Advertisement Β· 728 Γ— 90

Posts by Sjoerd de Haan

Preview
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an a...

In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social‬.
Read now: pubs.rsc.org/en/content/a...

8 months ago 16 10 0 1

In what situations are tests for plutonium surrogate (CeO) contamination in soil used? Sorry, I could not read. access to article is restricted.

8 months ago 0 0 0 0
Post image

That moment when your "weird" banana-shaped data reveals fundamental crystal physics 🀯

Simple UV-vis + quantum sims show gold nanorods grow with coupled dimensions.

scienceandmachines.com/daily/2025-0...

8 months ago 3 0 0 0
Post image

πŸ§ͺ Applied gradient descent to gold nanorod and spectroscopy!

Decomposing UV/Vis absorption into basis functions reveals size distributions with banana-shaped correlations between length/diameter.

Short blog post: scienceandmachines.com/daily/2025-0...

#ML #nanoscience

8 months ago 1 0 0 0
Post image

Just wrote about working with experimental data in Python.

Used real quantum simulation data to show three ways to structure experimental grids.

scienceandmachines.com/data-driven-...

#Chemistry #Biology #Machinelearning

8 months ago 3 0 0 0
Post image

When you have 50 expensive nanoparticle spectra instead of 50,000 cat photos, what do you do?

Suddenly understanding distributions and uncertainty quantification isn't optional. Math matters in scientific machine learning.

scienceandmachines.com/knowledge-ba...

#spectroscopy #machinelearning

9 months ago 1 0 0 0
Video

Interactive exploration of gold nano rod UV/Vis spectra.
#spectroscopy #nanoscience

scienceandmachines.com/daily/2025-0...

9 months ago 0 0 0 0
Advertisement
Post image

I'm 3 weeks into figuring out: "can machine learning + analytical chemistry impact biotech?"

www.scienceandmachines.com

9 months ago 0 0 0 0

Tinkering with #spectroscopy plots.

Made a platform for showcasing analytical methods.

#science-data

9 months ago 1 0 0 0
Video

Going through #spectroscopy data from a paper. Messy as usual.

#science-data

9 months ago 1 0 0 0

How do you store and process spectrum data?

I need to store, process and display spectra for a demo.
Curious what software others use.

#spectroscopy

9 months ago 0 0 0 0

Just wrapped a organization's first ML project. Key insight: AI readiness isn't about the tech.

It's about:
πŸ“Š Data-driven decisions
πŸ”„ Systematic evaluation
πŸ§ͺ Experimentation culture
⚑ Speed infrastructure

Master these before AI arrives. Your competitors are waiting. Don't.

9 months ago 1 0 0 0

Nice Andreas. Do you have plans to start a study with the device? How would that look like?

9 months ago 0 0 0 0
Post image Post image Post image Post image

Development of a low-cost, versatile, #Arduino -controlled #OpenSource #gas #chromatography system for #teaching #analytical #chemistry:

- cost: < US $100
- #Python #GUI

doi.org/10.1021/acs....
#DIYbio #DIYchem #lab #instruments #education #STEM #MINT #school #EDU #GC

9 months ago 9 6 1 0
Post image

UV/Vis spectroscopy + 30 experiments + Extra Trees = predicting gold nanoparticle shapes

Sometimes small data + domain knowledge beats big data + brute force

New post: scienceandmachines.com/daily/2025-07-07/np-synthesis-ml

9 months ago 0 0 0 0
Advertisement
Post image

πŸ’° The $2M question in nanoparticle QC: How do you get TEM-quality data without TEM costs?

Today's deep dive revealed why this matters for biotech. 🧡

scienceandmachines.com/daily/2025-0...

9 months ago 0 0 0 0
Post image

Wrote some notes on "Machine Learning Prediction of UV–Vis Spectra Features of Organic Compounds Related to Photoreactive Potential.”

scienceandmachines.com/daily/2025-0...

9 months ago 0 0 0 0

What's the story behind the 96-core AMD? Hobby system with compute for buck?

9 months ago 0 0 0 0

What is taking up ~ 500 GB memory on your local machine while running DeepSeek-R1?

9 months ago 0 0 0 0
Post image

Week 2 learning chem AI: Nature’s Colored Molecules and the Bathochromic Shift πŸ”΅ β†’ 🟒 β†’ 🟑 β†’ πŸ”΄ .

Why study as ML person?

The next biotech revolution won't come from better models aloneβ€”it'll come from ML that designs & interprets experiments.

Notes: scienceandmachines.com/daily/2025-0...

9 months ago 0 0 0 0

From data mining to experiment mining.

2 weeks into studying analytical chemistry, I want to make a prediction.

In 5 years we will not talk about just "models" but about dedicated (equipment + machine learning) experiments.

We will not mine data, but chemistry itself.

9 months ago 0 0 0 0
Conjugation in UV/Vis spectroscopy – Science and Machines

πŸ§ͺ Why is ethylene invisible but Ξ²-carotene orange? The bathochromic shift! Extended conjugation moves absorption from UV to visible light, creating color ✨

scienceandmachines.com/daily/2025-0...

#Chemistry #Science #DailyLearning #Spectroscopy

9 months ago 0 0 0 0
Orbital Energies in UV/Vis Spectroscopy – Science and Machines

Orbital energies in UV/vis spectroscopy matter for understanding what ML models actually learn
scienceandmachines.com/daily/2025-0...

9 months ago 0 0 0 0
Post image Post image Post image Post image

#Microscope Upcycling: Transforming legacy microscopes into #automated #cloud-integrated #imaging systems:

- #OpenSource automation: X-Y positioning, focus stacking, img acquisition/storage
- cost: US $300

doi.org/10.1016/j.oh...
#DIYbio #lab #instruments #microscopy #Raspi #PiCam #Python #OpenCV

10 months ago 14 10 1 0

I'm wondering too... so what did you build in those 4 months, using Deepseek?

10 months ago 0 0 0 0
Advertisement
Preview
Learning with a homemade model insulin pump - Raspberry Pi A diabetic teen created a Raspberry Pi-based medical pump to better understand how insulin doses keep him alive.

www.raspberrypi.com/news/learnin...

10 months ago 1 1 0 0
Preview
The in crystallo optical spectroscopy toolbox The rise of time-resolved macromolecular crystallography has been accompanied by renewed interest in companion biophysical characterization methods applicable to molecules both in solution and in crys...

πŸ§ͺ TIL: Protein crystals mess with uv/vis.

Crystals scatter light, bend it, reflect it - and distort your spectroscopy data.

But here's the cool part: @ncaramel.bsky.social built a Python toolbox that automatically corrects for all the optical shenanigans.

Paper: journals.iucr.org/j/issues/202...

10 months ago 2 0 0 0

Coming from ML background, trying to understand where UV/Vis + machine learning could make impact in biotech labs.

What papers do UV/Vis practitioners recommend for someone learning the intersection of analytical chemistry + ML in biotech?

#AnalyticalChemistry #UVVis #MachineLearning #Biotech

10 months ago 1 0 1 0
Production schedule showing for each machine the jobs they are occupied with over time.

Production schedule showing for each machine the jobs they are occupied with over time.

Writing diagrams as code with Tikz becomes so much easier with Claude.

And it still takes a lot of time...

11 months ago 0 0 0 0
Post image

Ai4bio conference in delft covered all scales in biotech. Impossible to summarize, this slide comes closest.

#biotech #machinelearning

11 months ago 0 0 0 0