Genetic testing and pancreatic cancer: Why is it important? By Eric Traub | Northside Hospital Cancer Institute Pancreatic cancer: arguably the most haunting pair of words in the medical world. Numerous high-profile people have succumbed to pancreatic cancer a...

November is Pancreatic Cancer Awareness Month 💜

It’s the deadliest of the common cancers due to late detection.
Researchers stress genetic testing - hereditary risk matters. Know your family history. Advocate for early detection. 💜
Read more 👉 shorturl.at/eKuTB

#PancreaticCancer #GeneticTesting

We’re proud to present the current Council members of The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), driving progress in research, collaboration, and patient care worldwide.

Learn more about us👉 shorturl.at/6cyJV

#Genetics #GIHealth #HereditaryGICancer #InSiGHT

We had the 3rd meeting of the UK EOCRC Research Consortium in beautiful Edinburgh yesterday supported by British Society of Gastroenterology (BSG) and @bowelcanceruk.bsky.social attended by over 50 UK academics - celebrating our first project funding success only 1 year after foundation

Diagnostic yield of colonoscopy in Lynch Syndrome

We demonstrate a high adenoma burden with distinct phenotypic and gene-specific characteristics in a UK LS population undergoing high quality surveillance

fg.bmj.com/content/earl...

A woman's cancer seemed incurable. Identifying a rare genetic condition saved her life. Chemo and surgery failed to treat Diane Davis' advanced cancer. Things seemed hopeless until genetic testing found an unlikely culprit.

Chemo and surgery failed to treat one woman's advanced cancer. Hope emerged through genetic testing, revealing an unexpected cause. www.cbsnews.com/news/advanced-ovarian-ca...

We are looking for our new Tom Smith Clinical Research Fellow in #LynchSyndrome and Early Onset ColorectalCancer with @trevorgraham.bsky.social in translational science … thanks to 40tude curing colon cancer for supporting this fellowship - get in touch! @stmarksgenomics.bsky.social @icr.ac.uk

Baby Aspirin and Cancer Prevention in Lynch Syndrome: New CaPP3 Results Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

📣Missed #CGAIGC25 this year?

Catch the short discussion between Prof Sir John Burn & @swatipatelmd.bsky.social sharing long-awaited CaPP3 results, a follow-up to the landmark CaPP2 trial showing aspirin’s 💊role in lowering cancer risk in #LynchSyndrome
👉 tinyurl.com/msshdb5b
#HereditaryGICancer

National Family History Month: A Reminder for Providers and Genetic Counselors! October’s National Family History Month is an important opportunity to emphasize how family history drives cancer risk assessment, genetic referrals, and prevention. Even with growing access to geneti...

🧬 October = National Family History Month!

Read the blog📜👉 tinyurl.com/bdhjjv83

Reminding us that even in the era of🧬testing, 👪history is still the foundation of hereditary cancer care. Asking the right❓& sharing results can save lives across generations.

#HereditaryGICancer

Day 3 of Hereditary Cancer Awareness Month 🧬 also highlights Gynecologic Cancer Awareness Month 💜.

Watch the video on ctDNA for Endometrial Cancer 🎥 tinyurl.com/3fajahme + listen to our podcast on Lynch syndrome & NCCN updates 🎧 tinyurl.com/2jmvmt7t

#HereditaryGICancer #LynchSyndrome

I have been able to connect with other people with Lynch Syndrome, and this has helped me so much, as I felt so alone when I was first diagnosed in 2024.

While the underlying genetic defects differ significantly between Lynch syndrome and FAP, the pathogenetic mechanisms in these two disorders represent canonical pathways of young-onset colorectal cancer carcinogenesis.
https://www.nature.c

Thank you Matthew for contributing to Lynch Syndrome research 👏

Back to London early as today’s my date for ongoing Lynch Syndrome bowel/prostate cancer research project at Royal Marsden. I don’t have the genetic flaw so am part of the control group. Important stuff x

Frank Sinicrope MD of Mayo Clinic Comprehensive Cancer Center will present new subgroup findings from the #ATOMIC trial (Alliance A021502) in a poster session at #ESMO25. Data highlight outcomes in sporadic vs. Lynch syndrome–related dMMR colon cancer. Sunday, Oct 19. @ALLIANCE_org #NCI #NCTN #CRCsm

Low Yield of Genetic Testing in Serrated Polyposis Syndrome

journals.lww.com/ctg/fulltext...

Critical Evaluation of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | JCO Oncology Practice

Critical Evaluation of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | JCO Oncology Practice ascopubs.org/doi/10.1200/...

Annual COVID Vaccines Save Lives, New Study Shows A new study shows that receiving an updated COVID vaccine reduced people’s risk of severe disease and death in all age groups, regardless of immunity from prior infection or vaccination

New study shows COVID vaccines:
💉Reduced people’s risk of ER by 29%
💉Reduced risk of hospitalizations by 39%
💉Reduced the risk of death by 64%
💉Vaccination was effective in all age groups and “in persons with or without major chronic conditions.”
www.scientificamerican.com/article/new-...

CIDRAP Op-Ed: Why the CDC director is wrong about the MMR vaccine

Excellent op Ed about the issues with single vaccines published in response to Trumps Statement about single shots for Measles, mumps and rubella as well as CDC call for single vaccine manufacturer 🧵🧪#HealthPolicy

Join our free, open access webinar with the Young European Hematology Association & @yefis-immunology.bsky.social, featuring 3 presentations on CAR T-cells!

📅 19 November 14:00-15:30 CET
🌍 Zoom

us02web.zoom.us/webinar/regi...

🚨 It’s here!
The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live!
🔗 Check out the full program: insight2026.org/scientific-programme
🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines

#InSiGHT2026 #HereditaryCancer #GICancerResearch

DNA mutagenesis driven by transcription factor competition with mismatch repair Competition between transcription factors and mismatch repair machinery drives localized hypermutation at regulatory elements, with implications for cancer and genome evolution.

I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...

Shouting from the rooftops: how a powerful patient story about bowel screening inspired others to take action A social media campaign highlighting the power of co-designing with our screening participants to share human stories.

Mary Kennedy's powerful story about bowel screening inspired thousands of others to take action.

Her message is simple: even if you feel well, screening can save your life.

Read how her story made an impact: tinyurl.com/PPP-story-ca...

#ChooseScreening #BowelScreen

Today, we launch #CancerNeedsTrials.

Cancer trials give patients access to tomorrow’s treatments today — but in Ireland, access is too limited.

We’re calling on the government to invest so more patients can benefit. Add your voice: bit.ly/4nos5iL

#CancerNeedsTrials

Blame-Ridden Language in Medicine Problematic Language: Words like claims, denies, and failed treatment subtly blame or cast doubt on patients. Dehumanizing Terms: Using labels like diabetic or ep…

lynchsyndromeireland.com/2025/09/28/b...

Our results support universal and paired somatic and germline multi-gene panels for all EOCRC patients, regardless of MMR status or family history

onlinelibrary.wiley.com/doi/10.1002/...

Low Yield of Genetic Testing in Serrated Polyposis Syndrome - PubMed Genetic testing demonstrated a low diagnostic yield in this SPS cohort, suggesting undefined genetic risk or involvement of other pathophysiological factors. Therefore, genetic testing appears to have...

Genetic testing appears to have limited utility in SPS patients and may primarily identify those with an incidental diagnosis of Lynch syndrome

pubmed.ncbi.nlm.nih.gov/41002021/

Trump attacks Tylenol as officials unveil highly contentious conclusions on autism President says acetaminophen – also known as paracetamol - increases risk when taken by pregnant women, assertion contradicted by research

So the politicisation of health continues in the States and I want to highlight a few key things 🧪🧵

Doing Cancer Wrong doctor cancer blog

Doing Cancer Wrong:
I have an innate tendency to do precisely the opposite of what society expects from me.
adventuresofasickdoctor.blogspot.com/2025/06/doin...

The unexpected value of communicating science to the public Nature Reviews Neuroscience - As a group, our scientific community has a responsibility to unpack the ‘what’ and ‘why’ behind our work for the public, not least because much...

Fantastic piece in Nature Reviews Neuro by @nicolecrust.bsky.social on the importance of science communication. My take? Everything matters - just do something. It will make a difference for how science is valued and trusted, how community understands. Let's get out there and communicate! 👏