In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.socialβ¬.
Read now: pubs.rsc.org/en/content/a...
Posts by Sjoerd de Haan
In what situations are tests for plutonium surrogate (CeO) contamination in soil used? Sorry, I could not read. access to article is restricted.
That moment when your "weird" banana-shaped data reveals fundamental crystal physics π€―
Simple UV-vis + quantum sims show gold nanorods grow with coupled dimensions.
scienceandmachines.com/daily/2025-0...
π§ͺ Applied gradient descent to gold nanorod and spectroscopy!
Decomposing UV/Vis absorption into basis functions reveals size distributions with banana-shaped correlations between length/diameter.
Short blog post: scienceandmachines.com/daily/2025-0...
#ML #nanoscience
Just wrote about working with experimental data in Python.
Used real quantum simulation data to show three ways to structure experimental grids.
scienceandmachines.com/data-driven-...
#Chemistry #Biology #Machinelearning
When you have 50 expensive nanoparticle spectra instead of 50,000 cat photos, what do you do?
Suddenly understanding distributions and uncertainty quantification isn't optional. Math matters in scientific machine learning.
scienceandmachines.com/knowledge-ba...
#spectroscopy #machinelearning
Interactive exploration of gold nano rod UV/Vis spectra.
#spectroscopy #nanoscience
scienceandmachines.com/daily/2025-0...
I'm 3 weeks into figuring out: "can machine learning + analytical chemistry impact biotech?"
www.scienceandmachines.com
Tinkering with #spectroscopy plots.
Made a platform for showcasing analytical methods.
#science-data
Going through #spectroscopy data from a paper. Messy as usual.
#science-data
How do you store and process spectrum data?
I need to store, process and display spectra for a demo.
Curious what software others use.
#spectroscopy
Just wrapped a organization's first ML project. Key insight: AI readiness isn't about the tech.
It's about:
π Data-driven decisions
π Systematic evaluation
π§ͺ Experimentation culture
β‘ Speed infrastructure
Master these before AI arrives. Your competitors are waiting. Don't.
Nice Andreas. Do you have plans to start a study with the device? How would that look like?
Development of a low-cost, versatile, #Arduino -controlled #OpenSource #gas #chromatography system for #teaching #analytical #chemistry:
- cost: < US $100
- #Python #GUI
doi.org/10.1021/acs....
#DIYbio #DIYchem #lab #instruments #education #STEM #MINT #school #EDU #GC
UV/Vis spectroscopy + 30 experiments + Extra Trees = predicting gold nanoparticle shapes
Sometimes small data + domain knowledge beats big data + brute force
New post: scienceandmachines.com/daily/2025-07-07/np-synthesis-ml
π° The $2M question in nanoparticle QC: How do you get TEM-quality data without TEM costs?
Today's deep dive revealed why this matters for biotech. π§΅
scienceandmachines.com/daily/2025-0...
Wrote some notes on "Machine Learning Prediction of UVβVis Spectra Features of Organic Compounds Related to Photoreactive Potential.β
scienceandmachines.com/daily/2025-0...
What's the story behind the 96-core AMD? Hobby system with compute for buck?
What is taking up ~ 500 GB memory on your local machine while running DeepSeek-R1?
Week 2 learning chem AI: Natureβs Colored Molecules and the Bathochromic Shift π΅ β π’ β π‘ β π΄ .
Why study as ML person?
The next biotech revolution won't come from better models aloneβit'll come from ML that designs & interprets experiments.
Notes: scienceandmachines.com/daily/2025-0...
From data mining to experiment mining.
2 weeks into studying analytical chemistry, I want to make a prediction.
In 5 years we will not talk about just "models" but about dedicated (equipment + machine learning) experiments.
We will not mine data, but chemistry itself.
π§ͺ Why is ethylene invisible but Ξ²-carotene orange? The bathochromic shift! Extended conjugation moves absorption from UV to visible light, creating color β¨
scienceandmachines.com/daily/2025-0...
#Chemistry #Science #DailyLearning #Spectroscopy
Orbital energies in UV/vis spectroscopy matter for understanding what ML models actually learn
scienceandmachines.com/daily/2025-0...
#Microscope Upcycling: Transforming legacy microscopes into #automated #cloud-integrated #imaging systems:
- #OpenSource automation: X-Y positioning, focus stacking, img acquisition/storage
- cost: US $300
doi.org/10.1016/j.oh...
#DIYbio #lab #instruments #microscopy #Raspi #PiCam #Python #OpenCV
I'm wondering too... so what did you build in those 4 months, using Deepseek?
π§ͺ TIL: Protein crystals mess with uv/vis.
Crystals scatter light, bend it, reflect it - and distort your spectroscopy data.
But here's the cool part: @ncaramel.bsky.social built a Python toolbox that automatically corrects for all the optical shenanigans.
Paper: journals.iucr.org/j/issues/202...
Coming from ML background, trying to understand where UV/Vis + machine learning could make impact in biotech labs.
What papers do UV/Vis practitioners recommend for someone learning the intersection of analytical chemistry + ML in biotech?
#AnalyticalChemistry #UVVis #MachineLearning #Biotech
Production schedule showing for each machine the jobs they are occupied with over time.
Writing diagrams as code with Tikz becomes so much easier with Claude.
And it still takes a lot of time...
Ai4bio conference in delft covered all scales in biotech. Impossible to summarize, this slide comes closest.
#biotech #machinelearning