Max Planck Center for Physics and Medicine building
Max Planck Instittute for the Science of Light building
π¨New Lab Alert!π¨ Superhappy to announce that I will start my lab combining photonics & neuroscience at the Max Planck Center for Physics & Medicine in Erlangen & @mpi-scienceoflight.bsky.social in January 2027! Reach out if you're interested in internships, BSc, MSc & PhD & postdoc projects!
It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +π§ͺ
The 35th Ig Nobel Prize ceremony held in Boston in September 2025 will be the last in the United Statesβat least for now.
This year, the beloved spoof on science Nobel Prizes will take place in ZΓΌrich, kicking off a potentially permanent change to European-hosted ceremonies. https://scim.ag/4siO2lS
SeeDB-Live is a tissue-clearing approach for live tissue slices or brains, improving image quality while having minimal effects on electrophysiological properties of neurons. @imailab.bsky.social
www.nature.com/articles/s41...
How do fish localize sound without interaural cues? @johve.bsky.social et al. found a behavioral algorithm for directional hearing that predicts behavior from a pressure/motion phase comparison and accounts for how this relationship varies with distance. www.cell.com/current-biol...
Myself and @immunoah.bsky.social are looking to hire a postdoctoral scientist to build a next-generation high-throughput high-resolution light sheet microscope for imaging entire cleared organs/tissues and to further develop live & fixed tissue clearing methods.
www.nature.com/naturecareer...
Our London-based imaging facility is currently looking for a research software engineer to help develop analysis pipelines for spatial omics. Job advert accessible via our homepage: swcmicroscopy.com Our Neuroinformatics facility also hiring for related roles: neuroinformatics.dev
Wow
Tiny, transparent, and now charted! Our brain atlas of adult Danionella cerebrum includes >200 annotated regions, 29 whole-brain in situs, and male/female reference volumes β openly available, versioned and extendable. Work by @nkadobyansky.bsky.social and team.
www.biorxiv.org/content/10.6...
Thanks to AI, the comprehensive #mesoSPIM-control documentation is finally here π
mesospim.github.io/mesoSPIM-con...
Totally. I feel I can do meaningful things again working on the code 1-2h a week in a fragmented schedule. Its like having an actual software team member (or two).
A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.
Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx
Part of sfb1690.uni-goettingen.de to study hearing, vision, and more.
Plus, you can create pretty pictures as the one below :).
This glass wafer could back up your phoneβand last 10,000 years
Writers for the Superman, Star Trek, and Mission Impossible franchises all dreamed up the idea of storing libraries of data in glass.
Now, Microsoft researchers say they are bringing this vision closer to reality. Learn more: https://scim.ag/4cZ9aJd
Indeed! I managed to generate a decent online documentation for our #mesoSPIM project in 2h, something I was procrastinating for 5 years. Feels like magic.
I have mixed feelings about the music choice, but the tutorial is NICE! Thank you!
If your imaging system has poorly characterized constant distortions leading to chromatic aberration, shoddy stitching, or false measurements (the answer is likely yes), you may want to give this tool a try. Native installers for Linux, Mac, Win under Releases github.com/saalfeldlab/...
I used this one for sealing coverslips in contact with argessive medium (BABB), worked well for me.
Silicon sealant, the type used eg for aquariums, is extremely stable, should work for this application.
Tip: never use superglue anywhere near optics. It slowly outgasses and makes optical surfaces around it hazy. For coverslips one can use nail polish, Picodent dental glue, or silicon from hardware store.
In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...
We have two funded postdoctoral positions available. Topics encompass:
-Next gen light-sheet fluorescence microscopy instrumentation
-Structured illumination microscopy and other approaches to extend the resolution limit.
-Nonlinear microscopy combined with adaptive optics / phase conjugation
Agreed. Strategic quitting is a power move that can open new opportunities. But it must be strategic, not because one is simply tired and needs a vacation.
Has napari helped your research this year? Why not say thank you to free and open source software by making a small donation? Every bit helps your friendly core team fix bugs and bring new features to life! CZI will match up to $75K in donations! opencollective.com/napari/donate
Happy to hear that!
Nice work, bravo!
Finally, the first public release of #BigVolumeBrowser, so after teasers, you can try it yourself. For details, please check the announcement post (1/2)
forum.image.sc/t/bigvolumeb...
Your talk knocked everyone out! Everyone was speechless and could only say "wow, didn't expect that" πThank you for joining us!
The 10 Years of #mesoSPIM Symposium was a blast! ππThe excitement was palpable, and we were all inspired. Three days flew by fast! Thanks to all the attendees, speakers, organizing team, and our sponsors for making it such a memorable event! Let's shape the next 10y of microscopy together! πͺβ€οΈπ¬
This is insane. 13 years ago we bought a million dollar #microscope to do this type of super-resolution imaging. Today, all you need is a smartphone and a few hundred bucks of off-the-shelf components π€―
www.nature.com/articles/s41...
Job opportunity at the University of Zurich! π’
We are looking for a ππππ¨π«πππ¨π«π² ππππ‘π§π’ππ’ππ§ / πππ¬πππ«ππ‘ ππ¬π¬π’π¬πππ§π (ππ%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
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