Unlocking the surfaceome at nanoscale precision.
Discover how Microscoop® + Synlight-Rich & Synlight-Pure enable high-specificity, in situ proteomics for biomarker and target discovery.
📍 Poster #7693 | Board 17 | Poster Section 39
🗓 Apr 22, 9:00 AM – 12:00 PM
We’re presenting at AACR 2026. Poster #7692 shows microscopy-guided photo-biotinylation for spatial proteomics of immune synapses, capturing proteins at cell interfaces.
Combining imaging, ML-defined ROIs, and in situ labeling reveals synapse protein networks missed by conventional methods.
Stop by Booth 2016 at #AACR to meet the team and learn how Microscoop® is enabling:
🔬 Surfaceome discovery like never before
🧬 Mechanistic insights at the nanoscale
🧪 Proteomic insights from FFPE, clinically relevant samples
Looking forward to seeing you!
Key mechanisms in tumor progression, immune response, and therapy resistance occur within nanoscale protein networks—often beyond conventional methods.
Syncell Microscoop® enables microscopy-guided proteomics in FFPE tumor tissue, capturing protein networks where biology happens.
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Cilia are highly diverse across cell types and tissues. Journal of Cell Science highlights the need to profile individual cilia proteomes.
Spatial optoproteomics (Syncell’s Microscoop) maps this complexity by converting visual phenotypes into proteomes.
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Join VIB’s Tech Watch Core as they share a real-world evaluation of Syncell’s Microscoop Mint—tested across diverse samples and research applications.
From platform chemistry to workflow integration, learn what it takes to move from concept to confident implementation.
Register here:
From Alzheimer’s plaques to cardiac amyloidosis, mapping proteins within these structures is unlocking new insights.
Our blog explores how spatial proteomics helps researchers ask not just what proteins are involved, but where they drive disease.
www.syncell.com/blog/reachin...
Primary cilia proteomes are hard to resolve due to size and heterogeneity. Emerging in situ proteomics is changing that, enabling spatially precise, tissue-specific ciliary profiling and new insights into signaling and ciliopathies. www.syncell.com/application-...
Heading to AACR Annual Meeting this year? We’d love to connect!
Discover how Microscoop enables microscopy-guided, nanoscopic proteomics to map protein networks in precise regions—capturing spatial biology beyond conventional methods, including FFPE tumor tissue.
📍 Booth #2016
A recent ChemBioChem review wonderfully summarized recent advances in spatial proteomics, covering both targeted and untargeted methods in this field. Among them, the authors highlight photolabeling-based imaging approaches, including Syncell’s Microscoop technology.
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We’re excited to welcome two new distribution partners in Asia. Spinco Tech supports researchers in India, and SinSage Technology serves scientists in China, expanding access to spatial proteomics tools and local expertise for nanoscale biology research. Learn more: lnkd.in/gzbevJF4
In this Tell Us What You Know episode from Drug Discovery News, CEO & Founder Jung-Chi Liao explains how emerging spatial proteomics technologies help link molecular function to cellular structure, advancing disease understanding and drug discovery.
Watch: www.drugdiscoverynews.com/the-promise-...
🔔 Reminder: Join our upcoming webinar!
🔬 Why are some synapses more vulnerable to neuroinflammation?
Join Chun-Wei Chen (UMass Chan) on March 24 to see how Microscoop® nanoscopic proteomics uncovers neuron-specific programs driving synapse loss.
▶️ Register: lnkd.in/gFARmhkG
Mass spec–based spatial omics is evolving fast — optoproteomics pushes it further. Image-guided, light-activated labeling enables proteome profiling in defined subcellular regions, even FFPE tissue.
New review: advancing TME & biomarker discovery.
link.springer.com/article/10.1...
New interview: how Leibniz Institute for Molecular Pharmacology (FMP) is using Microscoop to bring image-guided precision to discovery proteomics.
From synapse subtypes to organelle proteomes, researchers can define ROIs visually and profile them with MS. www.syncell.com/blog/where-d...
Mechanistic biology isn’t just about identifying proteins — it’s about understanding where they function. Our latest blog explores how high-precision targeting within intact cells can refine proteomic discovery and support clearer mechanistic insight.
www.syncell.com/blog/webinar...
What makes some synapses vulnerable — and others resilient — to neuroinflammation?
Join Chun-Wei Chen (UMass Chan Medical School)
🗓March 24 | 1 PM ET
Using Microscoop to uncover neuron-specific programs driving synapse loss in multiple sclerosis. zoom.us/webinar/regi...
Excited to celebrate the installation of a Microscoop system at ONCOCROSS Co., Ltd with Dr. Jong-Bae Park and team.
Dr. Saewhan Park shared:
“David’s training was fantastic! We’re excited to explore LC-MS–based spatial proteomics, uncover subcellular insights, and deliver visually stunning data.”
Syncell collaborated with Thermo Fisher Scientific to develop a poster for the upcoming US HUPO Conference. Presented by Azad, it features a workflow for profiling ciliary proteomes using the Microscoop® platform with the Orbitrap Astral mass spectrometer for precise nanoscale mapping.
Join us at the US HUPO Conference! We’ll present two posters, and our Head of Product Management, will give a lightning talk on overcoming key limits in cell-surface protein profiling. The workflow enables targeted labeling, followed by enrichment, and LC–MS/MS for precise surface proteome analysis.
As we welcome the Year of the Horse, we celebrate speed, strength, and resilience — qualities that fuel discovery and innovation.
At Syncell, we bring that spirit to nanoscopic proteomics, revealing cellular landscapes faster and with greater precision. fore. Happy Lunar New Year! 🐎✨
What if nanoscale protein interactions could reveal new biomarkers and drug targets in the toughest biology?
At the 2026 PBDD Summit, we partnered with Microscoop and Synlight-Pure to present surfaceome advances, showing how 25 nm precision speeds precision medicine in complex biology.
Condensate biology is entering a new era. Our latest blog shows how microscopy-guided protein purification with Syncell’s Microscoop® enables in situ photolabeling at 25 nm precision—unlocking proteomes of nuclear and cytoplasmic condensates across stress and disease.
This February, our team came together for Wěiyá — a traditional Taiwanese year-end feast held according to the lunar calendar to honor employees and teamwork.
We welcomed the new zodiac year with laughter, great food, prizes, live saxophone, singing, and fun activities.
Exciting times at the Max Planck Institute of Biochemistry in Matthias Mann’s lab!
Dr. Mann’s team is exploring subcellular spatial proteomics, combining visual guidance with nanoscale proteomics to study disease-related proteins and key pathways. We look forward to discoveries with #microscoop!
When membrane biology is dynamic and fragile, nanoscale proteomic purification makes a difference.
We will attend the Keystone Symposia on membrane dynamics and autophagy, focusing on shared mechanisms such as ATG8/LC3 conjugation in disease.
At the 2026 Proteomics-Based Drug Discovery Summit in Boston, discover how nanoscale proteomics uncovers new biomarkers and targets—even in challenging biology. Learn how Syncell’s #Microscoop enables high-throughput spatial proteomics with 25 nm precision to accelerate drug development.
Biomolecular condensates are everywhere—but much of their makeup is still a mystery. 🧩
Microscoop uses nanoscopic proteomics for unbiased, in situ profiling, revealing low-abundance proteins and new insights into signaling, cancer & neurodegeneration. 🔬✨
We’re excited to welcome Chris as our Regional Business Leader, Americas 🎉
With 18+ years in life sciences, Chris has built strong technical sales and customer success teams, turning innovation into customer value.
We’re excited to welcome him as Syncell expands across the Americas.
Astrocytes may look similar—but their proteomes differ. 🧠✨
Using Microscoop® Mint, we compared mouse cortex and hippocampus astrocytes, revealing region-specific proteomic signatures.
👉 Watch Matteo Cattaneo explain how spatial proteomics uncovers the invisible.
vimeo.com/1156938415
