Snapshot of a model showing two chromosomes (red spheres on the left and yellow ones on the right) before they are fully separated. Kymographs (bottom row) show the density of two daughter chromosomes (left) and ribosomes (right) as a function of time in the presence of nonequilibrium reactions of ribosomes. Blue corresponds to low and red to high density. As time progresses, the two chromosomes separate, but only when the reactions are present. The snapshot above corresponds to time t = 0 in the kymographs.

📢Our MD simulation is out in Biophysical Journal!

The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.

authors.elsevier.com/a/1mBGt_9FM7...

#Microbiology #Biophysics

Diagram of an E. coli cell showing polysomes pushing sister chromosomes apart. Bottom heatmaps show cell-cycle-dependent changes in DNA and ribosome density distributions, and constriction formation. The top right corner shows normalized mid cell amounts from these heatmaps (integrated between the dashed horizontal lines).

Our latest work is out in PNAS!🎉
We show that nonequilibrium polysome dynamics help drive sister chromosomes apart. The closing division septum also contributes via steric interactions.👇
www.pnas.org/doi/10.1073/...

#MicroSky #Microbiology #Biophysics #CellBiology

Opinion: How much are MPs entitled to know about research grants? Not as much as they think A parliamentary committee is asking for academics’ private information on a strange anti-DEI crusade

How much are MPs entitled to know about research grants? Not as much as they think. A parliamentary committee is asking for researchers' personal information in what seems like an anti-DEI crusade, by @picardonhealth.bsky.social www.theglobeandmail.com/opinion/arti... via @theglobeandmail.com

BiSP - MicrHub Fourwaves - BiSP - MicrHub

Plus que 10 jours avant la fin des soumissions des résumés pour le BiSP qui aura lieu le 5-6 novembre 2025 à l'Université de Sherbrooke. Nous aurons aussi la chance de recevoir @lalouxlab.bsky.social et @bjesseshapiro.bsky.social

Partagez! @micrhub.bsky.social

event.fourwaves.com/bispmicrhubs...

Thank you, Seamus! Glad you find it useful.

Microfossils: Mimicking early life-forms in the lab

Studying the growth of bacteria without cell walls in an artificial environment can shed new light on the proliferation of primitive life-forms billions of years ago.
buff.ly/W7xDrWV

Saddened to learn of the passing of Moselio "Elio" Schaechter—Distinguished Professor at Tufts, SDSU and UCSD—humanist and visionary leader in the fields of microbiology and scientific communication—mentor, friend, and inspiration to me and so many others

Small Things Considered
Big Things Achieved

Please repost: PhD position with my lab and @weisslab.bsky.social in a great collaboration on bacterial adhesion #microsky. See drive.google.com/file/d/1GJD4...

Congratulations, David!

How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print @natcomms.nature.com. Nice work by @mariedelaby.bsky.social, Liu Yang et al. See original 🧵, different colours, same data and conclusions.

Assistant Professor (Research), Department of Microbiology & Immunology, (C2-240724) Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...

Come join us at @mcgill.ca as an assistant professor in virus-host interactions! Please share widely.

mcgill.wd3.myworkdayjobs.com/en-US/McGill...

🚨👉 Please check our recent work on bacterial cell division. In situ Cryo-ET reveals the cellular function of the penicillin binding protein 1b supported by AFM, live-cell imaging, in silico AlphaFold proteome screen and TIRFM. Hope you enjoy the read! #teamtomo #cryo-ET ❄️🔬🐎 big thanks to the team!

The modified announcements say that up to 15% of doctoral, and 20% of postdoctoral, awards can be held by international scholars.

Wahlrecht für Deutsche im Ausland sichern: Keine Stimme darf verloren gehen! - Online-Petition Alle deutschen Staatsangehörige sollten ihr Wahlrecht ausüben können! Jetzt handeln! Problem: Viele deutsche Staatsangehörige im Ausland können ihr Grundrecht auf Teilnahme an der Bundestagswahl fakti...

#Bundestagswahl Participating in elections is more important than ever, but for the 3-4Mio Germans abroad voting is way too complicated and this time not possible for many. Please sign this petition and share: www.openpetition.de/petition/onl...

Please repost!!!!!
Abstraction submission for the next Great Wall Symposium is now open!
Come to Sicily in September and learn the latest on bacterial cell wall biology.
thegreatwall-symposium.org/abstract-sub...

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...

These mouth bacteria use a new type of cell division to make 14 cells at once The newfound strategy seen in C. matruchotii might help oral bacteria recover lost territory after each eviction by toothbrushing.

Crazy stuff in PNAS

dental plaque bacterium 𝘊𝘰𝘳𝘺𝘯𝘦𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘮𝘢𝘵𝘳𝘶𝘤𝘩𝘰𝘵𝘪𝘪 can divide into an unprecedented 14 daughter cells at once—then each daughter cell starts growing immediately in a rare process called multiple fission, achieving 0.5 mm per day of expansion

www.snexplores.org/article/bact...

We’re looking to hire a theoretical #biological #physicist at either the Assistant or Associate professor level. The post closes soon, so please spread the word. #Toronto is a great place to live and work.

jobs.utoronto.ca/job/Toronto-...

jobs.utoronto.ca/job/Toronto-...

Cinq à Science (@cinqascience.bsky.social) On se retrouve autour d’un verre, on écoute une présentation, puis on échange de manière informelle. Lien: https://tinyurl.com/4t7nvz6y

Excited to share our Cinqascience.bsky.social and our sites.google.com/view/cinq-a-... where you’ll find all details about our activities in Montréal and Québec! A huge thank you to Mafar (from @svanteeffelen.bsky.social sky.social lab) for supporting our communication 💙 #CinqAScience #5AScience

Thanks!

Thanks for putting this together. Could you add me?

Could I join as well? Thanks!

The Escherichia coli replication initiator DnaA is titrated on the chromosome DNA replication initiation is orchestrated in many prokaryotes by the replication initiator DnaA. Two models for regulation of DnaA activity in Escherichia coli have been proposed: the switch between ...

New preprint spear headed by the amazing #LorenzoOlivi: "The Escherichia coli replication initiator DnaA is titrated on the chromosome" using, among many other techniques, #sptPALM to determine growth dependent mobilities of DnaA diffusing in live cells. doi.org/10.1101/2024.10.07.617004 1/n

Montréal, mark your calendars! Manon, postdoc in my lab, will lead the next Cinq à Science on 11/27, tackling the critical topic of antibiotic resistance (public, in french). Let’s show up big for Manon and cheer her on as she takes the stage! 🚀🔥 #SupportScience #AntibioticResistance #MontrealEvents

2 days left. Asst/Assoc Prof position in bacteriology, Université de Montréal. Deadline ***Nov. 15*** come join our growing community of bacteriologists. BTW Canada is the USA’s Bluesky!

Assistant or Associate Professor in Bacteriology - Montréal, Quebec (CA) job with University of Montreal | 664282 Université de Montréal (UdeM) is looking for an Assistant or Associate full-time professor in the field of bacteriology.

Please repost: Nov. 15 deadline! We are building a strong bacteriology community at Univ de Montréal, including recent hires Sven van Teeffelen, Frédérique Le Roux & myself. Moving to Montréal in 2018 is one of the best career decisions I made. Come join us! jobs.sciencecareers.org/job/664282/a...

Assistant or Associate Professor in Bacteriology - Montréal, Quebec (CA) job with University of Montreal | 664282 Université de Montréal (UdeM) is looking for an Assistant or Associate full-time professor in the field of bacteriology.

#JobAlert for (Asst/Assoc) Professor in #bacteriology in our Department of Microbiology at the @UMontreal. Join our increasing group of bacteriologists including recent hires of
@brunlabcaulo.bsky.social, Frederique Le Roux and myself. jobs.sciencecareers.org/job/664282/a...

Very happy that our review on #singleparticletracking #SPT from experiment to analysis is now published. With
@weisslab.bsky.social and Francois Simon. Must read for anyone tracking fluorescent molecules transitioning between motion states. rdcu.be/dTKHd vanteeffelenlab.org/publications