After 3 years, I’m very happy to share my postdoc work which has been published in @natcomms.nature.com 🎉

doi.org/10.1038/s414...

✨ Thank you @arhelnathalie.bsky.social for your guidance and support !

#influenza #NPC #RANBP2 #Nup358 #Inflammation #ANE #AcuteNecrotizingEncephalopathy
#virology

Unravelling the diversity of RANBP2: protein isoforms and implications for cellular function and human disease RANBP2 (also known as Nup358) is the largest nucleoporin of the nuclear pore complex (NPC), where it constitutes the main component of the cytoplasmic…

RANBP2 is a major susceptibility factor in Acute Necrotizing Encephalopathy. But is it a single protein, or are there other isoforms with distinct roles we should be studying?
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...

Super excited for the ANEmone colloque tomorrow reuniting families, clinicians and scientists in order to better understand ANE1 !
@arhelnathalie.bsky.social

Merci à la SFV de m’avoir permis de présenter une partie de mes travaux sur RANBP2 aux #JFV2025 ! À l’année prochaine à Toulouse !

Soutien à l'organisation d'une rencontre de patients atteints d'ANE1 - fonds guilhem En avril prochain, cet événement aura pour but de promouvoir un partage d’expériences et d'apporter un soutien grâce à la rencontre entre familles, chercheurs et médecins autour de l'ANE1.

Acute Necrotising Encephalopathy 1 is a rare disease that triggers devastating brain damage in young children following a viral infection. Please would you consider giving to help 19 kids with ANE1 from 🇺🇸🇨🇦🇪🇺 attend a science-patient conference in 2025 🙏 #GivingTuesday
fondsguilhem.fr/projet/souti...

RANBP2 regulates influenza RNA replication and nuclear export, triggering hyper-inflammation, offering insight into Acute Necrotizing Encephalopathy pathogenesis
doi.org/10.1101/2025...

The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection www.biorxiv.org/content/10.1101/2025.03....

The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection Influenza virus infections can cause severe complications such as Acute Necrotizing Encephalopathy (ANE), which is characterised by rapid onset pathological inflammation following febrile infection. H...

Our latest collaborative study with the Pasteur Institute and University of Toronto on the role of RANBP2 in #influenza -associated hyperinflammation #AcuteNecrotizingEncephalopathy @aneinternational.bsky.social @ribonucleicacids.bsky.social @irim-life.bsky.social
www.biorxiv.org/content/10.1...