A molecular model of a protein, lit up by different coloured lights, sits inside a shiny globular structure.

This image was made in Blender to show how the protein spectrin fits into the pocket of an enzyme complex known as PP1/Phactr1 while undergoing dephosphorylation.

Dephosphorylation, and the reverse process phosphorylation, are key mechanisms in cell signalling pathways.

Postdoc positions open in my lab (Francis Crick Institute) to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

Postdoctoral Fellow - Balchin Lab Salary for this Role: From £43,210 with benefits, subject to skills and experience Job Title: Postdoctoral Fellow - Balchin Lab Reports to: David Balchin Closing Date: 28/Feb/2025 23.59 GMT Job Descri...

We're hiring a postdoc!
Applications from any nationality welcome.
Projects around protein folding in cells, ribosomes, chaperones etc.
4 yr contract, fantastic research environment @crick.ac.uk
crick.wd3.myworkdayjobs.com/External/job...

Merry Xmas and Happy new year 2025!

#sciart #b3d @crick.ac.uk #molecularnodes

True !

I also noticed this, no more spaghettis around a globular domain (AF2) but predicted helices with very bad plddt score (AF3).
This is very confusing for someone who doesn't pay much attention to pLddT scoring!

I really enjoyed the AsCA 2024 meeting in Kuala Lumpur! A lot of great sciences and great people in a great city! @crick.ac.uk

‘A place of joy’: why scientists are joining the rush to Bluesky Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.

Bye Bye X (Twitter)!
Good morning BlueSky!

www.nature.com/articles/d41...

Gale bound to its cofactor NAD
#b3d #sciart #moleculatnodes @crick.ac.uk #b3d

Hidden active site...
#sciart #b3d #molecularnodes @crick.ac.uk

Playing with Blender and #molecularnodes #b3d #sciart
I really like that one...

PP1-Phactr1 Holophosphatase bound to it's substrate... (purple:active site, yellow and green:amphipathic pocket and hydrophobic pocket guiding substrate specificity).

PP1-Phactr1 holophosphatase bound to its substrate iRsP53.
#blender #sciart #molecularnodes

I'm on Brady's discord channel (blender.science) if this is what you ask for?

I couldn't find one so I made one. Scientists who blend starter pack! Follow all the coolest #b3d science renders! I don't know everyone (or really anyone) so self-nominate and I'll add you in! (Bonus points if you post a cool render) go.bsky.app/S253qJN

I'm a Structural Biologist at the Francis Crick Institute in London and I Love blending my structures!!!