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Posts by Julien Colombani & Ditte Andersen lab

@carlsbergfondet.dk @ucph.bsky.social

1 month ago 2 0 0 0
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Join us for a day of talks, posters, and discussions, featuring a morning joint lecture with Nobel Laureates Eric F. Wieschaus and Christiane Nüsslein-Volhard!
Date: Monday, May 4th, 2026
Location: University of Copenhagen, Mærsk Tower
sites.google.com/view/emergin...
Free to participate

1 month ago 23 20 1 0
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🚨 HUGE NEWS for the Nordic fly community!
​Nobel Laureates Eric Wieschaus & Christiane Nüsslein-Volhard are coming to the Mærsk Tower on May 4th! 🇩🇰
sites.google.com/view/emergin...
Funded by @carlsbergfondet.dk

2 months ago 3 1 0 0

Congrats!

4 months ago 0 0 0 0
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The students are also affected by layoffs at the Faculty of Science We fear cancelled courses and poorer quality of education, and we don't think the management acknowledges the gravity of the situation.

Cuts to the Faculty of Science will lead to poorer education programmes, write student reps on the Study Board of Biology:
uniavisen.dk/en/the-stude...

5 months ago 4 1 0 0
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Excited to share our collaborative PhD project with Adam Dobson (Adam.Dobson@glasgow.ac.uk) on interorgan signalling in the ageing gut. Please contact Adam If you are a highly motivated student wanted to work on a super exciting Fly project.

6 months ago 4 5 0 0

@epimechfc.bsky.social

6 months ago 1 0 0 0
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Redirecting

Please read the very nice complementary story from our colleagues @corderolab.bsky.social
doi.org/10.1016/j.de...

6 months ago 3 0 0 0

Nice team work from our PhD student Duncan Mackay with the precious help of @alphyjohn.bsky.social and colleagues, and a great collaboration with Matteo Rauzi lab

6 months ago 1 0 0 0
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Pvf1-Pvr-mediated crosstalk between trachea and gut guides intestinal stem cell migration to promote gut regeneration - Nature Communications Adult stem cells often reside in specialized niches that they exit upon injury. Here they show that in Drosophila, after damage the gut-associated trachea produces the PDGF-VEGF-related ligand Pvf1, which acts as a guidance cue directing ISC migration toward injury sites.

Excited to share our last paper describing how intestinal stem cell migration promotes gut regeneration!
www.nature.com/articles/s41...

6 months ago 15 8 7 1
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- Rouba, Nhi and Lizzie have posters in session 1 & 2

7 months ago 2 0 0 0
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We are looking forward to seeing you at the @edrc2025.bsky.social
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions

7 months ago 7 3 1 0
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2 post-doc positions open in the lab to do research on inter-organ signalling in regeneration and cancer in flies and mice.

8 months ago 11 11 0 0
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Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila Robust and controlled intestinal regeneration involves reciprocal interactions between the intestinal epithelium and its microenvironment. Here, we id…

Very happy and proud to share the latest work from our lab.
Neuroendocrine control of intestinal regeneration through the vascular niche.
www.sciencedirect.com/science/arti...

9 months ago 21 10 1 0
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Not yet!

11 months ago 2 0 0 0
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Great meeting!

11 months ago 6 1 1 0

Great works of @rustenlab.bsky.social and @Basler lab independently showing how premalignant cells can exploit Toll-NF-κB signaling, in concert with oncogenic Ras, to enable unchecked growth #Drosophila Papers: plos.io/4jqpmUh and plos.io/3RGWESS Primer: plos.io/3GyUeU0

11 months ago 5 1 0 0
Schematics Top: While Toll-NF-κB pathway activation alone inhibits differentiation, trapping cells in a progenitor-like state, it also increases cell death rates leading to an overall reduction in tissue size. Bottom: In the presence of oncogenic RasV12, these progenitor-like cells become refractory to cell death, which drives tumor growth. Additionally, NF-κB/Dorsal activates JNK signaling and enhances the invasiveness of polarity-deficient RasV12/scrib−/− tumors.

Schematics Top: While Toll-NF-κB pathway activation alone inhibits differentiation, trapping cells in a progenitor-like state, it also increases cell death rates leading to an overall reduction in tissue size. Bottom: In the presence of oncogenic RasV12, these progenitor-like cells become refractory to cell death, which drives tumor growth. Additionally, NF-κB/Dorsal activates JNK signaling and enhances the invasiveness of polarity-deficient RasV12/scrib−/− tumors.

#InnateImmunity is a crucial surveillance framework. However, @colombani-lab.bsky.social explores 2 @plosbiology.org studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth 🧪 Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0

11 months ago 5 3 0 0
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Intestinal Tissue Mechanics Regulate Angiogenesis and Stem Cell Proliferation via Vascular Piezo The vasculature is a prominent component of developmental and adult tissue microenvironments. How, tissue specific characteristics and environmental states influence vascular biology and function, rem...

Happy to share the preprint of our latest work on gut/vascular interactions in flies and mice! www.biorxiv.org/cgi/content/...

1 year ago 8 4 0 0
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Great lab! Great Xmas lunch!

1 year ago 8 0 0 0
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1 year ago 5 0 0 0
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Welcome to the #EDRC2025 account of the 28th European Drosophila Conference which will take place in Alicante from the 25th to the 28th of September 2025! Stay tuned for the upcoming news!

1 year ago 15 11 0 2

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1 year ago 2 0 1 0

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1 year ago 0 0 0 0

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1 year ago 1 0 0 0
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Pvf1-PvR-mediated crosstalk between the trachea and the gut guides intestinal stem cell migration to promote gut regeneration. bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Excited to share our last preprint describing how intestinal stem cell migration promotes gut regeneration!
www.biorxiv.org/content/10.1...

1 year ago 5 3 0 0
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The small intestine adapt its size according to nutrient intake Resizing of the intestine is a highly conserved strategy employed by a wide range of organisms to cope with fluctuation in nutrient availability. Nevertheless, very little is known about the mechanism...

The small intestine adapt its size according to nutrient intake 👇👇
www1.bio.ku.dk/english/news...

2 years ago 5 2 0 0
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Exciting beginning of the year with the accepted version of our activins paper "Drosophila activins adapt gut size to food intake and promote regenerative growth"
rdcu.be/du9K2

2 years ago 3 0 0 0
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Wishing everyone happy holidays! Thank you to the lab for creating a lovely environment!

Here is the latest photo of us celebrating at our recent Christmas lunch!

2 years ago 1 0 0 0