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Exciting times at the Max Planck Institute of Biochemistry in Matthias Mann’s lab!

Dr. Mann’s team is exploring subcellular spatial proteomics, combining visual guidance with nanoscale proteomics to study disease-related proteins and key pathways. We look forward to discoveries with #microscoop!

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At the 2026 Proteomics-Based Drug Discovery Summit in Boston, discover how nanoscale proteomics uncovers new biomarkers and targets—even in challenging biology. Learn how Syncell’s #Microscoop enables high-throughput spatial proteomics with 25 nm precision to accelerate drug development.

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Uit een sedimentmonster van 25 mtr diepte uit de Nieuwe Meer. Dan zie je ineens onder de #microscoop een vette diatomische glimlach! En wat voor een! Ik vermoed #Cymbella #diatoms #kiezelwier #microscopy #freshwater #plankton

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Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism Mitochondria-lipid droplet (LD) interactions play a critical role in lipid metabolism and the progression of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). However, the dynamic ...

Using Microscoop®, we investigated protein interactions in nanoscale contact zones between lipid droplets and mitochondria, revealing key drivers of disease progression in NAFLD/MASH.

Full study → www.biorxiv.org/content/10.1...

#Microscoop #SpatialProteomics #NAFLD #MASH #BioRxiv

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1 schep water uit de plas kleurt prachtig groen.

1 schep water uit de plas kleurt prachtig groen.

Poeppakketje van een roeipootkreeft, wat volgepakt zit met eencellige algen?

Poeppakketje van een roeipootkreeft, wat volgepakt zit met eencellige algen?

Poeppakketje nog aan een inmiddels dode roeipootkreeft.

Poeppakketje nog aan een inmiddels dode roeipootkreeft.

#Ottersaat op Texel. @natuurmonumenten.bsky.social Veel #slobeenden en #smienten. Het water is glasgroen. Een schep genomen en onder de #microscoop gelegd. De samengepakte eencellige algen worden pas zichtbaar in de poeppakketjes van de vele #roeipootkreeftjes. De algen zijn ca 1 Micron groot.

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With Microscoop®, researchers can go beyond assumptions to reveal novel proteomes across organelles, cells, and even whole organisms. By isolating proteins directly in their spatial context, Microscoop uncovers hidden molecular players that drive biology and disease.
#SpatialProteomics #Microscoop

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Ghostly glows, mysterious patterns, and hidden worlds beneath the microscope... 👻🔬

At Syncell, we uncover the unseen — no tricks, just scientific treats.

Happy Halloween! 🎃
#SpatialProteomics #Microscoop #Halloween2025

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Syncell’s Microscoop® can be used seamlessly with FFPE tissue, fresh frozen samples, or fixed cells—empowering unbiased spatial proteomics across diverse sample types.

#SpatialProteomics #Microscoop #Syncell #BiotechInnovation

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🔬 With advanced subcellular resolution, Syncell’s Microscoop® pushes beyond traditional proteomics—isolating proteins from the smallest and most delicate structures, with even finer resolution on the horizon.

#SpatialProteomics #Microscoop #HighResolution #Syncell

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#Microscoop Mint can label cells or organelles with photobiotinylation in fractions of a second. Below shows stress granules at 40X resolution being photo-labelled in real-time!

We can biotin tag all the proteins contained in these organelles and discover and identify all the proteins using LC/MS.

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🚀 Heading to EMBL: Spatial Biology – the Melting Pot this October?
Don’t miss Syncell’s talks on how Microscoop® is transforming spatial proteomics with truly unbiased, hypothesis-free discovery.

#SpatialProteomics #Microscoop #SpatialBiology #EMBL2025

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Microscoop® enables spatial proteomics at the highest resolution—helping researchers uncover more disease-relevant targets faster, with subcellular precision and without prior assumptions.

#SpatialProteomics #DrugDiscovery #Microscoop

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Map organelle proteomes with subcellular precision.From cilia, mitochondria, to endsomes and more, Microscoop® offers unparalleled insights into organelle-specific proteomes.

#SpatialProteomics #OrganelleBiology #Microscoop

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Reprint-GW25007Syncell | GenomeWeb

Syncell in the Spotlight!
Featured in GenomeWeb, our Microscoop platform is redefining spatial proteomics with unbiased protein discovery at subcellular resolution.
📄 Read the full reprint: genomeweb.com/Reprint-GW25...

#SpatialProteomics #ProteinDiscovery #Microscoop #Syncell

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Oedogonium spec.

Oedogonium spec.

Oedogonium spec.

Oedogonium spec.

Het blijft mooi om te zien hoe de natuur zich kan aanpassen.
Deze groene alg (Oedogonium spec.) heeft een speciale cel die zich kan hechten aan bijvoorbeeld de bodem of planten. Zo kan de alg groeien zonder rond te drijven in het water.
#StrabrechtseHeide #Staatsbosbeheer #microscoop

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#Microscoop, reveal distinct proteomic signatures of astrocytes between the cortex and hippocampus—unbiased, spatially resolved, and directly from fixed tissue. We validate these markers that are differentially expressed based on anatomical location. www.syncell.com/application-...

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Natuurwerkavonden in het Natuurhus Natuurwerkavonden in het Natuurhus

Natuurwerkavonden in het Natuurhus

#natuurhusalmelo #mos #natuur #deskundige #knnv #microscoop #almelo #wierden #harbrinkhoek #mariaparochie #aadorp #enter #bornerbroek #tubbergen #twenterand #borne #hertme #zenderen

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😹😹 Iz gon goes chek if dey #tellyscoop an #microscoop dere yett.....

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herr onda syde ob cawshun 😹

#tellyscoop an #microscoop

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Ohkai dat grate, waz worrid #tellyscoop an #microscoop wern rite 😹😽

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iz comfirm tellyscoop #tellyscoop an microscoop #microscoop 😹

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😹 Yezz! Butt jus two comfurm dats #tellyscoop an #microscoop yezz? 😸

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yuoz meenin #tellyscoop 😹an #microscoop 😹

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😹 Yezz George! Iz finkin weez knead dem inn evy poste weez mayk!

#tellyscoop #microscoop 😸

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Microscoop is live in Nijmegen!
A big thank you to the Roepman Lab and the Syncell team for an exciting and productive week of installation, training, and scientific exchange!
From biovalidation to imaging and seminar discussions, the enthusiasm was contagious.
#Microscoop

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Do astrocyte proteomes differ across brain regions?

With Microscoop®, photo-biotinylate and compare astrocytes in the cortex vs. hippocampus—revealing region-specific markers and protein-based subtypes.

syncell.com/wp-content/u...

#SpatialProteomics #Glia #SingleCell #Microscoop

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We just completed a successful #Microscoop installation at Stowers Institute! We’re excited to support the team in their biomedical #research endeavors. Can’t wait to see how Microscoop’s #proteomics discovery capabilities impact your research!
#Proteomics #SpatialProteomics

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Hear Dr. Jung-Chi Liao’s journey from engineering to spatial proteomics using light-triggered biotinylation + 2P microscopy with Microscoop.

Watch on demand: syncell.com/optoproteomi...
Thanks to our host Lynn Spruce!

#Microscoop #SpatialProteomics #Proteomics #Research

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Our Preferred Partner Network is growing! Welcome distributors Agentek in Israel & TrendBio in Australia. Learn more about our Preferred Partner Network: www.syncell.com/preferred-pa... #SpatialProteomics #proteomics #Microscoop #biotech #lifescience #innovation

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Join our CCO Nikhil Rao, PhD at AP-SciBio 2025 in Bangkok, Thailand!
📅 Friday, 6/20
🕚 11-11:50 am
💡Study of whole cell proteome- the proteomic difference of astrocyte between mouse brain cortical and hippocampal regions
#Syncell #Microscoop #Proteomics #SpatialProteomics

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