3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer - Communications Biology A 3D high-throughput screen in type I collagen is established to score drug efficacy by colony morphology, identifying three antibiotics that re-epithelialize colorectal cancer colonies and enhance ch...

What if flipping CRC colony morphology could boost chemo?

New @nature.com paper shows azithromycin drives re-epithelialization in 3D collagen and sensitizes to irinotecan. Validations used #GelCount to objectively count 3D colonies.

#CancerResearch #3DCulture

www.nature.com/articles/s42...

Check our tech note on culturing & differentiating mESCs in PeptiMatrix™ peptide hydrogels!

From stemness to neurons, it's a flexible 3D platform for real results.

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#stemcells #3Dculture #biotech #animalfree #hydrogels

Development of human salivary gland cell lines for modeling radiation-induced damage in three-dimensional spheroid cultures - Apr 30, 2025
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#3Dculture #xerostomia #cancerresearch #oncsky #oncology #tissueengineering #openaccess

Congrats @jennhammel.bsky.social and Jenny Munson on this great work! This model of the human lymph node stroma under fluid flow is super interesting and will be useful to answer many future questions. Always a pleasure to collaborate with you. #immunoengineering #LymphNodes #3Dculture

Delighted to move over to Bluesky. We are a #CellPolarity
lab using #3Dculture to study how cells collectively move in cancer @cruk-si.bsky.social. Give us a follow if you're into 3D culture, phosphoinositides or metastasis. Strong supporter of equality and helping pull folks up the ladder.