A novel Coxsackievirus B5 vaccine candidate selected via biological properties shows promise for safer immunization.
doi.org/10.15212/ZOO...
#Coxsackievirus #Enterovirus #Vaccines #VaccineDevelopment

New lab paper in PLOS Pathogens!
​We show how enteroviruses use upstream AUGs to modulate protein expression.
I was glad to join the project in its final stages and contribute to the concluding efforts of this great collaboration.
​ #Enterovirus #RNA #Cambridge

#Enterovirus D68 #Sequence #Variations and #Pathogenicity: A Review

#Enterovirus D68 #Sequence #Variations and #Pathogenicity: A Review, etidiohnew.blogspot.com/2026/01/ente...

Broad-spectrum antiviral activity of ebselen - Scientific Reports Broad-spectrum antivirals are essential for pandemic preparedness, helping reduce mortality and mitigate social disruption. Ebselen, a synthetic organoselenium compound, is under investigation for…

Broad-spectrum #antiviral activity of #ebselen ...

| #pandemic | #virus | #infections | #dengue | #Zika | #chikungunya | #Influenza | #enterovirus | Via @nature.com

Australian National Enterovirus Reference Laboratory annual report, 2024.
Bruggink, Leesa et al.
Paper
Details
#Enterovirus #PublicHealth #Australia

Kuukausittaiset rino- ja enterovirustapaukset tartuntatautirekisterin mukaan vuodesta 1996 tämän vuoden lokakuuhun. Data: THL (CC BY 4.0)

Kuukausittaiset rino- ja enterovirustapaukset tartuntatautirekisterin mukaan ja koronaviruksen määrä jätevesissä skaalattuna niin että mahtuvat samaan kuvaan. Ajanjakso tämän vuoden alusta lokakuun loppuun. Data: THL (CC BY 4.0)

Tartuntatautirekisterin kuukausittaiset rino- ja enterovirustapaukset. Koronan jätevesiseurannassa näkyvä tämänsyksyinen jyrkkä lovi osuu sopivasti rino- ja enterovirusepidemiahuipun kohdalle, joten niillä saattaa hyvinkin olla asian kanssa jotain tekemistä.

#KoronaFI #Enterovirus #Rinovirus

1/ 🚀 Exciting news: we’ve just released the first Nextclade dataset for Enterovirus D68 (EV-D68), developed in collaboration with the European Non-Polio Enterovirus Network (ENPEN).

👉🏻 Check out the dataset on Nextclade! clades.nextstrain.org?dataset-name...

#EVD68 #Enterovirus #OpenData

Synergistic combination of orally available safe-in-man pleconaril, AG7404, and mindeudesivir inhibits enterovirus infections in human cell and organoid cultures - Cellular and Molecular Life Sciences Enteroviruses can infect various human organs, causing diseases such as meningitis, the common cold, hand-foot-and-mouth disease, myocarditis, pancreatitis, hepatitis, poliomyelitis, sepsis, and type ...

A multinational research team at NTNU, @fimm-uh.bsky.social, @campathology.bsky.social et al. developed a 3-drug combination that inhibited #enterovirus replication in human cell & #organoid culture, with the potential for treating enterovirus-triggered #T1D.

link.springer.com/article/10.1...

Enterovirus D68 (EV-D68) capsid model A predicted capsid model of EV-D68 prepared by CYTW. Models was prepared using computer programs, DeepView/Swiss-Pdb Viewer v4.1.0 and UCSF Chimera v1.7. Sequences for each capsid peptide were threade...

EV-D68 capsid model (it's only a model, a *prediction*) up under CC BY 4.0; use but cite).
With thanks to ClaireW
(it's quite a few years old now)
#enterovirus #EVD68
figshare.com/articles/fig...

Like many viruses, those in the huge group we call enteroviruses can cause a wide range of diseases.
Each one of these is a pathogen to be respected, and some have not had their stories told yet.
#EV #HEV #enterovirus

Newborn dies of enterovirus - Taipei Times Bringing Taiwan to the World and the World to Taiwan

Newborn dies of #enterovirus ...

| #pathogen | #Taiwan | #death | #infection | #infant | Via @taipei-times.pbs.idv.tw.ap.brid.gy

Coxsackievirus B infection invokes unique cell-type-specific responses in primary human pancreatic islets Veronese-Paniagua et al. demonstrate that coxsackievirus B3 infects all primary human islet cell types and elicits distinct cell-type-specific transcriptional and mitochondrial responses. They identif...

#Medsk🧪 #IDsky #immunosky #Publichealth @cp-cellreports.bsky.social #Enterovirus infection is a long-stipulated environmental trigger for T1D.,,

www.cell.com/cell-reports...
@pnas.org
www.pnas.org/doi/10.1073/...

pmc.ncbi.nlm.nih.gov/articles/PMC...

pmc.ncbi.nlm.nih.gov/articles/PMC....

Thanks Jess! I have no idea what I am doing on here... even less so than Twitter. I'd love to follow more #IDSky so please follow/reach out if you are interested in #pedsID #diagnosticstewardship #enterovirus #EVD68 #EVA71 #acuteflaccidmyelitis #encephalitis #meningitis #pandemicpreparedness

#Medsky🧪 #IDsky #virosky #pedsky #immunosky #Neurosky #publichealth #Enterovirus D68 - a respiratory 🦠 that causes severe respiratory infections in children but can, on occasion, enter CNS) & cause a debilitating paralysis such as acute flaccid myelitis .

Enteroviruses use two start sites to gain an edge 🦠🧬 #Enterovirus

Check out the latest @reviewcommons.org #preprintpeerreview of this study Lulla @valerialulla.bsky.social ‪ @cam.ac.uk

Reviews and author's reply here 👇
doi.org/10.1101/2025...

Taiwan reports severe enterovirus infections among newborns | Taiwan News | Jun. 17, 2025 19:43 CDC warns of peak infection period through July as 2 infants die from echo 11 last week | Jun. 17, 2025 19:43

Severe #enterovirus #infections among #newborns reported in #Taiwan ...

| #Asia | #babies | #infants | #virus | #echovirus | Via taiwannews .com .tw

Thread by @microbeminded2 on Thread Reader App – Thread Reader App @microbeminded2: If you are a patient that meets #ME/CFS and #PEM criteria, info on the specific #infections or exposures that led to onset or exacerbation of your symptoms is of major importance. That info will hel...…

threadreaderapp.com/...

This thread by Amy Proal is densely packed with insight.

#MEcfs #Enterovirus #Virology #LongCOVID #Neuroinflammation #OffLabel #PrecisionMedicine
1/3

Gaps in surveillance leave European children at risk of acute flaccid myelitis www.news-medical.net/news/2025060... #AcuteFlaccidMyelitis #AFM #paralysis #childhealth #Europe #enterovirus #publichealth #neurology #infectiousdisease @eurosurveillance.org

Triple Drug Combo May Halt Enterovirus Infections All three components have previously completed clinical trials for other applications and established safety profiles in humans.

A multinational research team has developed a 3-drug combination that may inhibit #enterovirus replication in human cell and organoid culture, with the potential for treating enterovirus-triggered type 1 #diabetes. 🧪

Read more in this piece by @conexiant.bsky.social
conexiant.com/family-medic...

For the 1st part of the afternoon
@dukemedschool.bsky.social #SpatialBiology talks #CarolynCoyne of #DukeMolecularGenetics & #Microbiology spoke on #enterovirus in #T1D, #JingXu of #DukeAnesthesiology on #SpatialTranscriptomics in #hDRG, and #ZachReitman of #DukeRadiology on #MidlineGlioma 🧬🥼💻🧠🐀🧪🧫

#Enterovirus D68 can lead to severe respiratory illness in even healthy kids

Hospitalized children who have an underlying condition other than asthma or who have reactive airway disease are at higher risk for poor outcomes.

www.cidrap.umn.edu/e...

Return of the Biennial #Circulation of #Enterovirus D68 in #Colorado #Children in 2024 Following the Large 2022 #Outbreak

Return of the Biennial #Circulation of #Enterovirus D68 in #Colorado #Children in 2024 Following the Large 2022 #Outbreak, etidiohnew.blogspot.com/2025/05/retu...

Coxsackievirus A24: A Causative Agent of Acute Haemorrhagic Conjunctivitis Outbreak in Dar es Salaam, Tanzania, between January and February 2024 Background On 15 January 2024, the Ministry of Health (MOH) reported a notable outbreak of acute viral conjunctivitis in the city of Dar es Salaam. In this study we investigated the causative agent of...

Finally out: www.medrxiv.org/content/10.1... - work by myself together with great colleagues from Tanzania's National Public Health Lab & elsewhere on the outbreak of Coxsackievirus A24-caused Acute Haemorrhagic Conjunctivitis in Dar es Salaam last year #enterovirus #publichealth Also see this

CHP investigates severe paediatric case of COVID-19 co-infected with rhinovirus/ enterovirus The Centre for Health Protection (CHP) of the Department of Health today (April 30) received a report of a case of severe paediatric COVID-19 and rhinovirus/ enterovirus infection and...

#HK CHP investigates severe #paediatric case of #COVID19 co-infected with #rhinovirus / #enterovirus www.info.gov.hk/gia/general/...

He is still hospitalised at the #PICU of KWH and is in #critical condition.

How concerning is the detection of the polio virus in European cities’ wastewater systems? Dr Muiris Houston: This is a wake-up call for Europe. It means any gaps in vaccination coverage could see a resurgence of the disease

How concerning is the detection of the #polio #virus in European cities’ #wastewater systems? ...

| #Enterovirus | #poliomyelitis | #PublicHealth | #poliovirus | Via @irishtimes.com

New data on the link between #enterovirus infections and type 1 #diabetes, throughout the natural history of #T1D #DiabetesResearch #Endocrinology #MedSky

Joint analysis of nPOD Diabetes issues finds #enterovirus (EV) RNA in pancreas &lymphoid tissues with selected EV-specific methods. #EV RNA in #T1D spleen was frequent with properties previously observed in persistent infections link.springer.com/article/10.1... 🔓

Extensive data on potential links between #enterovirus infection and development of #T1D #DiabetesResearch #nPOD #Islets #MedSky

Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue - Diabetologia Aims/hypothesis Previous pathology studies have associated enterovirus infections with type 1 diabetes by examining the enterovirus capsid protein 1 (VP1) in autopsy pancreases obtained near diabetes ...

Joint analysis of nPOD Diabetes pancreas finds multiple markers of #enterovirus infection associated with type 1 diabetes, supporting efforts to prevent #T1D by vaccination and/or antiviral therapy.
link.springer.com/article/10.1... 🔓

Conference season is back! 🔬🧪

We’re excited to return to Nové Hrady for the XXI Discussions in Structural Molecular Biology by @structbiocssb.bsky.social.

Closing the final session, Pavel Plevka dived into the fascinating world of #enterovirus entry—a great way to wrap up the meeting!