Antibody-mediated feedback modulates interclonal competition in the germinal center Antibodies generated by prior immune responses regulate B cell responses upon recall immunization. Barbulescu et al. examine whether antibodies produced by an ongoing immune response influence the out...

One more trick pulled off by antibody-mediated feedback

www.cell.com/immunity/ful...

Congratulations, Benjamin!

Congratulations, Amelia!

Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8

Antibody-mediated feedback modulates interclonal competition in the germinal center Serum antibodies from prior immune responses regulate B cell activation and germinal center (GC) access upon recall immunization. However, how antibodies produced by an ongoing immune response influen...

Check out our latest preprint on the effects of antibody-mediated feedback on ongoing germinal center reactions, led by Alex Barbulescu and @janabilanovic.bsky.social

www.biorxiv.org/content/10.1...

Incredible honored to receive this award! Thank you Blavatnik and New York Academy of Science

Congratulations Ciça! Very well deserved!!

Excited to share our new preprint! We studied how T cells are functionally & clonally shaped across organs over time. With the new TRACK mice, we genetically label recently activated T cells with tdTomato and track their migration across tissues. #immunology #science www.biorxiv.org/content/10.1...

Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception Regulatory T cells curb noxious sensory signaling to dampen cutaneous inflammation, a neuromodulatory mechanism for immunosuppression.

After many years of work I’m so happy to share our work on #scienceimmunology on how Treg cells modulate nociception to dampen skin inflammation! My handle will make a lot more sense now!🕵🏻‍♀️

Replaying germinal center evolution on a quantified affinity landscape Darwinian evolution of immunoglobulin genes within germinal centers (GC) underlies the progressive increase in antibody affinity following antigen exposure. Whereas the mechanics of how competition be...

Wanted to highlight our latest preprint--a huge effort by multiple people and labs, but led primarily by @wsdewitt.github.io, Tatsuya Araki, and Ashni Vora, in a very close wet-dry collaboration with @matsen.bsky.social’s lab at the Hutch

www.biorxiv.org/content/10.1...

Cool germinal center acrobatics from Juhee Pae et al, check it out!

www.nature.com/articles/s41...

Thank you!!

Congratulations, Olivia!!

Honored to be named an HHMI Fellow of the Damon Runyon Cancer Research Foundation among these amazing scientists! Very grateful for the support for my postdoctoral research in the Rudensky lab @mskcancercenter.bsky.social!
@damonrunyon.org @hhmi.org

Terminal differentiation and persistence of effector regulatory T cells essential for preventing intestinal inflammation @natimmunol.bsky.social
www.nature.com/articles/s41...

How Does the Gut Immune System Distinguish Between Friends and Foes? Cell-cell interactions help drive tolerogenic or inflammatory responses to the maelstrom of antigens passing through the gut.

Rockefeller's @cicacanesso.bsky.social talks to The Scientist about her recent work with @danmucida.bsky.social and @victora.bsky.social on how cell-cell interactions help drive tolerogenic or inflammatory responses to the maelstrom of antigens passing through the gut.

Identification of antigen-presenting cell–T cell interactions driving immune responses to food The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal ant...

I am excited to share our study showing how the immune system strikes a delicate balance between tolerating food and defending against helminth infections.
www.science.org/doi/10.1126/....

#Immunology by First release now @science.org

Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection

https://buff.ly/3DjNQ1e

By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.

Congratulations, Djenet!!

Check out our last pub. from @mfgrp.bsky.social al lab! We discovered that skin commensal microbes induce systemic and local B cell responses upon colonization and took advantage of this knowledge to create topical vaccines using engineered skin microbes. Please read the thread for details.

I’m looking for a postdoc to join my group here at Chan Zuckerberg Biohub NY! This position offers the chance to delve deeply into the dynamic and functional behavior of T cells, exploring how their fate decisions shape immune responses in health and disease.

More information at parsalab.science

Gregory P Donaldson, PhD, Assistant Professor at MIMG (starting January 2025) | Microbiology Immunology & Molecular Genetics Please join us as we welcome Dr. Donaldson to UCLA in his new role as assistant professor in the Department of Microbiology, Immunology, and Molecular Genetics.

Goin back to Cali. Find me at UCLA. I’m recruiting at all levels. You can learn more at our lab website: www.donaldsonlab.com

We have an advertisement up for a technician (SRA) position:
jobs.ucla.edu/jobs/5998