A very difficult Friday for early career scientists.

This administration is making us dread Fridays.
That is a fundamental wrong.
TGIF is offended.
Just rude. 😑

Very excited to join this fantastic group! 🧫🦠🧪 #microbiome #openaccess

Thousands gather across U.S. in Stand Up for Science events Scientists rally across the country in response to layoffs and funding cuts ordered by the Trump administration

Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4

Man in yellow speaking to crowd

Francis Collins at the Stand up for Science Rally

image of the livestream

LIVE STREAM UP!

m.twitch.tv/standupforsc...

Large Quantities of Bacterial DNA and Protein in Common Dietary Protein Source Used in Microbiome Studies Diet has been shown to greatly impact the intestinal microbiota. To understand the role of individual dietary components, defined diets with purified components are frequently used in diet-microbiota...

When you do #Metagenomics and #Metaproteomics with mice fed a standard diet with Casein make sure to account for the large amount of dead L. lactis that comes with the diet
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

🧪🧫🦠

The best of multi-omics on plant microbe interactions! Very exciting work!

😱

Lab at the speakeasy

The lab dressed up, had great food and then drinks at the Speakeasy, celebrating @microberich.bsky.social leaving the lab and heading to UVA for her postdoc. World, look out for her future endeavor!

Let's increase #klebclub chatter on 🔵🦋!
Klebsiella aficionados add your handle below and we will build a starter pack.

🔁 to spread the word

A thread with some new starter packs in genomics and bioinformatics 🧵 1/13...

Would love to be included!

A touch of mechanism

🙋‍♀️ would love to be added!

What an amazing celebration! Thank you all, I will miss the Lee lab and the friends made along the way.

Eubacterium rectale detoxification mechanism increases resilience of the gut environment https://www.biorxiv.org/content/10.1101/2024.05.09.593360v1 Lachnospiraceae members were highly detected in dysbiotic IL-10 KO mice that displayed similar physi

Eubacterium rectale detoxification mechanism increases resilience of the gut environment www.biorxiv.org/content/10.1101/2024.05....

Eubacterium rectale detoxification mechanism increases resilience of the gut environment bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Beyond thrilled to see my 2nd Chapter hot off the preprint presses! This project examines Eubacterium rectale for alleviation of gut epithelium ROS damage through biosynthesis of the antioxidant glutathione. Check it out! #microbiomesky #IBD #microsky 🧪🧫

Very exciting to host our seminar speaker and one of my mentors @manuelkleiner.bsky.social! Thanks for coming by and discussing some great science 🧪 🦠🧫🧬 #Microsky #PhDsky

In this study we show that microbial contamination in common mouse diets can lead to incorrect conclusions about microbiome composition.
"Large Quantities of Bacterial DNA and Protein in Common Dietary Protein Source Used in Microbiome Studies"
www.biorxiv.org/content/10.1...

A very interesting book comes to mind here “The demon under the microscope” goes into the development of sulfas and the surrounding historical context! WWII had quite the impact on sulfa development.

We are now moving into mechanistic study! Descriptive microbiome to mechanism in the works - stay tuned for my other chapters coming soon!! #MicrobiomeSky

Next, to prove that, we isolated and cultured these MAGs and showed that they can indeed use cysteine. We also showed that MAGs/isolates from dysbiotic mice can used cysteine more effectively for growth than MAGs/isolates from healthy mice.

I performed network analyses showing the high association of host cysteine metabolizing genes and MAGs of interest. This drives our thought that the MAGs may be “stealing” valuable cysteine from the host.

We found that IL-10KO vertical transmitted dysbiotic mice are scavenging for cysteine that may aid in gut immune homeostasis. On the other hand, we assembled MAGs, and found several MAGs that are highly detected in dysbiotic mice have genomic capability of metabolizing cysteine.

So excited that my thesis first chapter is live in ASM's
#mSystems journals.asm.org/doi/10.1128/... We use a bunch of techniques to show that gut microbial populations may be “stealing” valuable amino acids from the mice host, resulting in persistent gut inflammation! #PhDSky #MicroSky 🧪🦠🧫🧬

Precision Prescribing for Colon Cancer Based on Gut Microbes This student story was published as part of the 2023 NASW Perlman Virtual Mentoring Program organized by the NASW Education Committee, providing science journalism practice and experience for undergra...

Excited to see this article now online! Bringing attention to the need of revolutionizing cancer treatments and how our gut microbes may play a role in personalized care! 🦠🧪🧫www.nasw.org/article/nasw-science-wri... #SciComm #PhDSky

😱 adding to the list!

With my little bit of free time, decided to try a hand at watercolors of some of my favorite bacteria with various stains! 🦠 🧫🧪
#PhDSky #SciArt