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Posts by Otto Balsiger

STRAVINSKY study: update on findings | British Society for Immunology STRAVINSKY study: update on findings | British Society for Immunology

📣 Join us for a free public webinar on 30 April, 18:00–19:00 BST!

Hear the latest updates from the STRAVINSKY study, exploring COVID 19 risk in people with weakened immune systems. It’s free to attend with an open Q&A

Register now: vist.ly/4yunx

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Out of the shed and into the field: an immune toolkit for measuring wild ungulate immune phenotypes at multiple scales Here we demonstrate the utility of our field-tested “immune toolkit” in describing the immune phenotypic heterogeneity of bighorn sheep (Ovis Canadensis) a

Measuring immune function in the wild is key to understanding resilience and disease. New open‑access research presents a practical immune toolkit for wild ungulates, revealing variation across individuals, populations and landscapes in bighorn sheep.

vist.ly/4z6gk

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Neuraminidase A controls pneumococcal recognition and fate: deficiency enhances immune sensing and intracellular survival, while treatment promotes phagocytic clearance. Abstract. Streptococcus pneumoniae (pneumococcus) is a leading cause of bacterial meningitis worldwide and is associated with cerebrovascular complications

How Streptococcus pneumoniae interacts with innate immunity matters. New open‑access research shows neuraminidase A (NanA) shapes immune sensing and phagocytic clearance in microglia and macrophages, with implications for pneumococcal meningitis.

vist.ly/4y22j

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Sounds like a great meeting

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Treg therapies could restore immune tolerance, but key barriers remain. #ImmuneTherapies26

This session explores challenges including specificity and cell trafficking and how next generation approaches aim to overcome them.

Register now: vist.ly/4ynds

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Vaccines protect against some of the most serious diseases we know. But their impact goes beyond infection.

Research suggests they may also support long-term health, including reducing cardiovascular risk.

Explore our latest #CelebrateVaccines blog! ➡️ vist.ly/4yngv

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📢 Call for submissions: Cancer Vaccines – Global Advances

We invite research, reviews, clinical studies, commentaries & TrialsWatch articles on personalised and off‑the‑shelf cancer vaccines.

Submit by the end of April 2026

#callforpapers

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📢 Calling all translational and clinical immunology researchers! We welcome high‑quality studies with the potential to transform understanding of human disease or change clinical practice.

Learn more about submitting: vist.ly/4ymyd

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Inborn errors of immunity-related immunological mechanisms and pharmacological therapy alternatives in periodontitis This article discusses the essential function of neutrophils in preserving periodontal health and how the deficiency in these immune cells can lead to seve

Severe periodontitis reflects complex immune–microbiota interactions, especially in patients with immune dysregulation. This open‑access review explores how immunology‑informed, targeted therapies could complement conventional dental treatment.

vist.ly/4yh95

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Last chance to register for #UKimmunomet26!

Join us in Newcastle next week for two days of immunometabolism research, with leading speakers & dedicated Bright Sparks sessions showcasing ECRs.

📍 Hilton Newcastle Gateshead
📅 16–17 April

Register here: vist.ly/4xvny

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💉 Did you take part in our #CelebrateVaccines campaign? If you’re passionate about public engagement and immunology, consider applying for Public Engagement Secretary.

UK‑based | 4‑year term | BSI members

⏰ Nominations close Thursday 16 April

vist.ly/4ycuw

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Clinical and experimental treatment of advanced melanoma with a focus on immunotherapy Immunotherapy has revolutionised outcomes for patients with advanced melanoma. Here we review the immunobiology of melanoma, current standard-of-care treat

Open‑access review shows how immunotherapy has transformed advanced melanoma treatment, with many patients now likely cured, and highlights emerging options for those who don’t respond to current therapies.

vist.ly/4yczq

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Open‑access review explores how targeting monocyte dynamics could offer new therapeutic approaches for multiple sclerosis, with insights from experimental models highlighting monocyte plasticity and inflammation resolution.

vist.ly/4ydua

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New open‑access paper outlines how the UK Vaccine Innovation Pathway is accelerating cancer vaccine trials across the NHS, boosting recruitment, streamlining delivery, and supporting equitable access.

vist.ly/4x25i

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Most flow cytometry problems start before you even press “run”.

Our course on 11 & 18 May with Derek Davies focuses on panel design, real immunology examples & fixing issues you’re actually facing.

Feel free to BYOD (bring your own data)! Fully online + 30% off for BSI members.

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Our new blog explores how vaccination programmes evolve, focusing on the introduction of the MMRV vaccine #CelebrateVaccines

In 1988, combining 3 vaccines into 1 helped drive UK uptake above 90%. Now, MMRV builds on this progress...

Read more 👉 vist.ly/4xr7h

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⏰ One week to go!

Nominations for the 2026 BSI committees close 16 April, 12:00 GMT.

Get involved and help shape the future of immunology.

Learn more: vist.ly/4xund

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Neutrophil extracellular traps in rheumatoid arthritis: biomarkers, drivers, and emerging therapeutic targets Neutrophil extracellular traps (NETs) play an important role in the development of rheumatoid arthritis (RA). Clinical evidence shows that components of NE

Neutrophil extracellular traps (NETs) are emerging as both biomarkers and drivers of rheumatoid arthritis, linked to disease activity, treatment response and key pathogenic pathways. Targeting NET formation could open new therapeutic avenues in RA.

vist.ly/4xrct

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Developing immune therapies for rare diseases: big challenges, but real opportunity! #ImmuneTherapies26

From trial design to reimbursement, this parallel session explores how to bring new treatments to smaller patient populations.

Register today: vist.ly/4xpjw

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1 week left to submit your abstract for our immunosenescence meeting! ⌛

Join experts at this event in Guildford on immune ageing, from mechanisms to next generation technologies #ImmuneAgeing26

Submit now and share your work, ECRs especially encouraged: vist.ly/4xp8q

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Want to understand how vaccines actually work? #WorldHealthDay #StandWithScience 🔬

Our guides explain how vaccines work with the immune system to help prevent disease, supporting informed, confident decisions.

Click here to explore our guides: vist.ly/4xjxt

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Is AI more hype than hope in drug development? #ImmuneTherapies26

At the BSI ITS taking place in May, this workshop will explore the practical challenges of applying AI and where it is already making a real impact.

Register now by clicking here: vist.ly/4wxfn

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IFNγ from activated CD4⁺ T cells plays a key role in driving lupus by promoting B‑cell differentiation and autoantibody production. Mice lacking IFNγ showed reduced symptoms, highlighting these cells as a potential therapeutic target.

vist.ly/4wxes

#Immunology #SLE #LupusResearch

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Wild mice show large, robust T‑cell receptor repertoires that stay broad across age and sex, while older mice develop more dominant clones, likely from lifelong pathogen exposure. A fascinating look at how immunity adapts in natural environments.

vist.ly/4wxid

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New research shows that adding CD28 signalling motifs to the CD3ζ chain boosts IL‑2 production and expansion of TCR‑engineered T cells, without reducing cytotoxicity. A promising step toward stronger TCR therapies for solid tumours.

Read here: vist.ly/4wxea

#Immunotherapy #TCells

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How does the environment influence immunity? 🌍

Join us on 11 Sept in London for an event with @london-immuno.bsky.social to explore how microbes, diet, pollution & stress affect immune responses in health & disease #LIG26

Register early for a discount! vist.ly/4w2je

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Did you know there are over 140 autoimmune diseases?

This #AutoimmuneAwarenessMonth, we’re helping spread the word and bring support to those affected, and those researching for cures.

For more info, visit autoimmune.org

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This is going to be a great meeting, wish I was going to be there.

Some of my amazing BSI colleagues will be there so reach out and say hi

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New study shows the Systemic Immune‑Inflammation Index (SIII) is linked to survival in patients on immune checkpoint inhibitors, with lower SIII predicting better outcomes.

Read here: vist.ly/4wedi

#Immunotherapy #CancerResearch

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