Proportions of patients achieving ASAS20 response at the scheduled visits. (A) Proportions of patients achieving ASAS20, ASAS40, and ASAS5/6 responses at week 12, using non-responder imputation (NRI). Additionally, for the primary endpoint, patients who discontinued treatment early due to non–COVID-19 reasons or increased their background medication prior to the week 12 assessment were also analyzed using NRI.

Proportions of patients achieving ASAS20 responses over 24 weeks (observed case analysis)

Phase II/III trial assessed ivarmacitinib (JAK1 inhibitor) for active ankylosing spondylitis. Ivarmacitinib 4 mg showed improved ASAS20 response at wk 12 vs placebo, with efficacy sustained through 24 wks. Infection-related AEs were similar b/w groups

A&R
doi.org/10.1002/art....

#Medsky #Rheumsky

About time we get rid of PBM. They are the bane of the American health system.

Assad's time is up!

US job growth surged in November, adding 227,000 jobs | CNN Business Job growth surged in November, an expected rebound after hurricanes and striking workers heavily distorted the October data.

JUST IN: Job growth surged in November as the US economy recovered from hurricanes and strikes to add 227,000 positions

Lily beats Novo head-to-head
#MedSky

I tuned out of the US based media after the election and now listen to Sky News. It is a breath of fresh air. I have been delivered from the US media that is full of hypocrisy. The US media has an agenda and they will make sure they push it to the max. I am done with it.

New approach to fertility preservation offers young cancer patients hope for biological children later in life More than 200 babies have been born around the world after reimplanted ovarian tissue restored adult women’s ability to conceive a child

New approach to fertility preservation offers young cancer patients hope for biological children later in life: More than 200 babies have been born around the world after reimplanted ovarian tissue restored adult women’s ability to conceive a child

Elritercept is a modified ligand trap that targets activin A and B proteins, which are thought to play a key role in anemia-related diseases. It works by limiting cell signals that cause low blood cell production, which can help increase red blood cell and platelet counts

Hematological emergencies developed after Skysona gene therapy treatment.

Now we are talking. What is good for the goose is also good for the gander. Let the firestorm begin.

Just finished watching the Brighton vs Southampton match. Brighton moves up to the second position ahead of Man City. The Southampton coach should watch it because his aggressiveness will eventually overshadow his team's great skills.

The Democrats need to forget all these name calling and scape goating. It is good to do a postmortem, but put the defeat behind you and chat a new way forward. Midterm election is here.

I was pleasantly surprised to see a pornographic like image today on bluesky. Please increase moderation and root out these bots.

Thread is just an extension of Instagram. Just a waste.

I am officially welcoming myself to Bluesky. I shall be posting engaging stuff that covers a variety of areas such as medicine, genetics, omics, and sports. Please follow to engage constructively.

I still have a feeling they will come back from these 5 defeats. Having said this, they need to start rebuilding. Midfield without Kevin is in shambles. The defence is nowhere to be found today. Sadly, nothing lasts forever.

It will be gradual, but we will get there.

It is pathetic. I would be interested in the thinking of the referee about the issuance of that yellow card.

So it is now a crime to celebrate scoring a good goal 😀