What should Europe do when demand for #ERC funding keeps rising?
Restrict access or invest in excellence?
Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness
Consider to share & sign - see below 🧪
Congrats Takashi, well earned! 🎉🎉
We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻🔬👨🔬🧬Looking forward to your application!✉️
Congrats Vladimir 🎉🎉
Happy to see the first paper from the lab published in the EMBO J today: link.springer.com/article/10.1...
In it, we reconstitute self-assembling cooperative oligomers of human Ndc80 and Ska kinetochore complexes that stabilise microtubule ends, and study these samples using cryoET and TIRF
PhD position in our lab - 4-year funded by BBSRC and @nrpdtp.bsky.social in collaboration with @earlhaminst.bsky.social and Inspiralis Ltd. Open to UK fee qualifying students - UK citizens and citizens of Ireland (residency requirement), etc biodtp.norwichresearchpark.ac.uk/projects/how...
Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...
I have multiple positions available to join my lab from this summer: #postdoc, #student and #technician. Adverts to follow but see www.saurinlab.com for further details. #senescence, #mitosis, #cellcycle, #phosphorylation are the key areas. Email me if interested.
Congrats for the grant Adrian!
We are delighted to launch the (free!) registration for our 5th AICC symposium, hosted this year in @ucddublin.bsky.social on May 27th.
If you are interested in chromatin, gene regulation or the nucleus please join us!
allirelandchromatinconsortium.ie/annual-meeti...
Our paper is now out in Nature:
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
1/14
Whoop whoop 🎉🎉
I’m very pleased to share our work looking at what controls condensin II cell-cycle dependant activity; a great collaboration with @eugenekimlab.bsky.social, @damlatetiker.bsky.social, Kyle Muir and Kumiko Samejima
www.biorxiv.org/content/10.6...
It’s out! 🥳 Excited to share our new paper (with Kai Walstein, @andrea-musacchio.bsky.social and all others) on the role of M18BP1 in CENP-A loading!
“M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans”
link.springer.com/article/10.1...
🎉🎉🎉
Additional complementary evidence
by Arianna Esposito Verza, @andrea-musacchio.bsky.social et al
link.springer.com/article/10.1...
and by Anais Pillan, Lionel Pintard @ccdlab.bsky.social et al
link.springer.com/article/10.1...
in our sister journal @embojournal.org
See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers!
link.springer.com/article/10.1...
We are recruiting a Postdoc in computational biology, together with @mariasecrier.bsky.social
4yr, fully funded by @cancerresearchuk.org, ideal for Postdocs wanting to develop their independence
Applications open now: www.imperial.ac.uk/jobs/search-...
Dear job rejection letters that are sent on the 22nd and 23rd of December, many thanks for making my Christmas holidays even happier.
Congrats!! 🎉🎉
differential contribution of H3K9 methyltransferases to boundaries at satellites
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
Congrats @jansenlab.bsky.social, @bencarty.bsky.social and team! 🎉🎉
Join us in Lunteren, the Netherlands on March 5 & 6, 2026 for the 32nd Dutch Cancer Biology meeting. We have two fantastic keynote speakers: @andrea-musacchio.bsky.social and @colindascheele.bsky.social and the rest of the program will be by early-career scientists. Info: www.dutchcancerbiology.nl
I feel you ❤️
The Wilkinson Lab is open for science! @mskcancercenter.bsky.social
🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬
annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
When is it coming to PS? 🤩
I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...
Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵
www.anthropic.com/news/claude-...
Structures from AlphaFold3 - while often impressively good - tend to fail representing the dynamic ensembles accurately. And often parts of the structure are not correct. Adding experimental data, directly in AlphaFold's diffusion step, provides physically realistic protein ensembles. This image shows two cases where AlphaFold3-only structures were largely improved by guiding with experimental data.
📢 New preprint:
Experiment-guided AlphaFold3 resolves accurate protein ensembles.
doi.org/10.1101/2025...
AlphaFold3 is incredible, but has crucial limitations: it typically collapses to a single conformation, ignoring the inherent dynamics of proteins. And it can be wrong. Here's a solution. 🧵👇
