#CotM: at the start of the year we look at the end of a cell's life: the #caspase cascade activates #apoptosis:
e.g. Casp-6 autocleaves or is cleaved by Casp-3,-8,-10 & cleaves Casp-2,-8,-10 and affects the apoptosome (incl. Casp-9):@PDBeurope #3p45

ebi.ac.uk/complexportal/…