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Posts by Sam Connell

Video

What if you got to work with some of your best friends on a science project? I can't publish how fun this was, but I can show you the data (🧵)! Last week, we posted our second neutrophil swarming paper to bioRxiv and I wanted to post my favorite videos here~
www.biorxiv.org/content/10.6...

12 hours ago 83 24 2 3

Very cool Chad! Big fan of that objective pair...

8 hours ago 1 0 1 0
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My first post here, we have a new preprint out from @aicjanelia.bsky.social! Upright LSFM is fantastic for live imaging, but not amenable to all samples - especially those requiring an air-liquid interface. We worked with Tokai Hit to try to fix that.

www.biorxiv.org/content/10.6...

17 hours ago 28 12 3 1

So happy to have been part of this! Thanks Chad and team 🪰🪰🪰

8 hours ago 3 2 1 0
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Expansion microscopy Nature Reviews Methods Primers - Expansion microscopy enhances conventional imaging by physically enlarging samples within a hydrogel matrix, surpassing diffraction limits. In this Primer, Vo et...

📷 Expansion microscopy turns 11 — and our comprehensive Primer is now live in
@natrevmethodsprimers.nature.com
! A decade of ExM, 1000+ papers, and still accelerating. Co-authored with the father of the field,
@eboyden3.bsky.social
, + Ha Vo & Rong Xu. 📷 Free to read: rdcu.be/fdQPH

16 hours ago 12 5 0 0

🚨🚨 ALERT 🚨🚨

I finally got Andy McCabe to sign up on Bluesky @therealmccabe.com ! Please follow him here, share this post widely, then check out his first ever Substack article and subscribe there as well (no paywalls!)

11 hours ago 1394 523 108 18
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Junior Specialist- Henderson Lab University of California, Davis is hiring. Apply now!

If you know of a graduating senior who might want to spend a gap year in @jmhenderson.bsky.social's productive, supportive, and fun lab, pass along this ad for a full-time, NIH-funded RA position!

recruit.ucdavis.edu/JPF07601?fbc...

14 hours ago 5 6 0 0
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Mark your calendars 🗓️ & register now!

So excited to share some of our recent science with everyone 🧪👩🏻‍🔬

12 hours ago 4 2 0 0
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Drinking Culture Hi, My name is Georgia Kash and I am an 8th grader at dukeschool in durham which is a project based school, and for my final project I am studying the effect of mocktails on the society. A part of th...

My daughter has a capstone project (for 8th grade) on mocktails and how they have impacted drinking culture. She put together a survey for this project, if you are so inclined to take it, feel free:

docs.google.com/forms/d/e/1F...

12 hours ago 40 21 12 1

Last call for free!

1 day ago 3 3 0 0

All federal wind power R&D at the Department of Energy is $0.137 billion. So the government is paying 7x the amount it spends on all wind power R&D just for a fee to kill one wind project. Seems bad.

1 day ago 956 382 12 6

I am working so incredibly hard with other people to try and stabilize things in science and government while there are vandals tearing it all apart for selfish reasons of profit and ideological beliefs that are incompatible with healthy, safe, and informed society.

I’m exhausted.

Need to sleep.

1 day ago 64 9 6 0
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Ferroptosis induces heterogeneous death profiles that are controlled by lysosome rupture Das et al. show that the death mechanism ferroptosis is regulated in cell populations by the parallel induction of necrotic and apoptotic modes of execution. Death propagation, a unique feature of nec...

Is ferroptosis a form of cell death?
Or is it a process that ends up in apoptosis or in lysosomal cell death?
It depends on who you ask. But we better agree on definitions, because there are clinical implications

I would love your opinion @angelifriedmann.bsky.social

www.cell.com/developmenta...

1 day ago 19 6 1 0
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These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9

1 day ago 176 52 4 4
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For U.S. medical researchers, shrinking labs and bare budgets are the new reality The Trump administration has slashed the number of grants from the National Institutes of Health, with far fewer focused on women, cancer and mental health.

Bhattacharya, Letai & other politicals at NIH keep trying to to say all at NIH is fine, because they spent the full budget last year. This well researched article from @carolynyjohnson.bsky.social explains exactly why many scientists are still struggling. www.washingtonpost.com/science/2026...

1 day ago 115 60 3 2

Have fun y'all!

2 days ago 0 0 0 0

With some extra care and keeping the n on the lower side, the bean liquor could hit some extra amazing levels of outstanding. I do understand why you'd hit this exploration and respect the process. When infinity Ramen broth is rocking, I think it never cools down, hence the food safety protection.

2 days ago 2 0 2 0
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This sounds reasonable when keeping n relatively low, but from a food safety perspective, I'd consider not approaching t=infinity. In the world of food safety, there are some toxins produced that are not killed by heat. I am careful, but not that careful - starting fresh provides some protection.

2 days ago 3 0 1 0

Experimenting with an “infinity bean broth”: save broth from cooking beans and use it to cook the next beans. I’m on the third iteration and am not optimistic about endless n+1 but it’s given me something to do when I don’t use it all. Will anyone in #beansky town warn me from the path to ruination?

2 days ago 4 2 1 0

I'm looking for #NewPIs (<3 years as lab heads) in the gene regulation/functional genomics space. If you are one or know one, please comment below! 🧪

3 days ago 11 25 12 0
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Cell-type-targeted mitochondrial transplantation rescues cell degeneration - Nature MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

Super cool paper - MitoCatch for cell-specific-targeted mitochondrial delivery! www.nature.com/articles/s41...

3 days ago 7 1 0 0
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Microscopy preprints – applications in biology - FocalPlane Microscopy preprints – applications in biology - News

🔬📖Check out our #preprint list showcasing the latest research using microscopy to answer questions in biology.

📨Drop us a message if you have any recommendations for this list.

focalplane.biologists.com/2026/04/17/m...

3 days ago 7 2 0 1

Hello! Does anyone in my network have expertise on Puerto Rico (esp. historical expertise on Puerto Rican culture circa 1959)? My friend is a producer and is putting on a musical about a family in this time period.

Please share in your networks!

3 days ago 3 13 1 1
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Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...

This program transformed my career! Please apply.

@hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits. Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

4 days ago 80 45 0 2
These fuckin chuds

These fuckin chuds

Naming your biology LLM after Rosalind Franklin is… hell is not hot enough

4 days ago 1003 232 29 62
Rage Against the Machine - Evil Empire

Rage Against the Machine - Evil Empire

Tonight's #vinyl selection: #RageAgainstTheMachine #EvilEmpire
30 years ago today, @rageagainst.bsky.social released their 2nd album.
#BullsOnParade #DownRodeo #PeopleOfTheSun #Vietnow #WithoutAFace #YearOfThaBoomerang #RATM #Vinylsky #NowSpinning #VinylCommunity #MusicSky #NEOVC #MusicAlmanac

4 days ago 20 3 0 0

You appoint Hollywood / reality TV show people to important positions and you get Hollywood / reality TV show performances.

4 days ago 9 1 0 0
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Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...

@hhmi-science.bsky.social's
#FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits

Stable, sustained support can transform your career:

Senior Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

4 days ago 94 63 5 1

I just got my new @socdevbio.bsky.social swag! Can’t wait to get the rest of the shirts and represent all the model organisms! Amazing designs by Sarah Paramore! #DevBio 🤩😍

4 days ago 35 5 3 0

Naw...the man had a day off, so was pinch hitting. It was a wild spot in the order, no doubt.

5 days ago 1 0 0 0