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Home-Based Video Exercise Program After Lumbar Surgery A home-based video-guided exercise programme improved long-term disability, function, and fear of movement after lumbar spine surgery, with early reductions in depressive symptoms versus standard care...

🎥🧠 Home video-guided exercise after lumbar surgery was linked to lower disability and less fear of movement over 24 months. QoL improved too.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Rehab

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Volumetric Bone Loss Seen in Knee Osteoarthritis Radiographic knee osteoarthritis was associated with slightly higher DXA aBMD but lower tibial cortical volumetric bone mineral density, highlighting a potential mismatch between density measures and ...

🦴🦵 Knee OA linked to lower tibial cortical vBMD, even as DXA BMD looked slightly higher.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Osteoarthritis

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Why Some Knee Osteoarthritis Pain Runs Hotter In an IMI APPROACH cohort, an inflammation biomarker subtype aligned with worse knee osteoarthritis pain outcomes across questionnaires, while MRI damage patterns mainly tracked nociceptive like pain ...

🧬🦵 Some knee OA pain runs hotter.

www.emjreviews.com/en-us/amj/rh...

Inflammation biomarker subtype tied to KOOS/WOMAC pain and PainDETECT; MRI damage showed weaker links.

#AMJRheumatology #KneeOA

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How Does Bone Manipulation Influence Wound Healing? This case series reports limb salvage with transverse tibial transport showing complete healing in recalcitrant diabetic foot ulcers with no pin site infections.

🦴✨ Bone manipulation may enhance wound healing by boosting microcirculation and tissue repair. Study links effect to angiogenesis.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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Weight Gain Rates Stabilize After TNF Inhibitor Initiation Tumor necrosis factor inhibitors were not linked to additional weight gain in patients with psoriatic arthritis when age-related changes were considered.

🧬 New study finds TNF inhibitors do not accelerate weight gain in psoriatic arthritis. In fact, the pace of weight increase slowed after treatment, offering reassurance for long-term metabolic management.

www.emjreviews.com/rheumatology...

#AMJRheumatology #AutoimmuneDisease #PsoriaticArthritis

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Psoriatic Arthritis Shows Lower Cardiorespiratory Fitness Levels Cross-sectional testing shows reduced cardiorespiratory fitness in psoriatic arthritis, with disease activity and adiposity linked to lower VO2peak and self-reported activity linked to higher fitness.

💪 New research reveals that people with psoriatic arthritis have markedly reduced cardiorespiratory fitness versus healthy controls, underscoring the need for early lifestyle interventions to improve long-term health outcomes.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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Advanced Drug Delivery Improves Gout Management Emerging drug delivery systems improve solubility, targeting, and sustained release, offering promise for enhanced gout and hyperuricemia management.

🧪💊 Advanced drug delivery may improve gout care. Targeted lipid/polymer systems enable sustained release and tolerability to support adherence.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Gout

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Children Weaned Off Steroids Avoid Crises Retrospective study finds adrenal crisis is rare after weaning high dose glucocorticoids in children with nephrotic syndrome or juvenile idiopathic arthritis, supporting protocolized tapering under sp...

⚠️ New evidence shows children with rheumatologic disease who are carefully weaned off long-term steroids face fewer adrenal crises, underscoring the importance of monitored tapering in clinical practice.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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New Criteria Improve Lupus Detection in Autoimmune Lung Disease A new study finds that EULAR/ACR criteria identify more systemic lupus erythematosus cases among patients with interstitial pneumonia with autoimmune features than older methods.

🧬 Updated lupus criteria improve diagnosis in autoimmune lung disease. Researchers found EULAR/ACR standards identified SLE more effectively than SLICC in patients with interstitial pneumonia with autoimmune features.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease #Lupus

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Study Connects Gut Microbes to Lung Scarring International research reveals that specific gut bacteria are linked to the presence and severity of interstitial lung disease in systemic sclerosis, highlighting potential therapeutic targets within ...

🧬 Gut microbes may hold the key to lung scarring in systemic sclerosis. An international study found distinct bacterial species linked to ILD severity, offering fresh insight into autoimmune mechanisms.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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New Algorithm Forecasts NSAID Efficacy for Knee Pain Machine learning predicts pain relief in knee osteoarthritis with 85% accuracy by integrating pain sensitization, inflammation, microRNA, and psychological factors, advancing personalized management o...

🧠 Machine learning shows promise in tailoring knee osteoarthritis treatment. A new algorithm forecasts NSAID + paracetamol response with 85% accuracy, moving closer to personalized pain care.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Osteoarthritis #PainManagement

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Canakinumab Outperforms Anakinra in VEXAS Syndrome Canakinumab showed superior efficacy, longer drug survival, and fewer adverse events than anakinra in patients with VEXAS syndrome, supporting its role as an effective steroid-sparing option.

💉 Canakinumab significantly outperforms anakinra in VEXAS syndrome, demonstrating stronger efficacy, longer drug survival, and fewer adverse events, making it a promising steroid-sparing treatment for patients.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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Surgeons Confront Complex Realities in Knee Pain Care Surgeons managing unexplained pain after knee arthroplasty face clinical, emotional, and ethical challenges. New findings highlight the need for holistic patient-centered care and collaborative manage...

🦵 Surgeons managing unexplained pain after knee arthroplasty report difficult consultations, reluctance over revision surgery, and lasting emotional weight, underscoring the call for patient-centred, collaborative care.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Orthopedics #PatientCare

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Demand for Rheumatology Advice Lines Outpaces Resources Survey of 1,423 patients reveals rheumatology advice lines are valued but limited by delays and automation. Patients want faster responses, more availability, and direct staff support.

📞 Patients are calling for quicker, more personal rheumatology advice line support. With most seeking help for flares, pain, and medications, rising demand shows the need to redesign services for timely access.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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Treatment Patterns in Mantle Cell Lymphoma: Insights from Japan Real-world study in Japan highlights treatment patterns, outcomes, and physician goals for mantle cell lymphoma, revealing unmet needs in efficacy, safety, and quality of life.

🧪 Insights from Japan reveal real-world mantle cell lymphoma care: first-line chemotherapy often delivers complete responses, while BTK inhibitors provide partial responses with fewer adverse events, improving daily life impact.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Lymphoma

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Effectiveness of IL-6 Therapy in the Elderly with Rheumatoid Arthritis IL-6 inhibitors show favorable safety and effectiveness in older rheumatoid arthritis patients, supporting their growing role in managing RA and other immune-mediated diseases in aging populations.

🧬 IL-6 blockade remains safe and effective in elderly patients with RA. Sarilumab shows consistent results across age groups, while tocilizumab effectiveness is slightly lower in older adults.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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Effectiveness of IL-6 Therapy in the Elderly with Rheumatoid Arthritis IL-6 inhibitors show favorable safety and effectiveness in older rheumatoid arthritis patients, supporting their growing role in managing RA and other immune-mediated diseases in aging populations.

🧬 IL-6 blockade remains safe and effective in elderly patients with RA. Sarilumab shows consistent results across age groups, while tocilizumab effectiveness is slightly lower in older adults.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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Salivary Ultrasound Adds Value in Sjögren’s Diagnosis Salivary gland ultrasound showed diagnostic value in suspected Sjögren’s Disease, especially when combined with biopsy or antibody testing, highlighting its potential role in future classification cri...

🔍 Salivary ultrasound strengthens Sjögren’s diagnosis. Higher SGUS grades, particularly Grade 3, closely track with biopsy positivity and reduced saliva flow, making SGUS a valuable non-invasive diagnostic tool for clinicians.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease

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ILD Progression in Rheumatoid Arthritis Linked to Mortality Rheumatoid arthritis associated interstitial lung disease shows high progression and mortality rates, with UIP pattern strongly linked to outcomes, emphasizing the need for vigilant, personalized mana...

🫁 In adults with rheumatoid arthritis-associated ILD, disease progression and UIP pattern significantly raise mortality, methotrexate had no effect on survival.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Pulmonology #RAILD

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Can Power Doppler Forecast Remission in Rheumatoid Arthritis? Power Doppler ultrasound may help predict rheumatoid arthritis treatment response, though its role in forecasting remission remains uncertain, according to a systematic review of clinical studies.

🩺 Power Doppler ultrasound may help predict rheumatoid arthritis treatment response, though its role in forecasting remission is still uncertain. New systematic review findings.

www.emjreviews.com/en-us/amj/rh...

#Rheumatology #RheumatoidArthritis #AMJRheumatology

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🫀 Real-world data show IL-1 inhibitors are replacing steroids in recurrent pericarditis. The move toward steroid-sparing care is changing treatment decisions.

Read more here: www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Pericarditis #Inflammation #IL1Inhibition

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Ultrasound Pinpoints Key Psoriatic Arthritis Phenotypes Ultrasound-based phenotyping distinguishes inflammatory and non-inflammatory forms of difficult-to-treat psoriatic arthritis, supporting more tailored treatment strategies for refractory patients.

🩻 Ultrasound distinguishes inflammatory and non-inflammatory psoriatic arthritis, helping guide targeted therapy for difficult-to-treat patients.

www.emjreviews.com/en-us/amj/rh...

#PsoriaticArthritis #Rheumatology #AMJRheumatology

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New AI Models Advance Knee Osteoarthritis Prediction Recent machine learning advances are improving prediction of clinical, imaging, and surgical outcomes in knee osteoarthritis, enabling earlier detection, risk stratification, and personalized interven...

🦵 New AI tools are advancing how clinicians predict knee osteoarthritis outcomes, from subtle MRI changes to surgical risk, enabling earlier detection, refined risk profiles, and personalised interventions.

www.emjreviews.com/en-us/amj/rh...

#Osteoarthritis #AI #MachineLearning #AMJRheumatology

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IL-1 Inhibitors Effective for Refractory SURF Cases Study identifies aphthous stomatitis as a predictor of colchicine resistance in SURF and supports IL-1 inhibitors for refractory cases, highlighting the need for personalised management.

🔥🩺 Aphthous stomatitis may predict colchicine resistance in patients with SURF. IL-1 inhibitors like anakinra & canakinumab could benefit refractory cases.

🔗 www.emjreviews.com/en-us/amj/il...

#SURF #ColchicineResistance #IL1Inhibitors #Rheumatology #AMJRheumatology

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Interruptions Undermine Lupus Decision Aid Impact Viewing lupus decision aids without interruption leads to better patient-reported outcomes, regardless of whether they are delivered at home or in the clinic via any device.

New study shows it’s not where or how lupus decision aids are viewed, but whether they’re seen fully and without interruption that drives better outcomes.

Read more @amjreviews.bsky.social: www.emjreviews.com/en-us/amj/rh...

#Lupus #AMJRheumatology #PatientCare

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Routine Biopsy May Be Key to Catching Lupus Nephritis Early Recurrent lupus nephritis post-transplant may go undetected without surveillance biopsies. This study reveals high recurrence rates and early histologic changes, especially in African American patient...

🧪 Routine surveillance biopsies post-kidney transplant uncover silent 🦠 lupus nephritis in 1 in 3 patients, often early & without symptoms. Most show mesangioproliferative injury. Early biopsy = early action.

#LupusNephritis #TransplantCare #AMJRheumatology

🔗 www.emjreviews.com/en-us/amj/rh...

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Rheumatoid Arthritis Therapy Hinges on Infection Check Thorough screening for latent TB, hepatitis B, and hepatitis C before b/tsDMARD therapy in RA patients improves safety and outcomes, especially in high-burden regions, audit shows.

🦠 Patients with RA on biologics need infection screening first!
Audit finds missed tests for TB, Hep B & C before starting DMARDs.
Missed checks = patient risk.
📖 www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #PatientSafety #DMARDs

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Stem Cell Strategies Show Promise in Systemic Sclerosis Stem cell therapies offer emerging hope for systemic sclerosis, with autologous and mesenchymal options under investigation for their immunosuppressive and antifibrotic potential.

🌱 New hope for systemic sclerosis: Stem cell strategies show promise in reversing skin and lung symptoms. Researchers urge further investigation. Full story by #AMJRheumatology 📰: www.emjreviews.com/en-us/amj/rh...

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Common Osteoarthritis Genes Not Linked to Progression Genetic markers for knee osteoarthritis presence do not predict disease progression, but 19 new variants tied to joint space loss suggest novel progression pathways.

🧬 Risk genes for knee osteoarthritis aren’t linked to disease worsening, study shows. But 19 new variants may help predict progression via joint space narrowing. A step forward in biomarker discovery.

Read more: www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology

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Methotrexate Intolerance Not Tied to Administration Route Methotrexate intolerance in RA patients was not linked to dosing frequency or administration route, suggesting other factors like age may play a more significant role.

💊 New study finds methotrexate intolerance in RA isn’t significantly affected by dosing route or frequency.
Full article ➡️ www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #Methotrexate #RA #PatientCare #ClinicalResearch

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