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Posts by Jan Seebacher

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💫 We're hiring! The Computational Biology Facility is looking for a Computational Proteomics Scientist to collaborate on cutting-edge proteomics projects, develop new analytical approaches, and publish impactful research.
Apply by April 12 at: www.fmi.ch/education-ca...

2 months ago 13 13 0 2
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🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...

7 months ago 61 66 0 4
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How DNA packaging controls the “genome’s guardian” Our cells tightly pack DNA into structures called nucleosomes, which protect DNA but also hide important sites. The key cancer-fighting protein p53 can still access these hidden sites, especially at n...

Our cells pack DNA into tiny bundles that hide important parts. Researchers at the FMI and EPFL found this packing affects how the cancer-fighting protein p53 works, revealing new insights into cancer. www.fmi.ch/news-events/...

8 months ago 7 4 0 0
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A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin Transcription factors (TFs) are key regulators of gene expression, yet many of their targets and modes of action remain unknown. In Schizosaccharomyce…

www.sciencedirect.com/science/arti...

I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬

Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌

1 year ago 23 12 2 1
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We're hiring! Our IT Team is looking for a Linux Systems Engineer to support scientific computing and big data management. Apply here: www.fmi.ch/education-ca...

1 year ago 5 8 0 0

Want to follow some of our current members and alumni? Check out the FMI Starter Pack 👉bsky.app/start/did:plc:g3dn6h22ro...

1 year ago 7 3 0 0
Friedrich Miescher Institute, open position Friedrich Miescher Institute, open position

Permanent position for a Linux Systems Engineer: Are you fond of scientific computing and/Linux/HPC and would enjoy working in a vibrant research environment? Have a look at our job opening: www.fmi.ch/education-ca...

1 year ago 6 11 0 0
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📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

1 year ago 110 117 4 7
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Decoding protein interactions: A step toward personalized medicine Investigating how proteins interact is key to understand how cells work and communicate. In a new study — the first of its kind to examine the effects of all possible mutations in a protein across int...

In a new study published in Nature Communications, researchers led by Guillaume Diss have provided key insights into how protein interactions are governed and how mutations influence cellular functions—work that might help advance personalized medicine.

1 year ago 6 5 0 1

Thanks Jane! That was a fun project.

1 year ago 0 0 0 0
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New tool to map protease specificity may pave the way for improved treatments FMI researchers have developed a new tool that maps how proteases —enzymes that process proteins— cut their targets. This innovation offers new insight into the highly selective nature of proteases, w...

Researchers in @labgrosshans.bsky.social & their collaborators developed a tool that maps how proteases—enzymes that process proteins—cut their targets. The work, published in Molecular Systems Biology, could revolutionize drug design for conditions like diabetes. www.fmi.ch/news-events/...

1 year ago 5 3 1 0
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For over 50 years, the FMI has proudly advanced biomedical research and training. As times evolve, so do we: we've joined Bluesky! Follow us for the latest updates and news about our institute 🌤️

1 year ago 12 4 2 0

This works really well, highly recommend it! Thanks for this new workflow.

1 year ago 1 1 0 0
Friedrich Miescher Institute, open position Friedrich Miescher Institute, open position


🔬 Join FMI! We’re seeking a proteomics expert to develop cutting-edge mass spectrometry applications. Collaborate with top researchers in Genome Regulation, Multicellular Systems, and Neurobiology.
Apply now or share this job ad in your network!
#proteomics #CoreFacility

www.fmi.ch/education-ca...

1 year ago 5 3 0 0