Why Gen Z HPV Vaccination Intentions Stall Vaccine perceptions predicted HPV vaccination intentions more strongly than emotional messaging in Gen Z students. Read more.

Vaccine perceptions predicted HPV vaccination intentions more strongly than emotional messaging in Gen Z students.

Read more: www.emjreviews.com/en-us/amj/mi...

Stem Cell Therapies Show Promise For Silicosis Stem cell therapy shows promise for silicosis by targeting fibrosis, immune imbalance, and lung function decline.

Stem cell therapies could open a new chapter in silicosis care. Emerging research suggests these approaches may target key fibrotic and inflammatory pathways...

Read on: www.emjreviews.com/en-us/amj/re...

Respiratory Biologics Underprescribed in Obesity-Linked Asthma Respiratory biologics were prescribed to few eligible patients with obesity and asthma; read more to learn outcomes.

Respiratory biologics are underused in asthma with obesity, despite fewer exacerbations when prescribed.

Care gap: identify eligible patients earlier and cut access delays.

www.emjreviews.com/en-us/amj/rh...

Botulinum Neurotoxin Injection Improves Sleep in Cervical Dystonia Prospective cohort finds botulinum neurotoxin injection improved sleep quality in cervical dystonia, with no significant mood change.

In cervical dystonia, non-motor burden like poor sleep can shape daily quality of life. Real-world cohort results now suggest botulinum neurotoxin injections improve sleep quality even if anxiety and depression don’t shift.

Read on to see what this means:
www.emjreviews.com/en-us/amj/ne...

Sleep Apnea Hypoxic Burden Signals Postop Risk Higher sleep apnea specific hypoxic burden was linked to increased 30-day mortality and cardiovascular complications after major noncardiothoracic surgery.

📊 Elevated sleep apnea-specific hypoxic burden at diagnosis predicts significantly higher 30-day post-operative mortality and cardiac complications after major non-cardiothoracic surgery.

👉 www.emjreviews.com/en-us/amj/re...

@amjreviews.bsky.social #AMJRespiratory

ESMO 2025 Highlights in Non-muscle-Invasive Bladder Cancer The therapeutic landscape in non-muscle-invasive bladder cancer (NMIBC) is advancing with the investigation of new treatment...

#ESMO 2025: The POTOMAC study revealed a ~32% reduction in recurrence in high-risk NMIBC with durvalumab + BCG vs BCG alone, while another PD-L1 combo didn’t show benefit.

What does this mean for care?

www.emjreviews.com/en-us/amj/on...

The publication of this article was funded by AstraZeneca.

Global 2030 Goals Lag for Skin Neglected Tropical Diseases Global DALY trends suggest most countries are not on track to meet 2030 skin NTD SDG targets.

Global progress toward 2030 goals for skin neglected tropical diseases is largely off track.

A new analysis projects major regional inequality, limited countries meeting targets, and a rising disability burden for multiple skin NTDs, with uneven trends.

www.emjreviews.com/en-us/amj/de...

2025 Round-Up: Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer Treatment of early breast cancer (eBC) is continuing to advance, and pivotal Phase III trial data released at the San Antonio Breast...

HER2-positive early breast cancer continues to evolve.

This 2025 round-up explores the latest data on adjuvant therapy, risk stratification, and emerging approaches.

Full symposium coverage: www.emjreviews.com/en-us/amj/on...

The publication of this article was funded by AstraZeneca.

Cervical Cancer Screening Disparities in U.S. Immigrants Systematic review identifies key barriers and promising interventions to address cervical cancer prevention gaps for African-immigrant women.

Cervical cancer screening disparities persist for African-immigrant women in the U.S., shaped by language discordance, lack of insurance, and low HPV awareness. Culturally responsive interventions and HPV self-sampling may help improve uptake.

Read: www.emjreviews.com/en-us/amj/on...

Dancing Linked to 76% Lower Dementia Risk Frequent dancing was linked to lower dementia risk in older adults followed over many years.

🪩 Brain health, with a beat: in a long follow-up study, dancing more than once a week was linked to 76% lower dementia risk. Movement plus coordination and memory, often with social connection.

www.emjreviews.com/en-us/amj/ne...

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Mobile Instant Messaging for Smoking Cessation Falls Short Cluster RCT finds mobile instant messaging exercise reminders did not significantly boost lab-verified smoking cessation at 6 months.

📱🚭 Digital support under scrutiny: In a community-based cluster RCT, instant messaging with brief exercise prompts added to usual smoking cessation advice did not significantly improve biochemically verified abstinence at 6 months.

www.emjreviews.com/en-us/amj/re...

Fast Five: Rheumatology in the Next Decade In this Fast Five, Christine Peoples shares what she’s most excited about in rheumatology and the biggest shifts shaping patient care...

What will rheumatology look like in 5–10 years? In this Fast Five, Dr Christine Peoples shares where patients’ needs are still being missed, and the biggest challenges and opportunities shaping care + thoughts on mentorship, leadership, and healthcare delivery.

www.emjreviews.com/en-us/amj/rh...

Long-Acting Injectable ART Preferences Emerge Interviews in Pakistan highlight what people with HIV want from long-acting injectable antiretroviral therapy and what may block uptake.

💉🧩 Interviews: long-acting HIV shots looked attractive for fewer pills and more privacy. Concerns: side effects, clinic waits, access.

www.emjreviews.com/en-us/amj/mi...

#AMJMicrobiology #HIV

Smoking And Quitting Behaviors Vary by Socioeconomic Position Socioeconomic disadvantage was linked to higher smoking, higher addiction, and lower motivation to quit in England.

📖 Editor’s News Pick: Smoking and quitting behaviors vary by socioeconomic position. A new study suggests how to tailor cessation conversations and pathways so support meets patients where they are.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #ATS

Seborrheic Dermatitis: New Pathophysiology Evidence and Therapeutic Implications Deepen your proficiency in diagnosing and treating seborrheic dermatitis with recent findings about the science behind this disease...

New @amjreviews.bsky.social infographic: Seborrheic dermatitis update, immune activation, barrier/lipid disruption, and microbiome shifts linked to disease.

www.emjreviews.com/en-us/amj/de...

This infographic publication has been supported by a Medical Education Grant from Arcutis Biotherapeutics.

Roflumilast for Psoriasis Shows Early Benefit Meta analysis suggests roflumilast improves early psoriasis outcomes versus placebo and is generally well tolerated, though more trials are needed.

In psoriasis trials, roflumilast delivered higher rates of Investigator’s Global Assessment success vs placebo at Weeks 4 and 8, with a favorable tolerability profile, signaling promise as an effective treatment option.

Details: www.emjreviews.com/en-us/amj/de...

COVID-19 Shifted Pediatric Flu Hospitalization Patterns in Children Study of 553 hospitalized children shows COVID-19 altered pediatric influenza seasonality, influenza A share, and length of stay.

Pediatric influenza hospitalizations have shifted after the COVID-19 era: altered seasonal peaks, a mix of influenza types, and modestly shorter stays.

None of the affected children were vaccinated = a clear call for stronger routine immunization strategies.

www.emjreviews.com/en-us/amj/mi...

Melanocyte Mysteries Uncovered: Interview with David Fisher Interview with David Fisher, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA...

In this expert interview, Dr David Fisher explores key melanocyte mysteries: the surprising link between UV and endorphins, molecular drivers of pigment-related melanoma risk, and where melanoma prevention and treatment are headed.

www.emjreviews.com/en-us/amj/de...

@harvardmed.bsky.social

How Can Hematologist-Oncologists Tackle Invasive Fungal Infections? Expert Insights from Clinical Practice Expert insights from Dr Hana F. Safah on treating invasive fungal infections in hematology/oncology patients...

📢 In hematology/oncology, invasive fungal infections are increasingly frequent and hard to spot early. This interview highlights new risk factors and gaps in rapid diagnosis and future solutions.

Read more: www.emjreviews.com/en-us/amj/mi...

The publication of this article was funded by Astellas.

Time-of-Day Immunochemotherapy Improves NSCLC Survival Earlier infusions improved PFS and OS in advanced NSCLC in a Phase 3 trial.

⏰🫁🔬 NSCLC Phase 3: first 4 immunochemo cycles before 3pm linked to longer survival, with similar safety and a CD8 activation signal.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #NSCLC #LungCancer

Vunakizumab Discontinuation Predicts Plaque Psoriasis Remission After vunakizumab discontinuation, PASI maintenance varied; BMI, interruptions, and psoriasis duration predicted relapse.

🧴🔎 20 weeks after stopping: ~73% near-clear; ~45% fully clear. Treatment interruptions and higher BMI were linked to losing response.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #Psoriasis

Do GLP-1 Receptor Agonists Raise Chronic Cough Risk? GLP 1 receptor agonists were associated with higher incident chronic cough in adults with type 2 diabetes, with risk persisting even after excluding patients with reflux diagnoses.

😮‍💨🩺 GLP-1s linked to chronic cough.

EHR data (T2D): ~12% higher risk vs other meds. Signal remained after excluding reflux (not causal).

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #Pulmonology

Mini-Clinical Evaluation Exercise Improves Resident Self-Assessment Mini-CEX self-assessment training with feedback improved dermatology residents’ clinical performance and strengthened alignment between resident and faculty ratings across multiple evaluation domains.

📊 Dermatology residents showed better self-assessment accuracy and stronger exam performance after structured mini-CEX training with feedback.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #MedicalEducation #ClinEd

Home-Based Video Exercise Program After Lumbar Surgery A home-based video-guided exercise programme improved long-term disability, function, and fear of movement after lumbar spine surgery, with early reductions in depressive symptoms versus standard care...

🎥🧠 Home video-guided exercise after lumbar surgery was linked to lower disability and less fear of movement over 24 months. QoL improved too.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Rehab

Rethinking Early Intervention in Relapsing Multiple Sclerosis: A Closer Look at Long-Term Safety and Efficacy Data for Sphingosine 1-Phosphate Modulators Expert insights on the open-label DAYBREAK study of ozanimod for early relapsing MS: efficacy, long-term safety, and real-world use from...

📖 Long-term data on ozanimod informs relapse reduction, MRI lesion control, and safety considerations clinicians should know.

www.emjreviews.com/en-us/amj/ne...

#MultipleSclerosis #Neurology #AMJNeurology

This article was sponsored by Bristol Myers Squibb and is intended for US neurologists only.

HIV Post-Exposure Prophylaxis Guidance Updated Updated HIV post-exposure prophylaxis guidelines introduce new PEP regimens, shorten follow-up HIV testing, and refine management after occupational exposure when source patients have undetectable vir...

🧬 Updated HIV PEP guidance trims follow-up testing & reflects undetectable viral loads in occupational exposures.

www.emjreviews.com/en-us/amj/mi...

#AMJNeurology #HIV #PEP #InfectiousDiseases

Health Risks Signal Where Prevention May Matter Most A Danish population study linked Health Risks to 30 chronic conditions, showing stress, obesity, and sleep troubles were most consistently associated, while classic behavioural risks showed weaker pat...

🔍 Which risks drive chronic disease most strongly?
Population data show stress, obesity, and physical inactivity are consistently linked with multiple chronic conditions, outweighing several traditional risk factors.

What this may signal for prevention 👇

www.emjreviews.com/en-us/amj/ne...

Social Factors Shape Lung Cancer in Never-Smokers Chronic lung disease and socioeconomic factors were independently linked to higher lung cancer risk in never-smokers, highlighting the need for multifactorial risk assessment beyond smoking history.

🫁📊 Never-smoker NSCLC: chronic lung disease linked to ~3× higher odds. Living outside the capital city also showed higher odds.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #LungCancer

Acne Incidence in Transgender Individuals After Testosterone Acne incidence rose sharply in transmasculine transgender individuals after testosterone, with moderate to severe cases also increasing. Clinicians should monitor closely, especially in the first year...

🧪 New cohort data examine acne incidence after testosterone therapy in transgender individuals

The study reports a rise in acne following testosterone initiation, and differences compared with cisgender cohorts over time.

www.emjreviews.com/en-us/amj/rh...

#Acne #TransgenderHealth