Long-read sequencing of Mycobacterial tuberculosis is comparable to short-read sequencing for antimicrobial resistance prediction and epidemiological studies. www.biorxiv.org/content/10.64898/2026.04...
Posts by Philip Fowler
Somehow I missed this on #WorldTBDay earlier in the week but it is so good I have to repost it.
Check out this comic on “A World without Tuberculosis”
bobthesquirrel.art/copy-of-un-m...
On #WorldTBDay, it’s important to reflect on the scale of the challenge we’re facing.
In 2024 alone, tuberculosis (TB) caused 1.23 million deaths worldwide, remaining the leading cause of death from a single infectious agent, according to WHO
@ndm.ox.ac.uk
@wvschaik.bsky.social introducing the Black Knight model for identifying ARGs at #AMR2026.
A defining moment or at least an excellent use of a Monty Python analogy. The field needs more off the wall thoughtful comments!
Since 2017 the CRyPTIC project collected and collated 53,897 clinical TB samples with genetics and drug susceptibility testing data.
You can download the datasets via crypticproject.info and v4.0.0 will appear later this year.
#WorldTBDay @modmedmicro.bsky.social
@zaminiqbal.bsky.social giving an uplifting talk at #AMR2026.
As ever he makes me think. 🤔
#AMR2026 about to kick off at the #wellcome genome campus! Got here a bit early so went to visit the new Thornton Building.
Rare opportunity to apply to become a President of Oxford’s newest college!
www.nature.com/naturecareer...
I saw @reduced.bsky.social at the Rep in Bham when I was 17 in 1993.
Took my daughters to see the same in Chipping Norton today.
Better than I remember it. And my eldest is? 17
Thanks Jenny! Yep on my second department and was looking back though my file and found at least 8 “your contract has been extended” letters. Still worth it for the bonus annual leave.
20 years ago today I started as a Postdoc at @ox.ac.uk on a six month contract and somehow am still here! 🤯🥳
Our team wore blue for World Antimicrobial Awareness Week 2025💙
Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance.
#WAAW @oxfordbrc.bsky.social
For #WorldAntimicrobialAwarenessWeek, we introduce our recent paper on antibiotic-resistant subpopulations in TB.
TB may be one of humanity’s oldest diseases, yet it still kills over 1M people yearly. As resistance spreads, knowing each patient’s resistance profile before treatment is vital. 🧬💊
Antimicrobial resistance occurs when bacteria, viruses, fungi & parasites change over time - leading to medicines being less effective against them.
Here you see bacteria growing and antibiotics (the small discs) which kill the bacteria...unless they are resistant!
#WAAW #AMR @oxfordbrc.bsky.social
Are you interested in infections, the micro-organisms that cause them and antimicrobial resistance? So are @bashthebug.net and they're looking for new members to join their patient & public group. More info: bashthebug.net/lay-represen... Deadline 27 Nov @ouhospitals.bsky.social @medsci.ox.ac.uk
New paper by @vbrunner.bsky.social looking at detecting rifampicin resistant subpopulations in M. tuberculosis infections using genetics and putting a lower limit on the proportion that arose due to secondary infections.
bit.ly/47rwf42
@modmedmicro.bsky.social
@oxfordbrc.bsky.social
Pleased to see this pre-printed, highlighting the completeness/accuracy of @nanoporetech.com long-read genome assembly for clinical Enterobacterales: www.biorxiv.org/content/10.1...
Thanks to colleagues @modmedmicro.bsky.social, @ukhsa.bsky.social, @genewiz.bsky.social and @oxfordbrc.bsky.social!
Great new work from #DotNagy @modmedmicro.bsky.social - she tool 96 clinical isolates from the NEKSUS study and sequenced with both Illumina and Nanopore - question was, can we do away with hybrid sequencing for the rest of the study?
www.biorxiv.org/content/10.1...
'Linking life expectancy to the bacteria in our gut: A final year undergraduate project'.
Akika investigated how the gut microbiome influences longevity, with fieldwork in Nagano, Japan—home to the country’s longest-living population.
Read the blog post here ➡️ bashthebug.net/2025/08/22/l...
I’ve just watched all of MurderBot and definitely recommend
Brilliant! Yes a timeless test which stops on Mondays instead of Sundays
Brilliant - signed up.
Always thought cycling shared with cricket the curious feature that one can listen to someone talking about what is going on (like TMS) and that is perhaps even better than watching it.
The TdF is after all even longer than a Test Match.
Bit over 24 hours left to apply for these two posts to help us develop pipelines to process pathogens..!
Senior Bioinformatic Engineer
bit.ly/4ecl0hF
Senior Biostatistical Researcher
bit.ly/4kRfZxI
Grade 8 or 7, depending on experience
closing date: noon Tues 8 July
Poster illustration showing the back of a bicycle rider riding on the side of a street and running out of room as a truck driver drives so close to the curb as to make the bicyclist lose control.
Mind That Cyclist! Give Him Room
1950
Artist: Roland Davies
Job advert to come and work with me on tuberculosis closes tomorrow (Friday) at noon!
Part of #OxCOD4TB
bit.ly/4ndKOhF
@ndm.ox.ac.uk @modmedmicro.bsky.social
@oxfordbrc.bsky.social
Congratulations to the winners of the poster prizes, Elliott Rogers and Iva Grujic, yesterday at the 3rd #Dx4LMIC conference at @reubencollege.bsky.social !
Andrew Singer gets day two underway at the #Dx4LMICs conference at @reubencollege.bsky.social
Lionel Tarassenko introducing Vivian Lee who is giving the after dinner speech at #Dx4LMICs conference at @reubencollege.bsky.social
Jospeth Matovu: HIV self testing among fishermen
@reubencollege.bsky.social #Dx4LMICs
Arjuna Sen talking about equity in epilepsy at @reubencollege.bsky.social
#Dx4LMICs