Immunological drivers of zoonotic virus emergence, evolution, and endemicity: Immunity www.cell.com/immunity/ful...

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Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness Mammary intraepithelial lymphocytes enhance mammary gland differentiation during pregnancy, thereby promoting offspring fitness.

Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness: Cell www.cell.com/cell/fulltex...

Structural insights into tecovirimat antiviral activity and poxvirus resistance - Nature Microbiology Tecovirimat forces dimerization of the poxvirus phospholipase F13 blocking virus spread. Clinical monkeypox virus strains resistant to tecovirimat show mutations in the F13 dimer interface.

Congrats to Pablo Guardado-Calvo and colleagues for the analysis of anti #monkeypox virus activity of #tecovirimat, which acts as a molecular glue, triggering dimerization of the #poxvirus F13 protein.
www.nature.com/articles/s41...

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Antiviral activity of tecovirimat against monkeypox virus clades 1a, 1b, 2a, and 2b

Tecovirimat is active in cell culture against all clades of monkeypoxvirus:

www.sciencedirect.com/science/arti...