Dear #RNA sky,
I have a question:
For your custom #RNA synthesis sequences (30nt, non modified +HPLC) destined to be used for in-vitro binding assays, which is your go to company?
Price-quality
😅😅😅😅
Harto de solicitudes de evaluación de proyectos en convocatorias de millones y millones de euros que no reservan una pequeña cantidad para remunerar, aunque sea mínimamente, el esfuerzo, dedicación y conocimiento de los investigadores a los que solicitan su trabajo de evaluación
Yo terminé metiendo la madera en agua hirviendo y comprando muchos bichos come algas... además de tratamientos varios, claro.
Queridas almas diversas, si conocéis a alguien que se vaya a presentar al examen de acceso a FP Grado medio en Madrid, el gran @javierfpanadero.bsky.social ha preparado unos apuntes maravillosos para prepararse la parte de digitalización
lacienciaparatodos.wordpress.com/2026/03/29/a...
Sarepta Therapeutics shares early clinical results showing its investigational myotonicDystrophy type 1 (DM1) therapy (SRP-1003) successfully reaches muscle tissue. 💚🔬These findings highlight a promising approach to effective drug delivery to muscle. investorrelations.sarepta.com/news-release...
Una serie que solo tú recuerdas
La nueva temporada de Catástrofe Ultravioleta está al caer!!
Muy pronto anunciaremos la fecha de salida
Avisa por si tenemos que pedir tb...
Yo, cuando vi baronesa en las opciones, pensé si la compra la haría ella misma o su mayordomo, eso sí, pidiendo los puntos...
¿Loyalty card de Tesco?
New #MolTherapy paper: Delpacibart Etedesiran Improves the Molecular Pathology of Myotonic Dystrophy Type 1 in the Phase 1/2 MARINA® Study. #Myoblue tinyurl.com/3kbu3ty3
NEW: for @nytimes.com, I wrote about a new study showing that queen bumblebees can breathe underwater, surviving submerged for a week
the “remarkable” study stems from a lab snafu, when a co-author thought she accidentally drowned several bees—but later found that they were alive 🧪
gift link 🎁
🗨️ @gmarfanyn.bsky.social: "Es una herramienta terapéutica biológica de mucha precisión que no se había utilizado todavía y que ofrece muchas posibilidades para tratar enfermedades en las que se requiera silenciar un gen o una determinada vía de señalización" sciencemediacentre.es/utilizan-el-...
🧬Utilizan el ‘transcriptoma oscuro’ para reducir la inflamación en ratones y células humanas
🗨️Mª Esperanza Cerdán: "La posibilidad de su uso terapéutico abre un campo interesantísimo de estudio con múltiples aplicaciones"
sciencemediacentre.es/utilizan-el-...
Este viernes, sí este viernes ya, celebramos las matemáticas junto a la @katedra.eus y BCAM con la 7ª edición del Naukas día de Pi en BILBAO
Por la mañana talleres matemáticos para estudiantes y por la tarde, a partir de las 18:30, en el Bizkaia Aretoa, tendremos charlas
naukas.com/2026/02/18/y...
#apaperaday @keystonesymposia.bsky.social special! Klaus & I made it to Banff for the nucleic acid therapy delivery conference. Today’s pick is from Nucleic Acid Therapeutics (NAT) by Andersson et al: an update on assessing hybridization dependent off target risks for NATs. doi 10.1089/nat.2024.0072
Un año esperando para firmar un contrato FPU ya concedido: "Te sientes un poco estafado"
Sí la Administración convocante de unas ayudas no puede supervisar el cumplimiento de las condiciones, ¿para qué está?
www.eldiario.es/1_c710be
A view of the stairs inside Hintze Hall. The handrail is highly decorated, with carvings of animals. At the top of the stairs, a giant sequoia slice is visible.
A view of the ornate arches in Hintze Hall, carved with floral patterns. In the background, stairs are visible.
A view of the ornate arches in Hintze Hall, carved with floral patterns. In the background, there are tall, arched windows, and a statute of Charles Darwin.
Come for the dinosaurs, stay for the architecture! 🤩
We couldn’t resist sharing some more photos taken on a recent stroll around the Museum!
Have you ever noticed these details? ✨
A reminder that humans in cars - notably omitted from this thanks to motonormativity - kill 1.2m people every year
#apaperaday Today's pick is from BMC Neurology by Strober et al on an analysis of caregiver burden for Duchenne muscular dystrophy in 3 different regions (USA, Europe and Japan). Usually these studies focus on only one country. doi: 10.1186/s12883-025-04531-8
Thank you for choosing our figure to illustrate the post! The author is not just a great researcher, but a #raredisease patient herself.
🥰
🧬 New Special Issue of JND out today to celebrate #RareDiseaseDay:
“RNA Therapeutics in Neuromuscular Disorders”
Exploring RNA-targeted approaches in Duchenne muscular dystrophy, Spinal muscular atrophy, Myotonic dystrophy and more: buff.ly/JOtdEJb
#Neuromuscular #RNAtherapeutics #DMD #SMA #DM1
#PLoSBiology Biomedical and life science articles by female researchers spend longer under review journals.plos.org/plosbiology/... "In the PubMed database (>36.5 million articles) the median amount of time spent under review is 7.4%–14.6% longer for female-authored articles."
In a new @wonkhe.bsky.social piece, RoRI fellows Anna Butters and @tomstafford.mastodon.online.ap.brid.gy explore distributed peer review - and what it can (and can’t) fix: wonkhe.com/blogs/a-new-...
Ey... que ya tenemos en marcha dos eventos!!
Bilbao el día de Pi (viernes 13 marzo) y Barcelona «Ciencia para salvar el mundo» (sábado 30 de mayo).
Si estás cerca o conoces a alguien a quien le interese, échanos una mano divulgando las fechas y programas 👇
You are right, we will have to do better next year.
#apaperaday with some delay due to train issues this morning. The pick is from @worldmusclesociety.org journal Neuromuscular Disorders, by Ulm Seiwert et al on 3 cases with duplications of dystrophin exons, only one of which associated with dystrophinopathy. DOI: 10.1016/j.nmd.2026.106335
Not all dystrophin duplications will be pathogenic and the analysis tools used generally will not be able to assess where the duplication is located (in tandem or not). Long read sequencing is expensive, but it can provide clarity.
A computer screen shows the RareDiseaseDay web page. In front of it, aa pile of pink, blue, purple and green balloons, glowsticks and paint jars.
When you are a #raredisease researcher and you search your drawers for ideas of what to do this year...
Finger paint? Balloons? Glowsticks? Party poppers?
A week to go...
#RareDiseaseDay #Shareyourcolours #Showyourstripes
