Unveiling Mtb's Secret Weapon: How a New Toxin Hijacks Protein Synthesis to Drive TB Persistence Tuberculosis (TB), caused by the formidable bacterium Mycobacterium tuberculosis (Mtb), remains a devastating global health crisis, responsible for more deaths annually than any other single infectiou...

The Woychik Lab at Rutgers RWJMS uncover MazF-mt11, a TB toxin that halts protein synthesis by snipping the ribosome’s anti-Shine–Dalgarno sequence—helping M. tuberculosis persist for years. go.njmicrobe.org/TuimNi #Tuberculosis #BacterialPersistence #AntimicrobialTargets

How Staphylococcus aureus Exploits a Host Metabolite to Cause Pneumonia Staphylococcus aureus is a formidable foe in healthcare settings, a leading cause of pneumonia that contributes significantly to illness and death worldwide. This ubiquitous bacterium, a common coloni...

How does S. aureus turn a toxic metabolite into a survival tool? Rutgers-led research shows its enzyme FumC converts fumarate into fuel for growth, biofilm, & virulence—opening doors for new anti-pneumonia drugs. go.njmicrobe.org/8MQv9B #Microbiology #Pathogenesis #StaphAureus #AntimicrobialTargets