🩺 If your blood pressure is stubbornly high despite doing everything "right," ask your doctor about primary aldosteronism — a hormonal condition that's way more common than most doctors realize and almost never gets checked.

#BloodPressure #HormoneHealth #Aldosteronism

Spectrum of Aldosteronism and Cardiovascular Outcomes This cohort study investigates the association between spectrum of primary aldosteronism and incident cardiovascular disease in older adults.

Relación aldosterona:renina elevada se asocia con un riesgo elevado de fibrilación auricular e ictus isquémico en adultos mayores #aldosteronism #CVD jamanetwork.com/journals/jam...

The February issue is now online!

👉Read our latest articles! onlinelibrary.wiley.com/toc/13652796/2026/299/2

#aldosteronism #cryoglobulinemia #colitis #dementia #dermatomyositis #JAK #cardiovascular #COVID19 #SARSCoV2 #mRNA #vaccination #liver #psoriasis

New review to read! Emerging methods for subtype differentiation in primary #aldosteronism.

➡️ From the Think Tank meeting: Primary aldosteronism, an emerging disease - Improving management and long-term outcomes.

🔗 doi.org/10.1111/joim.70055

Post-treatment renin status and cardiovascular, renal, and mortality outcomes in medically treated primary aldosteronism: a systematic review and meta-analysis The association between unsuppressed renin following medical therapy for primary aldosteronism and reduced risk of cardiovascular events and all-cause mortality suggests that renin normalisation might...

The association between unsuppressed #renin following medical therapy for primary #aldosteronism and reduced risk of #cardiovascular events and all-cause mortality suggests that renin normalisation might serve as a therapeutic target thelancet.com/journals/lan...
#CVD

#MedSky #EndoSky #CardioSky

#MedNews - The risk for cardiovascular events and all-cause mortality is lower among patients with primary #aldosteronism who have unsuppressed versus suppressed renin after mineral corticoid receptor agonist use.

Full story 👉 buff.ly/n6EXtw5

#EndoSky

Primary aldosteronism and plasma renin targets Over the past two decades there have been tremendous advancements in the understanding of both the prevalence and the clinical significance of primary aldosteronism. Where previously only the most ext...

Linked Comment by Kevin S Fay & Debbie L Cohen:
Primary #aldosteronism and plasma #renin targets www.thelancet.com/journals/lan...

#MedSky #EndoSky #CardioSky

The association between unsuppressed #renin following medical therapy for primary #aldosteronism and reduced risk of cardiovascular events and all-cause mortality suggests that renin normalisation might serve as a therapeutic target www.thelancet.com/journals/lan...
#primary #aldosteronism

#EndoSky

9/12 Change 2: A new recommendation to screen more patients for primary #aldosteronism.

This condition, which causes hypertension, is "more common than previously recognized".

Staggering stat: It's present in up to 20% of patients with resistant hypertension.

Our findings reinforce the clinical importance of post-treatment #renin as a biomarker to assess the efficacy of medical treatment for #primary #aldosteronism, particularly for #cardiovascular protection thelancet.com/journals/lan...
#secondary #hypertension #CVD

#MedSky #EndoSky #CardioSky

Primary aldosteronism and plasma renin targets Over the past two decades there have been tremendous advancements in the understanding of both the prevalence and the clinical significance of primary aldosteronism. Where previously only the most ext...

Linked Comment by Kevin S Fay & Debbie L Cohen:
Primary #aldosteronism and plasma #renin targets www.thelancet.com/journals/lan...

#MedSky #EndoSky #CardioSky

Post-treatment renin status and cardiovascular, renal, and mortality outcomes in medically treated primary aldosteronism: a systematic review and meta-analysis The association between unsuppressed renin following medical therapy for primary aldosteronism and reduced risk of cardiovascular events and all-cause mortality suggests that renin normalisation might...

The association between unsuppressed #renin following medical therapy for primary #aldosteronism and reduced risk of #cardiovascular events and all-cause #mortality suggests that renin normalisation might serve as a therapeutic target www.thelancet.com/journals/lan...

#MedSky #EndpoSky #CardioSky

Optimal Treatment of Primary Aldosteronism: Can We Compare Apples to Oranges? Primary aldosteronism (PA) is an endocrine disorder characterized by inappropriate and excessive aldosterone production.1 PA is a prevalent cause of elevat

Comparing Management strategies for Primary Aldosteronism: Is it 🍎 versus 🍊 ?

Commentary academic.oup.com/ajh/article-...

based on
academic.oup.com/ajh/article-...

#Hypertension #Aldosteronism

Recent Advances in Adrenal Ablation for Primary Aldosteronism Primary aldosteronism (PA) is characterized by autonomous renin-independent aldosterone production from one or both adrenal glands which leads to inappropr

Advances in Adrenal Ablation for Aldosteronism

Commentary academic.oup.com/ajh/article-...

Based on
academic.oup.com/ajh/article-...
and
academic.oup.com/ajh/article-...

#Aldosteronism #Hypertension

Plasmacytoid Dendritic Cell Content Is Associated With Plasma Aldosterone Concentration in Patients With Primary Aldosteronism AbstractBACKGROUND. Inflammation plays a pivotal role in blood pressure regulation. Current data reflect the important role of T cells in primary hypertens

Plasmacytoid Dendritic Cell Content Is Associated With Plasma Aldosterone Concentration in Patients With Primary Aldosteronism

🔗 academic.oup.com/ajh/article/... 🔒

#Aldosteronism #Hypertension

Comparative Outcomes of Adrenalectomy, Mineralocorticoid Receptor Antagonist, and Percutaneous Adrenal Ablation for Primary Aldosteronism: A Systematic Review and Network Meta-Analysis AbstractBACKGROUND. Percutaneous adrenal ablation (PAA) is an effective and safe therapy for treating patients with primary aldosteronism (PA). However, it

Comparative Outcomes of Adrenalectomy, Mineralocorticoid Receptor Antagonist, and Percutaneous Adrenal Ablation for Primary Aldosteronism: A Systematic Review and Network Meta-Analysis

🔗 academic.oup.com/ajh/article/... 🔒

#Aldosteronism #Hypertension

A Comparative Study of the Clinical Efficacy of Superselective Adrenal Artery Embolization for Patients with Primary Aldosteronism AbstractBACKGROUND. Superselective adrenal artery embolization (SAAE) is a potential treatment option for patients with primary aldosteronism (PA).METHODS.

A Comparative Study of the Clinical Efficacy of Superselective Adrenal Artery Embolization for Patients with Primary Aldosteronism

🔗 academic.oup.com/ajh/article/... 🔒

#Aldosteronism #Hypertension

Long-term Efficacy and Safety of Unilateral Adrenal Artery Embolization in Patients with Idiopathic Hyperaldosteronism: A 24-month Cohort Study AbstractBACKGROUND. Adrenal artery embolization (AAE) has been shown to reduce blood pressure (BP) and correct biochemical abnormalities in patients with i

Long-term Efficacy and Safety of Unilateral Adrenal Artery Embolization in Patients with Idiopathic Hyperaldosteronism: A 24-month Cohort Study

🔗 academic.oup.com/ajh/article/... 🔒

#Aldosteronism #Hypertension

Endocrine grand rounds: Dr Joanne Lin, 2nd yr fellow, presented on primary #aldosteronism diagnosed in pregnancy. Typically Aldo and PRA rise in pregnancy. May make diagnosis harder. Key point: Can use eplerenone safely. @cudeptofmedicine.bsky.social

A global real-world study assessing total time to adrenalectomy in primary aldosteronism by Charmaine Ter et al

EJE Volume 193, Issue 1, July 2025
Open access article 👉 doi.org/10.1093/ejen...

#endocrinology #adrenalectomy #aldosteronism

Clinical Practice Guidelines Mobile App The refreshed design for our Clinical Practice Guidelines App puts point-of-care tools at your fingertips like never before. Take advantage of an improved user interface, updated navigation, and new w...

Our mobile app is your source to access all of our Clinical Practice Guidelines, including the latest updates from #ENDO2025. Primary #Aldosteronism and Preexisting #Diabetes in #Pregnancy will be available at your fingertips when you download the app: bit.ly/2NxV5VK
#EndoSky #endocrinology

Subclinical Primary Aldosteronism and Major Adverse Cardiovascular Events: A Longitudinal Population-Based Cohort Study | Circulation BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting evid...

Independientemente de la presión arterial, el aldosteronismo primario subclínico se asocia con un riesgo elevado de eventos CV adversos mayores #aldosteronism #MACE www.ahajournals.org/doi/full/10....

Confirmatory Testing for Primary Aldosteronism: A Study of Diagnostic Test Accuracy: Annals of Internal Medicine: Vol 0, No 0 Background: Confirmatory testing to verify the diagnosis of primary aldosteronism (PA) in patients who have an abnormal screening result is of uncertain benefit. Objective: To perform a blinded assess...

Prueba de supresión salina en posición sentada para evaluar a pacientes con sospecha de aldosteronismo primario se asocia con una alta tasa de falsos negativos, y confiar en ella puede conducir a oportunidades perdidas para la intervención #aldosteronism #accuracy www.acpjournals.org/doi/10.7326/...

Study questions value of SSST confirmatory testing in primary aldosteronism Confirming a diagnosis of primary aldosteronism with the seated saline suppression test may misinform treatment decisions due to its high false negative rate.

#MedNews - Confirming a diagnosis of primary #aldosteronism with the seated saline suppression test may misinform treatment decisions due to its high false negative rate.

Full story 👉 buff.ly/PmfRqn4

#EndoSky #MedSky

Time to Drop Confirmatory Testing for Primary Aldosteronism? The extra test didn't affect treatment outcomes, study suggests

"Confirmatory testing may be a barrier at best and misleading at worst." -- Alexander Leung, MD, MPH, of @ucalgary.bsky.social, discussing confirmatory testing to verify a primary #aldosteronism diagnosis.
www.medpagetoday.com/endocrinolog...

Confirmatory Testing for Primary Aldosteronism: A Study of Diagnostic Test Accuracy: Annals of Internal Medicine: Vol 0, No 0 Background: Confirmatory testing to verify the diagnosis of primary aldosteronism (PA) in patients who have an abnormal screening result is of uncertain benefit. Objective: To perform a blinded assess...

Prueba de supresión salina en posición sentada en pacientes con aldosteronismo primario se asocia con una alta tasa de falsos negativos, y confiar en ella puede conducir a perder oportunidades para la intervención #aldosteronism #SSST www.acpjournals.org/doi/10.7326/...

Confirmatory Testing for Primary Aldosteronism: A Study of Diagnostic Test Accuracy: Annals of Internal Medicine: Vol 0, No 0 Background: Confirmatory testing to verify the diagnosis of primary aldosteronism (PA) in patients who have an abnormal screening result is of uncertain benefit. Objective: To perform a blinded assess...

In the @annalsofim.bsky.social

www.acpjournals.org/doi/10.7326/... from @ucalgarymed.bsky.social team

Saline suppression test not useful in confirming primary #aldosteronism - go straight to AVS if planning Sx (and ramp up MRA to target renin if Medical management)

#NephSky #EndoSky

Impact of primary aldosteronism on calcium phosphate homeostasis. Results from the SPAIN-ALDO - PubMed HPT is a frequent condition in patients with PA and S-HPT is the most common etiology. Patients with HPT have a higher prevalence of atrial fibrillation and hypokalemia and a more severe PA than…

Impact of primary aldosteronism on calcium phosphate homeostasis. Results from the SPAIN-ALDO pubmed.ncbi.nlm.nih.gov/40252188/ #produccionhuil #aldosteronism

Oral Sodium Loading Test Is More Sensitive Than Seated Saline Infusion Test to Confirm Overt Primary Aldosteronism AbstractContext. Primary aldosteronism (PA), a frequent but underdiagnosed cause of hypertension, is associated with a significant burden of cardiovascular

Oral sodium loading test is more sensitive than seated saline infusion test to confirm overt primary #aldosteronism: featured article in #JES. #OpenAccess
#adrenal #diagnosis #aldosterone @endocrinesociety.bsky.social
doi.org/10.1210/jend...