@reviewcommons.org is growing - in ways more than one. Our editorial panel extended to include expert editors of @elife.bsky.social, @genetics-gsa.bsky.social and #G3 to handle #PreprintPeerReview on our behalf. Plus, we have #JournalOfGeneralPhysiology joining our affiliate program 🥳🎉👏

Publishers join the Review Commons peer review process  – Features – EMBO Editors from eLife, Genetics, G3 and Journal of Cell Biology will contribute to the EMBO preprint peer review platform

Big New! @elife.bsky.social @genetics-gsa.bsky.social #G3journal are joining editorial forces with @reviewcommons.org - bringing not just field-specific expertise to the process but also making #PreprintPeerReview a truly collaborative effort!🎉👏

Read more to find out👇
www.embo.org/features/pub...

I’m back in London today and tomorrow at the Future of Scientific Publishing conference at The Royal Society on behalf of @prereview.bsky.social. If you’re also here and want to connect and chat, particularly about #preprintpeerreview, reach out!

🦠Bacterial toxin Cpe1 hijacks topoisomerases inhibiting cell growth💀

Study from the lab of @seeyeunting.bsky.social #AcademiaSinicaTaiwan

#Preprintpeerreview by @reviewcommons.org

Reviews and author's response available here 👇

doi.org/10.1101/2024...

Enteroviruses use two start sites to gain an edge 🦠🧬 #Enterovirus

Check out the latest @reviewcommons.org #preprintpeerreview of this study Lulla @valerialulla.bsky.social ‪ @cam.ac.uk

Reviews and author's reply here 👇
doi.org/10.1101/2025...

CCDC32 helps clathrin-coated pits take the plunge—links to cardio-facio-neuro-developmental syndrome 🫀🔍

🆕study by Yang et al, University of South China and @utdallas.bsky.social

#preprintpeerreview by @reviewcommons.org

Reviews and author's response👇

bioRxiv doi.org/10.1101/2024.06.26.600785

Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell proliferation In response to infection or vaccination, a successful antibody response must enrich high-affinity antigen-reactive B-cells through positive selection, but eliminate auto-reactive B-cells through negat...

B-cell decisions depend on signal timing ⏱🧬🔁
Modeling reveals how BCR & CD40 cues shape immune fate.
#Immunology #Bcells #NFkB

Study from the Hoffman lab @uofcalifornia.bsky.social

🆕 #preprintpeerreview by @reviewcommons.org

Reviews and author's response 👇

doi.org/10.1101/2024...

Decoding kidney fibrosis with time-resolved multi-omics
#KidneyFibrosis #MultiOmics

Tuechler et al 2025, study led by Rainer Pepperkok @embl.org and @juliosaezrod.bsky.social

🆕 #preprintpeerreview by @reviewcommons.org

>> doi.org/10.1101/2024...

TBX1, a T-box transcription factor shapes the fate of cardiopharyngeal mesoderm.

Lanzetta et al. 2025

🆕 @reviewcommons.org #preprintpeerreview @biorxivpreprint.bsky.social

>> doi: doi.org/10.1101/2024...

🧬 Can one enhancer control genes in different TADs at the same time? Turns out—yes.

Williamson et al. 2025, study by @wbickmor.bsky.social @edinburgh-uni.bsky.social

🆕 @reviewcommons.org #preprintpeerreview
@biorxivpreprint.bsky.social

>>doi: doi.org/10.1101/2024...

When it comes to nodal distribution, oligodendrocyte heterogeneity does matter!

Egawa et al. 2025, study by Hiroshi Kuba ‪‪@ en.nagoya-u.ac.jp

🆕 #preprintpeerreview by @reviewcommons.org

>> doi.org/10.1101/2024...

How does kinesin stay in sync while walking? Study shows a role for the neck linker. #Kinesin #CellBiology #MolecularMotors

Niitani et al. 2024, study led by Michio Tomishige from @utokyoofficial.bsky.social

🆕 #preprintpeerreview by @reviewcommons.org

>> doi.org/10.1101/2024...

RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress Genotoxic stress response (GSR) mediated by mRNA translation and decay regulation remains poorly explored. Here, we identify a unique role of yeast RGG-motif protein Scd6 and its human ortholog LSM14A...

RNA-binding proteins Scd6 and LSM14A fine-tune DNA repair under genotoxic stress.

Study led by Rajyaguru #IISC and @stephanwagner.bsky.social

🆕 @reviewcommons.org #preprintpeerreview @biorxivpreprint.bsky.social

>> doi.org/10.1101/2022...

Study mapping the ultrastructural topology of the corynebacterial cell surface.

Study from the Bharat Lab @tbharat-lab.bsky.social
@cellbiol-mrclmb.bsky.social

🆕 Review Commons #preprintpeerreview @biorxivpreprint.bsky.social
>> doi.org/10.1101/2024.09.05.611374

Separase- the chromosome separation enzyme is differently regulated in meiosis.

Study by Christopher Thomas @ovarylab.bsky.social @suzannemadgwick.bsky.social @newcastleuni.bsky.social

🆕 @reviewcommons.org #preprintpeerreview @biorxivpreprint.bsky.social

➡️ doi.org/10.1101/2025...

Study by @kenzoivanovitch.bsky.social @jamesbriscoe.bsky.social @ucl.ac.uk published @embojournal.org featured in @theguardian.com 🎉👏!!!

➡️www.theguardian.com/science/2025/may/13/hear...

#preprintpeerreview @reviewcommons.org
➡️ doi.org/10.1101/2023...

Structure-based mechanism of RyR channel operation by calcium and magnesium ions Ryanodine receptors (RyRs) serve for excitation-contraction coupling in skeletal and cardiac muscle cells in a noticeably different way, not fully understood at the molecular level. We addressed the s...

Structural mapping of ryanodine receptors uncovers distinct Ca²⁺/Mg²⁺ gating pathways.

#IonChannels #RyR #MuscleBiology #Allostery #StructuralBiology

Zahradníková et al #SlovakAcademyofSciences

🆕 #preprintpeerreview @biorxivpreprint.bsky.social

--> doi.org/10.1101/2024...

The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25 Ovarian cancer is the 3rd most common gynaecological malignancy worldwide, with a 5-year survival rate of less than 30% in the presence of metastasis. Metastatic progression is characterised by extens...

Rab25 activates NF-κB to upregulate ADAMTS5, driving ovarian cancer invasion.

Study from @erainerolab.bsky.social @sheffielduni.bsky.social

🆕 #preprintpeerreview @biorxivpreprint.bsky.social

--> doi.org/10.1101/2024...

Interferon function couples immune signaling to the ubiquitin–proteasome system.

Study from the @leunglab.bsky.social @johnshopkinsbmb.bsky.social

🆕 #preprintpeerreview @biorxivpreprint.bsky.social

Referee reports and author's response letter available here

--> doi.org/10.1101/2024...

Modularity of the segmentation clock and morphogenesis Vertebrates have evolved great diversity in the number of segments dividing the trunk body, however the developmental origin of the evolvability of this trait is poorly understood. The number of segme...

Segmentation clock & tissue development are decoupled - explanation for evolution of flexible body plans?
#EvoDevo #SegmentationClock

Study from Verd Lab @bertaverd.bsky.social @oxfordmathematics.bsky.social

🆕 #preprintpeerreview @biorxivpreprint.bsky.social

--> doi: doi.org/10.1101/2024...

Analysis of wild plant pathogen populations reveals a signal of adaptation in genes evolving for survival in agriculture in the beet rust pathogen (Uromyces beticola) Improvements in crop resistance to pathogens can reduce yield losses and address global malnourishment today. Gene-for-gene -type interactions can identify new sources of resistance but genetic resist...

Wild plants serve as reservoirs for crop pathogens-study finds populations and genes linked to resistance evasion.

McMullan et al. 2025 @mcmullan0.bsky.social; lab of @neilhall.bsky.social at @earlhaminst.bsky.social

🆕 #preprintpeerreview @biorxivpreprint.bsky.social

--> doi.org/10.1101/2021...

Rac1 and Nectin3 are essential for PCP-directed axon guidance in the peripheral auditory system Our sense of hearing is critically dependent on the spiral ganglion neurons (SGNs) that connect the sound receptors in the organ of Corti (OC) to the cochlear nuclei of the hindbrain. Type I SGNs inne...

Check out how cell polarity and adhesion guides precise neural wiring in the cochlea, #Neurodevelopment #Cochlea #PCPPathway

Study from the group of Xiaowei Lu @univofvirginia.bsky.social

🆕 #preprintpeerreview @biorxivpreprint.bsky.social

--> doi.org/10.1101/2024...

Early Evidence Base | EMBO

#OpenScience #PreprintPeerReview by @reviewcommons.org
Review 1 doi.org/10.15252/rc....
Review 2 doi.org/10.15252/rc....
Review 3 doi.org/10.15252/rc....

Response doi.org/10.15252/rc....

Early Evidence Base | EMBO

#OpenScience #PreprintPeerReview by @reviewcommons.org
Review 1 doi.org/10.15252/rc....
Review 2 doi.org/10.15252/rc....
Review 3 doi.org/10.15252/rc....

Response doi.org/10.15252/rc....

Early Evidence Base | EMBO

#PreprintPeerReview by @reviewcommons.org
Review 1 doi.org/10.15252/rc....
Review 2 doi.org/10.15252/rc....
Review 3 doi.org/10.15252/rc....
Review 4 doi.org/10.15252/rc....

Author's Response doi.org/10.15252/rc....

Early Evidence Base | EMBO

#PreprintPeerReview by @reviewcommons.org #OpenScience
Review 1 > doi.org/10.15252/rc....
Review 2 > doi.org/10.15252/rc....
Review 3 > doi.org/10.15252/rc....

Response > doi.org/10.15252/rc....

Early Evidence Base | EMBO

#PreprintPeerReview by Review Commons #OpenScience
Review 1 > doi.org/10.15252/rc....
Review 2 > doi.org/10.15252/rc....
Review 3 > doi.org/10.15252/rc....
Response > doi.org/10.15252/rc....

#PreprintPeerReview by @reviewcommons.org #OpenScience
Click the link below for reviewer reports and author's response letter
>eeb.embo.org/doi/10.1101/2024.10.29.620637

Early Evidence Base | EMBO

#PreprintPeerReview by @reviewcommons.org
Review 1 > doi.org/10.15252/rc....
Review 2> doi.org/10.15252/rc....
Review 3> doi.org/10.15252/rc....

Author's response> doi.org/10.15252/rc....

Early Evidence Base | EMBO

#PreprintPeerReview by @reviewcommons.org
Review 1> doi.org/10.15252/rc....
Review 2> doi.org/10.15252/rc....
Review 3> doi.org/10.15252/rc....

Author's response> doi.org/10.15252/rc....