AACR2026 reports 12 new drugs: degraders targeting HIF-1β, HBS1L, ALK and BRD9; T cell engagers against STEAP2 and Vβ6; biologics modulating EGFR and B7-H3; a CDK2 inhibitor; ADCs for CD30 and ENPP3; and a cyclin interaction inhibitor for solid and hematologic tumors in early clinical trials.
The smiley face phone holder has always been a hit for us!
The quest for the best free merch begins! #AACR2026
@promegacorporation.bsky.social has always been a good place to start!
Once more unto the breach my friend #AACR2026
We used our new ivRIC method to map host proteins inside HIV-1 particles, finding 100+ proteins that the virus hijacks to boost infection.
This project has a long history, spanning from pre-COVID to now! Driven by Manuel Garcia-Moreno and led by @alf-castello.bsky.social
tinyurl.com/54vb842w
Do #intel cards work well as an eGPU with a #Pi5? This question will eventually lead you into the bewilderment zone known as resizing the BAR. I gave up and went with an 8GB AMD to demonstrate progress. Thanks @jeffgeerling.com
www.jeffgeerling.com/blog/2025/us...
An AI will decide the winner of $50k at the @umich.edu #ClawCon
www.start-midwest.com/news/vc-firm...
That's a badass committee member
You gotta tag @lindsaykpino.com for the Skyline pulsed DIA methods!
Love SILAC. SILAC pulldowns are my personal fav. Pulsed SILAC also good. Pulsed SILAC DIA for turnover, wonderful stuff! Yep, love me some SILAC.
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
"That's not a moon!" #StarwarsLife
Good catch. That's a really interesting finding.
We are hiring! The Matthias Mann Lab @mannlab.bsky.social @mpibiochem.bsky.social in Munich has 3 exciting #postdoc openings in proteomics & computational biology. #MSProteomics #PostDoc
postdocprogram.mpg.de
Good!
What is the competing cheaper tech? What are folks using?
Big day for proteomics and in good company! Matthias Mann @mannlab.bsky.social @mpibiochem.bsky.social, John Yates and Ruedi Aebersold receive the 2026 GairdnerAwards for transforming how we measure and understand proteins at scale. #SystemsBiology #Proteomics #Gairdner2026
matrixscience.com is being overwhelmed by millions of HTTP requests from distributed botnets, essentially a distributed denial of service (DDoS) attack. We are forced to mitigate it by restrict access to certain pages of dynamic content.
www.matrixscience.com/whats_new/mi...
#proteomics #massspec
In the US tokens are already becoming part of pay packages.
The day the Affordable Care Act passed was one of my proudest moments as president, because it meant that millions of Americans would have access to health care, some for the first time.
The below story is now out on Nature Methods
www.nature.com/articles/s41...
Really want to avoid the two PCs. Having said that maybe that's the way.
What's everyone's favorite Vanquish Neo error message? Mine is a good old 5045. Love, love me some 5045. 8hrs burned overnight and no real explanation. SOOOOO GOOOOD. Thanks
@thermofishersci.bsky.social
#TeamMassSpec #Proteomics
In the era of the illusion of intelligence can someone please get a Waters M-Class to talk with a Thermo box without issue? Would love to get back on the M-Class platform in our shop. #Proteomics #TeamMassSpec
It's the needle that is of most interest to me
I heard we were struggling to power the 58GW data centers but apparently the hour thing fixed that #lostsleep #grumpykids
I don't think it can. I'm just wondering if anyone has tried to find, or make, a replacement for the needle.
