Ahead of #WorldDiabetesDay tomorrow, we're delighted to announce new landmark research that uncovers why type 1 #diabetes is more aggressive in young children.
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A picture of Dr Sarah Richardson and assistant in the lab, with text stating 'Groundbreaking research announced - Research funded by the Steve Morgan Foundation uncovers why type 1 diabetes is more aggressive in young children'

We're pleased to share groundbreaking news from the Type 1 Diabetes Grand Challenge!

A research team led by Dr Sarah Richardson has uncovered why type 1 diabetes affects young children differently.

Read more here - bit.ly/4hXDUuJ

#ChangingLivesForGood #Type1DiabetesGrandChallenge

Small things matter: Lack of extraislet β cells in type 1 diabetes Early loss of small extraislet β cells in children with type 1 diabetes could explain age-related differences in disease.

📚 Or check out our new research article, recently released in Science Advances 🔗: doi.org/10.1126/scia...

Small things matter in Type 1 diabetes YouTube video by University of Exeter

Our new research article 🔬 suggests that the maturity of the pancreas at onset of type 1 diabetes may hold the key to understanding why the disease course differs in early vs later life 📈. Watch our video to learn more! Produced in collaboration with @amanigardner.bsky.social

youtu.be/O-Q0e5rEUy4

Registration and abstract submission for IDS Congress 2026 in Brisbane, Australia open September 1, 2025!

www.ids2026.com.au

Don't delay to register and submit an abstract to share your research!

IDS Immunology of Diabetes Society The purpose of the Immunology of Diabetes Society (IDS) is to foster research related to the pathogenesis, prevention, and cure of type 1 diabetes and to provide an international forum for the scienti...

The new Immunology of Diabetes Society website is live! Visit us at
www.immunologyofdiabetessociety.com

A big thanks to Sally Kent and Dirk Homann for spearheading this effort!!

@exeter.ac.uk

Take-home message: We propose that, particularly in young children, type 1 diabetes may be a disease of beta cell loss (driven by more efficient immune-mediated destruction), coupled with a net initial beta cell deficit, resulting from a failure to establish larger islets in sufficient quantities.

Extra-islet single and small clusters of beta cells are virtually absent in individuals with type 1 diabetes and islets that retain beta cells are larger

Development of type 1 diabetes at an early age is associated with fewer large islets in adulthood

We show:
A significant proportion of total pancreatic endocrine area consists of single and small clusters of beta cells which reside outside of typical islet structures

There is a shift towards larger islets with age, with the most pronounced changes occurring in the first few years of life

bioRxiv QR code link to the publication

www.biorxiv.org/cgi/content/...

Thanks to funders:
@breakthrought1duk.bsky.social ky.social
@diabetesuk.bsky.social sky.social
@stevemorganfdn.bsky.social dn.bsky.social

Kudos to the amazing team, especially:
@katymurrall.bsky.social
@teifionluckett.bsky.social
@clekka.bsky.social

A representative spatial plot of endocrine objects in the pancreas, with the colour change reflecting the size of the endocrine objects

Small things really do matter in type 1 diabetes. Exciting work from the Exeter SMF Grand Challenge team provides important insights into why #T1D in children may differ from T1D in adults. Important implications for screening strategies and future treatments. Check out our new bioRxiv paper 👇

Welcome to the new IDS Immunology of Diabetes Society Bluesky account! We are a society dedicated to research of type 1 diabetes with the goal of preventing and curing this autoimmune disease.

The 21st Immunology of Diabetes Society Congress IDS 2026 will be held in Brisbane Australia April 20-24, 2026

We are excited to share that the IDS2026 website is live.
www.ids2026.com.au

Welcome - IDS 2026 The Immunology of Diabetes Society Congress brings together international health care professionals, consumers and research leaders in Type 1 Diabetes. Sarah Richardson Invitation from the IDS Preside...

www.ids2026.com.au

Key dates for the IDS2026 Congress - 20 April 2026:
Registration opens 1 September 2025
Abstract submission opens 1 September 2025
Abstract submission closes 20 January 2026
Abstract notifications 23 February 2026
Earlybird registration deadline 9 March 2026

More information at www.ids2026.com.au

Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue - Diabetologia Aims/hypothesis Previous pathology studies have associated enterovirus infections with type 1 diabetes by examining the enterovirus capsid protein 1 (VP1) in autopsy pancreases obtained near diabetes ...

Joint analysis of nPOD Diabetes pancreas finds multiple markers of #enterovirus infection associated with type 1 diabetes, supporting efforts to prevent #T1D by vaccination and/or antiviral therapy.
link.springer.com/article/10.1... 🔓

Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes - Diabetologia Aims/hypothesis Earlier studies of pancreases from donors with type 1 diabetes demonstrated enteroviral capsid protein VP1 in beta cells. In the context of a multidisciplinary approach undertaken by t...

Enterovirus infections may occur throughout the natural history of type 1 #diabetes and may be associated to islet cell HLA-I hyperexpression. @teresarc.bsky.social @sarahibex.bsky.social #T1D #DiabetesResearch link.springer.com/article/10.1... 🔓