The Unexpected Ways Vaccines Could Boost Your Health As political leaders question vaccine safety, scientists point to studies that show the shots might have unrelated benefits.

Great article in Wall Street Journal today on the benefits of live vaccines including the #bcgvaccine
www.wsj.com/health/welln...

New insights into decades-old bladder cancer treatment may enhance immunotherapy strategies – BioNews Central Over 30 years after the FDA approved the BCG vaccine as the first cancer immunotherapy for early-stage bladder cancer, researchers are advancing knowledge of its mechanism to potentially enhance immunotherapy effectiveness overall. ...

Over 30 years after the FDA approved the #BCGvaccine as the first #CancerImmunotherapy for early-stage #BladderCancer, researchers are advancing knowledge of its mechanism to potentially enhance #immunotherapy effectiveness overall.
#BladderCancerTreatment

#NationalInfantImmunizationWeek is here! 🎉 Did you know the #BCGvaccine, given at birth, protects against #TB? It's a crucial step in safeguarding infants against this infectious disease, ensuring a healthier start to life. #NIIW #ProtectOurFuture

Interested to learn about potential off-target effects from the #BCGvaccine on the #SARSCoV2 vaccine response? Check out the latest work by @nicolemessina.bsky.social and her team @mcri.bsky.social with whom we collaborated! ⬇️

BCG vaccination of healthcare workers for protection against COVID-19: 12-month outcomes from an international randomised controlled trial Bacille Calmette-Guérin (BCG) vaccine has immunomodulatory effects that may provide protection against unrelated infectious diseases. We aimed to dete…

📚 Our findings, along with our earlier study showing that #BCGvaccine increased risk of symptomatic [but not severe] #COVID-19, suggest that BCG vaccination does not enhance immunity to #SARSCoV2 or COVID-19 vaccines 🌍✨ #IDsky #Immunosky www.sciencedirect.com/science/arti...

Similar Spike IgG and T cell IFN-gamma responses to COVID-19 vaccination in BCG-vaccinated and control participants

💉 After two doses of adenovirus-based or mRNA-based #COVID vaccine, cytokine and adaptive immune responses to #SARSCoV2 were similar between the #BCGvaccine and Control groups indicating that the specific effects of #COVID19 vaccines overcame the immunomodulatory effects of BCG. 💪

Forest plot showing lower cytokine responses to SARS-CoV-2 stimulation in BCG-vaccinated compared to control participants

🔬 Before #COVID-19 vaccination (almost a year after randomisation), healthcare workers who received #BCGVaccine had reduced cytokine responses to #SARSCoV2 compared to controls, indicating BCG-induced immunomodulation.

<em>Clinical & Translational Immunology</em> | ASI Journal | Wiley Online Library Bacille Calmette–Guérin (BCG), the vaccine for tuberculosis, has immunomodulatory effects that may underpin its off-target effects on infectious disease risk and vaccine responses. This study used bl....

I’m excited to share our new study of the off-target effects of #BCGVaccine on response to #SARSCoV2 & #COVID-19 vaccines. We analysed immune responses before & after COVID-19 vaccination in healthcare workers in the #BRACE RCT. 💉🦠 #Immunology #IDsky #Immunosky doi.org/10.1002/cti2...

#BCGvaccine has immunomodulatory effects on #immune responses to #SARSCoV2.
Read the full article detailing these immunological findings from #BRACEtrial @ClinTransImmuno

onlinelibrary.wiley.com/doi/10.1002/...