Hey Alice, is there a way for non-US doctors to register?

SC administration of 2g ceftriaxone appears to be well tolerated with favourable PK parameters in non-critically ill patients with severe infections.

Hopeful that this will add to the growing body of literature that normalise the use of SC antibiotics for some patients.

Safety, tolerability, and pharmacokinetics of a 2 g subcutaneous dose of ceftriaxone as an alternative to intravenous delivery | Antimicrobial Agents and Chemotherapy This prospective, self-controlled cross-over design study demonstrates that subcutaneous administration of 2 g ceftriaxone appears safe and well tolerated with a comparable pharmacokinetic profile rel...

Happy to share our latest article in AAC 💊💊

journals.asm.org/doi/10.1128/...

Fantastic article!
Well done @elisemitri.bsky.social and @trubianojason.bsky.social

Logo for the ADVANCE-ID group's 'Bacterial and fungal infections newsletter'.

David Paterson and the ADVANCE-ID team are doing a lot of work for us summarizing recent literature on bacterial & fungal infections & therapies. If you aren't already receiving their bimonthly newsletters, you should! ad-id.co/subscribe

#IDSky #Clinmicro

Our findings support the utility of histopathological analysis whilst also demonstrating a high rate of discordance between histopathology and microbiology.

In contrast to histopathology, positive cultures were not associated with lower rates of treatment success.

Histopathological analysis from proximal bone samples during minor amputations for diabetes-related foot infections: A single-center, retrospective study Minor amputations, defined as resection of bone below the ankle, are important procedures for managing diabetes-related foot infections (DFI). The opt…

Happy to share our latest article that explores the optimal method to determine residual bone infection in DFI.

#IDSky #DiabeticFootInfections #Histopathology

Histopathological analysis from proximal bone samples during minor amp... www.sciencedirect.com/science/arti...

🆕🔥State of art review with many🌟s
+ Prof. Jason Roberts
Antibiotic therapy for severe bacterial infections
🟢When to start and not to start antibiotics?
🟢Mon vs combo Abx
🟢PK/PD principles
🟢Drug–drug inx
A #mustread article for ID professional #idsky
link.springer.com/article/10.1...

Authors conclude: CSF pleocytosis important criterion for encephalitis diagnosis, but 23.7% of those with HSV-1 encephalitis exhibited an absence of pleocytosis on initial LP. Acyclovir initiation should not be delayed in the absence of pleocytosis in patients with suspected encephalitis. #IDSky

Further work is needed to define the optimal screening and management strategies for disseminated cryptococcosis in immunocompromised patients without HIV.

Happy to share our latest publication that highlights various challenges when treating cryptococcal meningitis.

#IDSky
#IDCases
#OpenAccess

doi.org/10.1016/j.id...

Grants being written.
We want to do SNAP but for enterococcus.
Will include amp vs amp+ceftriaxone vs amp+gent comparison for enterococcal endocarditis.
@drtoddlee.bsky.social @gurujosh.bsky.social

Histoplasmosis and blastomycosis: Progress and possibilities Histoplasmosis and blastomycosis are important global fungal infections that primarily start as pulmonary pathogens but can lead to disseminated, fatal disease requiring prolonged antifungal therapy.

📣 Lovely comprehensive new review on #histoplasmosis and #blastomycosis by @mikescolarici.bsky.social & @germatologist.bsky.social

Climate change means these #fungi are growing & spreading.
🙏 to these experts for keeping us up to date!

#IDSky #Clinmicro #MedSky

www.cmi-comms.com/article/S295...

nothing I'd rather wake up at 5am to do than talk to @angelahuttner.bsky.social (while she's vacationing in Greece!) & @steventong.bsky.social @gurujosh.bsky.social in Australia about SNAP Trial results presented at #ECSMIDGlobal

Joint Communicable/Breakpoints episode dropping on May 5th!! #idsky

Excited that at #ESCMIDGlobal 2025, SNAP trial results for PSSA and MSSA silo backbone domains will be presented.

What's more it's a new format 2 hour session! 3 trials (SNAPx2, CLOCEBA), with expert led & audience discussion.

Sat April 12 16:15 - 18:15 Hall 13

Drinks after

@escmid.bsky.social

Check out our latest publication in @ofidjournal.bsky.social led by Usha Manickavasagar.

t.co/COtFoJPYc6

We describe the diverse clinical presentations, attributable mortality rate, and ill-defined treatment of Mycobacterium bovis infections after intra-vesical BCG installation.

This interesting case is a great example of how a common infection can present atypically in an increasingly diverse and complex immunocompromised population.

Happy to share our latest publication #IDsky

Disseminated enterovirus infection treated with intravenous immunoglobulin in a patient on maintenance ocrelizumab for multiple sclerosis casereports.bmj.com/content/18/1...