Gut primes pathogenic T cells responsible for neuroinflammation in multiple sclerosis – BioNews Central Researchers identify the role of gut-derived cells in antigen presentation as a key initiator of autoimmune neuroinflammation. ...

Researchers identify the role of #gut -derived cells in #AntigenPresentation as a key initiator of #autoimmune #neuroinflammation.
#MultipleSclerosis #AutoimmuneDisease

HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors.
Adhikari, Santosh et al.
Paper
Details
#Immunotherapy #AntigenPresentation #CancerResearch

graphical abstract

New work from our group: a model of MHC-II antigen exchange on hour–day timescales shows that susceptibility to the exchange catalyst HLA-DM is proportional to the peptide–MHC-II off-rate.

Link to the publication:
www.sciencedirect.com/science/arti...

#AntigenPresentation #MHCII #Immunology

Hugo, a DPhil student in our department, created a brain teaser about #immunopeptidomics. Can you help us solve it? #AntigenPresentation #Immunology #OxfordOpenDoors

Rational Vaccine Development- Borrow Group Our research seeks to inform the rational design of effective prophylactic and therapeutic approaches to combat HIV-1 infection and target blood cancers; and to understand basic principles of immune f...

📢 This week’s #CIOseminar: Professor Persephone Borrow will present the latest research updates from her group! #Vaccines #HIV #CancerResearch #AntigenPresentation 💉🦠🔬

🗓️ Thursday 10 April
🕐 13:00
📍 NDMRB Seminar Room

www.immonc.ox.ac.uk/research-gro...

3/4 We highlight that the conversion of cancer cells to APCs by transcription-factor mediated reprogramming promotes antitumor immunity. You can read the full paper here:
#Antigenpresentation #cancerimmunotherapy #reprogramming

Good things come in threes - our last line of research concentrate our current translational efforts - Harnessing Dendritic Cell Reprogramming for Cancer Immunotherapy. Learn more at #Reprogramming #Immunotherapy #antigenpresentation #Cancer

New Review: Endogenous TAP-independent MHC-I antigen presentation: not just the ER lumen at #CurrentOpinion in #Immunology
#AntigenPresentation From Margarita del Val's Lab @CBMSO_CSIC_UAM

-->Free download link until March 1, 2020:

cc @ImmunologyNews

cutt.ly/urxii5M

New Review: Endogenous TAP-independent MHC-I antigen presentation: not just the ER lumen at #CurrentOpinion in #Immunology
#AntigenPresentation From Margarita del Val's Lab @CBMSO_CSIC_UAM

-->Free download link until March 1, 2020:

cc @ImmunologyNews

cutt.ly/urxii5M