The spatiotemporal dynamics of postnatal vascularization in the mouse brain Whole-brain tissue clearing and spatial transcriptomics were applied to map postnatal vascular development in the mouse brain, identifying three coordinated phases that link vascular growth to neurona...

The absolute dream paper for any #cerebrovascular developmental biologist !! Congrats to @nicolasrenier.bsky.social, @alexdubrac.bsky.social and their teams !

CONGRATS!!🎉

New study clarifies the role of Angiopoietin 2 in the brain vasculature #Cerebrovascular 👇

Look at this beautiful preprint ! by Neil Dani & team #ChoroidPlexus #BrainBarrier www.biorxiv.org/content/10.6...

What’s the philosophical relevance ?

The neurovascular impulse response function differentially reflects intrinsic neuromodulation across cortical regions - Nature Neuroscience A new optical imaging study demonstrates that norepinephrine and the state of arousal influence hemodynamic correlations across cerebral cortex, calling for a conceptual shift in interpreting function...

New insights into brain imaging by @annadevor.bsky.social just dropped 🧠✨ This study shows that neuromodulators, especially norepinephrine, actively reshape how neural activity translates into blood flow signals across the cortex. A powerful step toward more accurate brain mapping! #cerebrovascular

Sleep alters neurovascular and hydrodynamic coupling in the human brain | PNAS Sleep is essential for maintaining brain tissue homeostasis, which is facilitated by enhanced cerebrospinal fluid (CSF) solute transport. Infraslow...

New results show that, in addition to neural changes, sleep involves nonneural processes such as vasomotor-driven hydrodynamic waves 🤩 #Cerebrovascular #sleep

🚨 For astrocyte lovers 👇👇

You can be proud for sure ! 👏🏻👏🏻

Way to go team! 💪💪💪

Please consider joining us in May by registering ! Abstract submission deadline extended to March 12th! The last 48hrs to submit your work 😇 Register until April 30th to attend our 3rd CANGlia symposium, with Cagla Eroglu as keynote speaker, and excellent symposia 😎 #Glia #neuroscience #conference

🚨Our new paper in Circ Research on the cover + 📖 editorial by Dr. Jackson🔗https://tinyurl.com/2d6hxa83
👏 Danielle Jeffrey tinyurl.com/bdduwe43 collaboration with @osamaharraz.bsky.social Lab
♀️ Female mice show lower hippocampal tone
🌸 Estrogen-dependent⚡️ SK channels dominate
💡 Ludeman Family Center

Thinking of moving to this too, after spending way too much much on a pro rig 🤕

State of the onion

Yup, perfect representation of a bully

Wow can’t wait to read! Congrats!

Wrapping up my visit to UVA, had a great time and learned about a lot of exciting stuff! Thanks @eyolab.bsky.social for hosting me!

Bien connus

Je vois que ton passage à Bordeaux a porté ses fruits! J’imagine que le 🍷 a aidé 😇

Professional advice: when celebrating your 10th year lab anniversary🍻, bring your trainees to an axe throwing club, so they can release all the anger accumulated. Let them imaging your face is on the wall 😂

NMDA receptors coordinate brain vascular development via neuron-to-endothelial tip cell crosstalk in zebrafish - Nature Communications Neurovascular interaction is critical for normal brain vascular development. Here, the authors show that neuronal NMDARs regulate brain vascular development via VEGF-induced global Ca2+ activities of ...

Cool neurovascular paper in #zebrafish #cerebrovascular #development

New findings suggesting that PROX1 compromises BBB integrity by negatively regulating BBB-associated Wnt signaling. #BBB #BloodBrainBarrier #cerebrovascular

“Elon Musk is part of the administration” that says it all… I feel sorry for all my friends south the Canadian border

We actively encouraging top-quality international candidates to apply. The Impact+ program emphasizes research excellence in areas of Canada's strategic priorities, and significant potential to move research discoveries into tangible economic and social benefits.

The University of Ottawa is recruiting international talent through a special program named "Canada Impact+ Research Chairs". See link at the very bottom.

🎉 New Publication in @pnas.org

Excited to share our lab’s latest research article: PIP₂ Corrects an Endothelial Piezo1 Channelopathy
pnas.org/doi/abs/10.1... (Open Access)

thanks Ciaran!

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2 deficient murine astrocytes Autism Spectrum Disorders (ASD) are associated with metabolic dysregulation. While astrocytes are integral to cerebral metabolism, their molecular and functional changes in ASD are poorly known. Using...

New preprint from the lab! For those who love astrocytes 🤩. We welcome feedback! #preprint #openaccess #astrocytes #autism

Happy holidays and best wishes from our lab!

Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse - Molecular Psychiatry Molecular Psychiatry - Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse

A beautiful paper from my friend @naguibmechawar.bsky.social's team ! www.nature.com/articles/s41... #cerebrovascular