We’re pleased to highlight a recent study published with us:
TBK1 activity regulates the directionality of axonal transport of signalling endosomes.
#Neuroscience #AxonalTransport #Research
Read the full paper 👉 www.life-science-alliance.org/content/9/4/...

Recently published work lead by the very talented @dvillarroelc.bsky.social. Lots of work has gone in to this and I have enjoyed seeing this story develop over the years. Congrats to all! @jamessleigh.bsky.social @joburrito.bsky.social @frattalab.bsky.social @uclqsion.bsky.social #axonaltransport

Do all #NTFs regulate #MotorNeuron axonal transport in vivo?

Our new preprint shows they do not.

#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.

#AxonalTransport regulation is selective, not universal.

@jamessleigh.bsky.social @uclqsion.bsky.social

Beautiful data from @dvillarroelc.bsky.social showing a key role for TBK1 in #AxonalTransport of signalling endosomes:

www.biorxiv.org/content/10.1...

@uclqsion.bsky.social @mndassoc.bsky.social #ALS #MND

A wonderful collaboration. Congratulations to @nicolbirsa.bsky.social & @beccasimkin.bsky.social and all the co-authors #axonaltransport #FUS #MND #ALS #NMJ

Our new paper in Neurobiology of Aging showing that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:

www.sciencedirect.com/science/arti...

@dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging

Next up in our #polaroidproject, we are highlighting @bscb-official.bsky.social PhD rep @emilyxlucas.bsky.social Emily works on axonal transport.
#biologists100 #AxonalTransport #neuroscience

In our latest pre-print, we show that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:

www.biorxiv.org/content/10.1...

Well done team! @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social et al.

@uclqsion.bsky.social #aging