Arterial Spin Labeling (ASL) is an MRI technique that uses the water in arterial blood as an endogenous contrast agent to non-invasively evaluate perfusion. ASL is available as a 2D EPI sequence (ASL 2D) and as a 3D GRASE sequence (ASL 3D). Both ASL 2D and ASL 3D include a separate M0 scan and an inline calculation of relative cerebral blood flow (relCBF) maps for a quantitative evaluation of perfusion. ASL 3D can be run with a single TI or multiple TI's. The latter are used for fitting the Buxton model to the inflow curve, providing both relCBF and bolus arrival time BAT maps. Clinical applications of ASL include: - Evaluation of brain tumors - Neurodegenerative diseases such as Alzheimer’s and frontotemporal dementia - Acute stroke and evaluation of Transient Ischemic Cerebral Attack (TIA) - Chronic cerebrovascular disease - Functional evaluation of the brain using BOLD techniques - Pre-interventional planning Figure from: Álvarez-Linera J, Vidorreta M, Padilla RH, Martínez Gálvez L, Pfeuffer J. High-Resolution Perfusion Imaging using 3D Arterial Spin Labeling in the Brain. MAGNETOM Flash. 2024;89(4):22–29.
#ASL is a non-invasive #MRI technique using water in arterial blood to measure perfusion. Available in 2D & 3D, it supports relCBF & BAT mapping. Useful in brain tumors, dementia, stroke & more. Learn more: www.magnetomworld.siemens-healthineers.com/clinical-cor...
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