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Posts by Joseph Hughes

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FULLY FUNDED PhD - Vector-imposed constraints on the evolution and diversity of bluetongue virus at University of Glasgow on FindAPhD.com PhD Project - FULLY FUNDED PhD - Vector-imposed constraints on the evolution and diversity of bluetongue virus at University of Glasgow, listed on FindAPhD.com

Fully funded PhD in virology - CVR & The Pirbright Institute
Vector-imposed constraints on the evolution and diversity of bluetongue virus. J. Hughes, P. Johnson, M. Guimera Busquets, C. Sanders, N. Forrester-Soto
Deadline for application: 08/05/2026 - tinyurl.com/BTVevolution

1 day ago 0 0 0 0
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Great delivery by Sarah Little from @grovearmada.bsky.social team @microbiologysociety.org : Scalable Screening of AI Designed Binders that Prevent Virus Entry

5 days ago 5 3 0 1
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Fleming Prize Lecture @microbiologysociety.org : Unravelling Respiratory Viral Infections: from Bedside to Bench and Back

Professor @drtoniho.bsky.social (MRC-University of Glasgow Centre for Virus Research)

1 week ago 9 1 2 1

He's almost finished his PhD so if looking for a computational biologist with phylogenetics and structure biology prediction experience, let him know.

1 week ago 0 0 0 0
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Great presentation from @ulad-litvin.bsky.social @microbiologysociety.org annual conference: How far can AlphaFold go? Lessons from modelling virus–host protein interactions using AlphaFold3.

1 week ago 11 3 1 1

​A huge thank you to the team at the MRC-University of Glasgow Centre for Virus Research (CVR) @cvrinfo.bsky.social: @ulad-litvin.bsky.social, @bljog.bsky.social, @spyroslytras.bsky.social, Alexander Jack, and @davidlrobertson.bsky.social.

2 months ago 2 1 0 0
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📢 New preprint is out on bioRxiv 📢:

How much does virome prep influence our view of the human gut virome?

Short answer: a lot.

Long answer:
doi.org/10.1101/2025...

Different methods lead to distinct community structures, richness, and major virus-host abundance patterns.

🧵 1/5

4 months ago 26 13 2 0
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FindAPhD : The MRC-University of Glasgow Centre for Virus Research (CVR) PhD Funded Programme at University of Glasgow Apply for a PhD: The MRC-University of Glasgow Centre for Virus Research (CVR) PhD Funded Programme at University of Glasgow

Are you fascinated by viruses? Would you like to design your own original research project in the UK's largest virology centre? Why not come and do a PhD @cvrinfo.bsky.social - application deadline 6th Jan 2026 (1/1): www.findaphd.com/phds/program...

4 months ago 12 14 2 1
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What makes bird flu spill over to humans? 4y funded PhD in the genomics and molecular virology behind zoonosis of avian influenza A virus, working with @tompeacock.bsky.social and others between Liverpool, Pirbright, and Uppsala!

open to applications until next week!

4 months ago 11 5 2 0

I think more studies need to be done in humans as it seems likely that antipyretics do more harm than good in some situations. Lowering body temperature could be neutralising a powerful antiviral defence.

Thanks for reading this thread.

4 months ago 12 3 3 0
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Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...

How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵

www.science.org/doi/10.1126/...

4 months ago 200 90 6 6

PhD position (Glasgow, UK)
Build lightweight AI tools supporting One Health decision-making.
with @kirstynbrunker.bsky.social @bljog.bsky.social @jakelever.bsky.social
at @sbohvm.gla.ac.uk
More details: http://iddjobs.org/jobs/2420

5 months ago 0 5 0 0
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Viro3D: a comprehensive database of virus protein structure predictions | Molecular Systems Biology imageimageViro3D provides proteome-level, high confidence AI-protein structure predictions for >4,400 viruses, allowing mapping of form and function across the human and animal virosphere. Viro3D i...

New exciting resource published!! The Viro3D paper is out, describing our comprehensive database of predicted virus protein structures! 💻🧬

Work with @ulad-litvin.bsky.social , @grovearmada.bsky.social , Alex Jack, @bljog.bsky.social , @davidlrobertson.bsky.social

www.embopress.org/doi/full/10....

6 months ago 45 21 1 0

Team effort from @uofgmvls.bsky.social @cvrinfo.bsky.social

Science: @ulad-litvin.bsky.social @spyroslytras.bsky.social @davidlrobertson.bsky.social and @bljog.bsky.social

Website: Alexander Jack

Funding: @medresfdn.bsky.social @ukri.org @wellcometrust.bsky.social @royalsociety.org

6 months ago 7 1 0 0
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Kieran Lamb from @davidlrobertson.bsky.social gets best poster prize at EVBC meeting in Lisboa

11 months ago 5 1 0 0
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The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2 Recombination-aware evolutionary analyses of the entire genomes of SARS-CoV-1-like and SARS-CoV-2-like viruses indicate that SARS-CoV-1 and SARS-CoV-2 descend from bat coronaviruses that circulated as...

📄 NEW | Genetic Study shows that Wildlife Trade sparked COVID-19 Virus Emergence in Humans

SARS-CoV-2 arrived in Wuhan too quickly for bat hosts to have carried it there.

cell.com/cell/fulltex...

gla.ac.uk/research/az/...

@davidlrobertson.bsky.social
@spyroslytras.bsky.social
@bljog.bsky.social

11 months ago 11 10 1 0
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US joins Russia to vote against UN resolution condemning Russia’s war against Ukraine | CNN Politics The United States joined Russia to vote against a UN General Assembly resolution condemning Russia’s war against Ukraine Monday in a stunning shift from years of US policy.

For the US to side with Russia and North Korea to oppose a UN resolution condemning the illegal invasion of Ukraine defies all common sense and adds insult to the countless injuries suffered by the brave Ukrainian people. edition.cnn.com/2025/02/24/p...

1 year ago 62406 14153 3602 1344
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‘I do not want a fellowship that can include such actions.’

Elon Musk's fellowship is undermining the purpose of the Royal Society, writes resigning fellow @andrewmillar.bsky.social.

In this piece, he tells us why he feels enough is enough.

www.researchprofessionalnews.com/rr-news-uk-v...

1 year ago 43 23 0 4
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Pathogen genomic surveillance and the AI revolution | Journal of Virology Genomic pathogen sequencing during the COVID-19 pandemic highlighted the critical role of surveillance in understanding the persistence of SARS-CoV-2 in the human population despite high levels of pro...

Recently we have been doing lots of work on how modern #AI methods can be applied to studying virus evolution, so it felt like great timing to write a perspective about it!

Very happy to see our paper as editor's pick in JVI!🥳🥳

doi.org/10.1128/jvi....

1 year ago 32 17 2 1
2025-26 Bloomsbury Colleges PhD Studentships | LSHTM The Bloomsbury Colleges group was set up in 2004 and consists of five institutions: Birkbeck, London School of Hygiene & Tropical Medicine (LSHTM), the Royal Veterinary College (RVC), the School of Or...

🎺 PhD studentship available at @lshtm.bsky.social and RVC! @influenzal.bsky.social and I are advertising for a project to investigate the unexpected phenomenon that mutagenic antiviral drugs can give rise to viruses with hundreds of mutations which are still viable. 🧵
www.lshtm.ac.uk/study/fees-a...

1 year ago 45 32 1 2

This paper has been a side project for quite a few years now, so I'm extra happy to see it published!!
big thanks to co-lead Sej Modha as well as @bljog.bsky.social and Richard Orton + all the experts who gave valuable feedback at conferences and over the internet! 😁😁

1 year ago 0 1 1 0
A view of the Garscube campus from above

A view of the Garscube campus from above

A QR code for accessing further information and registration

A QR code for accessing further information and registration

As a WOAH Collaborating Centre, we’re excited to announce our 8th annual Viral #Bioinformatics & #Genomics training course from 16th - 20th June 2025! 🧬
@cvrinfo.bsky.social
📅 Register by 30 April:
👉 bit.ly/VBGCourse2025
📲 Or scan the QR code to join.

1 year ago 5 3 1 0
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Person dies from rabies in Northern Kentucky, first rabies death in state since 1996 The victim, a resident of Northern Kentucky, succumbed to the disease after receiving medical treatment in both Kentucky and Ohio.

Another human rabies death in the US:

1 year ago 1 2 0 0
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Concurrent Severe Fever with Thrombocytopenia Syndrome Virus Outbreaks on Multiple Fox Farms, China, 2023 The role of farmed animals in the viral spillover from wild animals to humans is of growing importance. Between July and September of 2023 infectious disease outbreaks were reported on six Arctic f...

Another virus outbreak (Severe Fever with Thrombocytopenia Syndrome Virus -SFTSV) associated with fur farming. It needs to stop. www.tandfonline.com/doi/full/10....

1 year ago 68 31 5 1
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Not sure of the original source of this, but the depiction with the final domino set to crush the pusher is devastatingly accurate.

1 year ago 3657 1800 50 118
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Why Sweden Clears Snow-Covered Walkways Before Roads — Streetsblog USA It's part of "gender-balanced" policy that reflects the fact that women walk more than men.

“Many Swedish cities, including Stockholm, prioritize snow clearance very differently. They now clear walkways & bike paths first, especially those near bus stops & primary schools. Next, they clear local roads, & then, finally, highways.” Via @usa.streetsblog.org
usa.streetsblog.org/2018/01/24/w...

1 year ago 718 195 19 22

An exciting resource we put together with Ulad Litvin, @grovearmada.bsky.social Alexander Jack, @davidlrobertson.bsky.social and @bljog.bsky.social bsky.app/profile/grov...

1 year ago 7 4 1 0
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✨ This was a huge team effort by Ulad Litvin, @spyroslytras.bsky.social, Alexander Jack, David Robertson and @bljog.bsky.social

Thank you to our funders MRC @ukri.org , @medresfdn.bsky.social, @wellcometrust.bsky.social.

We can't wait to see what discoveries you'll make with Viro3D in 2025! 🚀

1 year ago 4 2 0 0
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NEW Publication!😄

Here, we show how #PhyKIT — a broadly applicable toolkit for #phylogenomics — can be used to construct phylogenomic data matrices (& quantify biases therein), detect anomalies in predicted orthology, calculate gene-gene coevolution, & more!

🔗: tinyurl.com/yc5ja4xz

1 year ago 163 63 2 2

So happy to see that there are still people with a moral compass

1 year ago 1 0 0 0