I’m looking for an automated way to read others’s scientific data without giving credit or acknowledgement, and also claim full credit for insights from it. And I want it to have a fitting name
OAI: say no more
Also, it's retroactively hurting people who applied before knowing these rule changes, or were already contemplating their future submissions. There must be a better way (and I think letting AI review/triage grants is horrible). E.g., increase the number of panels, or make virtual triage sub-panels
I can certainly sympathize with the plight of the panelists, but this is a wrong decision. The idea of ERC is encouraging high-risk proposals. Saying "if a couple of panelists think its too crazy", you are banned for 2-3 years is the opposite message of discouraging bold ideas
Super excited that our two companion papers on saturation genome editing (SGE) of RNU4-2 and discovery of a novel recessive neurodevelopmental disorder (NDD) were published yesterday 🥳
SGE experiment: www.nature.com/articles/s41...
Recessive NDD characterisation: www.nature.com/articles/s41...
🧵
We are excited to share our new paper in Molecular Cell uncovering how the viral lncRNA RNA2.7 reshapes host cell biology!
sciencedirect.com/science/authShare/S1097276526001565/20260324T143400Z/1?md5=16c84051c2f253c4665427f837a529d3&dgcid=author
A thread 🧵
As a kid, watching Walker, Texas Ranger taught me that many problems in life can be solved by a well-timed roundhouse kick, a lesson that has served me well in academia
Timely reminder that a few years ago we named the Norris1 lncRNA, which remains quite enigmatic, but, fittingly for Chuck, is expressed primarily in the testis pmc.ncbi.nlm.nih.gov/articles/PMC...
Human DHX29 detects nonoptimal codon usage to regulate mRNA stability | @science.org www.science.org/doi/10.1126/...
There has never been a better time to study functional and mechanistic biology at the organismal (!) level than now in the age of AlphaFold and CRISPR.
"This observation supports the error hypothesis and suggests that metazoan transcript diversity is largely deleterious." Love this since it matches my priors :-) dx.plos.org/10.1371/jour...
This line of business would make tons of $$$ in Israel this week
Out today: We discovered new viral proteins that target immune signaling molecules, solely based on their AlphaFold-predicted shapes
www.science.org/doi/10.1126/...
Congrats Nitzan Tal and coauthors! Thank you Kranzusch lab for the fun collaboration!
Linking below previous thread on our findings
Don’t worry. Soon, everyone here will be an expert on air wars in the Middle East.
TFW you generously accepted review invitations thinking you'd have two ~18 hr flights TLV<->Cancun this week for reviewing, then war breaks out, but you still need to review these papers/grants
... and we're back to in-shelter selfies!
Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.
🤩💪 Out now! 3D regulatory hubs in sex determination
With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social
1️⃣ METALoci – explore #3DGenome 🧬
2️⃣ Non-coding region controlling Fgf9 🧩
3️⃣ Meis genes = new key players 🌟
👉 rdcu.be/e5sm2
1/n Bluetorial 👇
Integrative multiomics analysis and CRISPR screening identify functional noncanonical translation loci in the mouse immune system. www.biorxiv.org/content/10.64898/2026.02...
So awesome!
This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...
Tread -1- EpiSci - I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below)
"The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A.
www.biorxiv.org/content/10.6...
Ever notice that when one gene is disrupted, its orthologs get upregulated? This phenomenon, known as transcriptional adaptation, has been controversial and mysterious - glad to see that we are starting to learn how it works.
Ooooh. Cool new paper on origins of life. A simple 45-nucleotide RNA molecule that can perfectly copy itself.
www.science.org/doi/10.1126/...
One on left is a black dog and above it the words “Reality”. Below it is “I chased a squirrel” One the right is a black dog and above it says “LinkedIn”. Below it says, Proud to announce that I effectively executed a rapid-response squirrel displacement strategy to mitigate potential yard intrusions. Humbled by the unwavering support of my family and local stakeholders. This experience reinforced the importance of vigilance, ownership, and continuous improvement. Looking forward to scaling this impact in future engagements.
😂
Nup42 safeguards heat-induced mRNAs from nuclear condensation tosupport chaperone synthesis www.biorxiv.org/content/10.64898/2026.02...
Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...
This time we are back at the bigger Sela auditorium after filling Lopatie center to the brim last time. Israeli RNA/DNA enthusiasts - hope you can join us. RT please!
Save the date! May 4th this year will be both Star Wars Day, and the 3rd installment of our Nucleaic Acid Therapeutics meeting at the Weizmann Institute. As in 2023 and 2025, we aim for an audience of ~300 researchers interested in RNA and DNA therapies, ~50/50% academy and industry.
Tweet exchange in which a photo of Anne Hathaway is posted by @TheRoyalSerf, to which user @VvSchweetz24 replies "@grok...do your thing. @Grok replies: Anne Hathaway isn't Jewish; she was raised Catholic but left the church. She married Adam Shulman (who is Jewish) in 2012 and celebrates Jewish holidays with their kids. SHe's played Jewish roles, like in "Armageddon Time."
pretty sure he meant the other thing, grok, but very cool that those are your two things
