patients who received #cyclosporin and #cyclophosphamide for #GVHD prevention after #HCT had improved outcomes compared to those receiving the standard cyclosporin and #methotrexate, with a median GRFS of 26.2 months vs. 6.4 months: ow.ly/pOA250WXckE #HemeSky #HemeOnc

Eyes on fire: a diagnostic and therapeutic dilemma Methotrexate resolved severe bilateral scleritis after adalimumab failed. Could conventional disease-modifying antirheumatic drugs outperform biologics in select ocular autoimmune cases with complex inflammatory...

#MedCase - Methotrexate resolved severe bilateral #scleritis after #adalimumab failed.

Could conventional disease-modifying antirheumatic drugs outperform biologics in select ocular autoimmune cases with complex inflammatory pathways?

👉 buff.ly/ryIfCox

#EyeMed #Methotrexate

It’s #methotrexate day for my #RA, and my stomach has been big mad. Made the mistake of taking Pepto Bismol pills, so having to wait to actually take the methotrexate.

But my edible finally peaked and I’m trying to convince my brain that we do not need carne asada fries to toss into this mess 🥺.

Uncertainty over need for early biologic DMARD addition to methotrexate in psoriatic arthritis In untreated patients with a recent psoriatic arthritis diagnosis, methotrexate alone or combined with golimumab significantly reduces disease activity.

#MedNews - In untreated patients with a recent #PsoriaticArthritis diagnosis, #methotrexate alone or combined with #golimumab significantly reduces disease activity.

Full story 👉 buff.ly/H7q2qK0

#RheumTwitter #DMARDs

#pharmacology19
#Immunosuppressants #AutoimmuneDisease #RheumatoidArthritis #Lupus #Psoriasis #TransplantCare #Methotrexate #Hydroxychloroquine #Cyclosporine #TNFInhibitors #Pharmacology #NursingStudents #MedicalEducation #MedSchool #HealthcareTips #PatientSafety #DrugSafety

Arthritis Drug, Methotrexate, Might Have Additional Heart-Healthy Benefit - Drugs.com MedNews TUESDAY, Sept. 9, 2025 A common rheumatoid arthritis drug appears to also lower blood pressure, potentially reducing patients risk of heart disease, a new study

New study: #Methotrexate, a common rheumatoid arthritis drug, lowers blood pressure by 7.4 mm/Hg compared to sulfasalazine. This could reduce heart attack and stroke risk for RA patients. Published in Annals of Medicine. www.drugs.com/news/arthrit...

Anyone else have good results with #Kesimpta for MS? I'm starting it tomorrow, and rather nervous. 😓 I've been on #Rituximab awhile, and it worked well, but I've developed an allergic reaction, so have to switch. Also had to stop #Methotrexate for PsA, due to it not working, plus bad side effects. 🥲

Management of primary central nervous system lymphoma and coexisting heart failure with reduced ejection fraction: a narrative review Explore current treatments for primary central nervous system lymphoma, including those involving high-dose methotrexate, and their implications for patients with heart failure with reduced ejection…

Explore current treatments for primary central nervous system lymphoma, including those involving high-dose #methotrexate, and their implications for patients with #HFrEF.

👉https://buff.ly/hHicXoQ

#NeuroSky #PCNSL

Delaying methotrexate improves pneumococcal vaccine response in early RA Postponing methotrexate treatment by 1 month after pneumococcal vaccination significantly enhances the immune response in patients with rheumatoid arthritis.

#MedNews - Postponing #methotrexate treatment by 1 month after pneumococcal vaccination significantly enhances the immune response in patients with #RheumatoidArthritis.

👉 buff.ly/xKLWOxt

#RheumSky

🎙️ New #jointaction podcast on all things #methotrexate

Joint David Hunter with guests Robin Christensen, BSc, MSc, PhD Anna Døssing to learn more 👇

Podcast link: www.jointaction.info/podcast/epis...

Editorial link: pubmed.ncbi.nlm.nih.gov/40222629/

Researchers at #HKUMed combined the active ingredient extracted from the #TraditionalChineseMedicine #TCM Astragalus membranaceus (#huangqi) with #methotrexate #MTX to reduce chronic #inflammation in #autoimmunediseases.
✅ academic.oup.com/jleukbio/art...
✅ www.nature.com/articles/s41...

We’ve been working together with the University of Manchester Biomedical Research Centre to publish this article looking at stratified medicine. The article discusses how #methotrexate is still given as a first line treatment for #JIA for most children and young people despite the side-effects.

Methotrexate Intolerance Not Tied to Administration Route Methotrexate intolerance in RA patients was not linked to dosing frequency or administration route, suggesting other factors like age may play a more significant role.

💊 New study finds methotrexate intolerance in RA isn’t significantly affected by dosing route or frequency.
Full article ➡️ www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #Methotrexate #RA #PatientCare #ClinicalResearch

Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors MTX exerts antitumor immune activity by inducing cGAMP generation in cancer cells and concurrently inhibiting its hydrolysis mediated by ENPP1.

#medsky🧪 #oncosky #pharmasky The approved Rx #methotrexate can potentiate #antitumor immune activity & boosting the efficacy of checkpoint blockade #immunotherapy in patients with solid tumors to a preliminary #clinicaltrial.

www.science.org/doi/10.1126/...

www.science.org/doi/10.1126/...

Identification and validation of interferon-driven gene signature as a predictor of response to methotrexate in juvenile idiopathic arthritis To identify and validate gene expression biomarkers of response to methotrexate (MTX) treatment in peripheral blood of children with juvenile idiopathic arthritis (JIA) measured before starting MTX tr...

So excited to see this out! ard.eular.org/article/S000... #JIA and #methotrexate response for the CLUSTER consortium 🤠

#Methotrexate day was yesterday, and I am feeling incredibly ill today.

It’s a rough immunesuppressant, and it usually fucks up my stomach, but I think it’s *extra* mad because I’m taking antibiotics currently.

Even my Zofran didn’t help this time. Here’s hoping the edible kicks in soon.

#sick

a woman in a blue dress is standing in front of a bed with an alarm clock on the nightstand that says 4:20 Alt: a woman in a blue dress is standing in front of a bed with an alarm clock on the nightstand that says 4:20

Me, the day after I take my weekly dose of #methotrexate:

#PsoriaticArthritis #PsA #BloodyExhausting

New article to read! Common genetic variants do not impact clinical prediction of #methotrexate treatment outcomes in early #rheumatoid arthritis.

➡️ Predicting MTX treatment outcomes remains a challenge

🔗 doi.org/10.1111/joim.20087

a man is walking down a hallway with a suitcase and a backpack . ALT: a man is walking down a hallway with a suitcase and a backpack .

Damn you, chronic fatigue...
#PsoriaticArthritis #Methotrexate #PsA