Matricellular protein SMOC2 safeguards tubular integrity in acute kidney injury via integrin β3-dependent inhibition of CCND1-CDK4/6 axis - Molecular Biomedicine Tubular injury during acute kidney injury (AKI) is a major determinant of chronic kidney disease (CKD) progression, yet the molecular mechanisms underlying tubular protection remain incompletely under...

#Research
Matricellular protein #SMOC2 safeguards tubular integrity in acute #kidney injury via integrin β3-dependent inhibition of #CCND1-#CDK4/6 axis doi.org/10.1186/s435...
Researchers from University of Montreal

#SMOC2 #AcuteTubularInjury #RenalFibrosis #CellCycleArrest