ADAMTS16 as a causal gene for #BiscupidAorticValve
Targeted Exon seq 304 BAV+301 Ctrl➡️p.H357Q

🐭Adamts16 H355Q/+ in both Tie2+ #EndothelialCell & Isl1+ #SecondHeartField, not Wnt1+ #NeuralCrest, contribute to developmental raphe formation

#CircAHA 2023
www.ahajournals.org/doi/abs/10.1...