🔚 That’s a wrap! What caught your attention in May’s brain barrier research? 🧠✨
#Neuroimmunology #BrainBarriers #Tcells #CNS #Neuroscience #SciComm (11/11)

🧵 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆 𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀 𝗶𝗻 𝗕𝗿𝗮𝗶𝗻 𝗕𝗮𝗿𝗿𝗶𝗲𝗿𝘀 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 🧠🔬
February brought some fascinating discoveries in brain barriers! Glycocalyx erosion with age, unique astrocytes at the brain’s surface, and the amphibian BBB.
Dive in! 👇
#BrainBarriers #Neuroscience #BBB (1/12)

Choroid plexus

🧵 December & January highlights in #BrainBarriers research 🧠🔬
Ending 2024 and beginning 2025, I’ve collected my favourite articles on brain barriers. Meninges, mechanical forces at the BBB, and the choroid plexus too!
Let’s go! 👇
#BBB #Neuroscience #Neuroimmunology (1/12)

A peek at the doodling process to make sense of a study linking #neutrophil priming in the #meninges and behavioural adaptation.

🔗 Read more in Neuron @cellpress.bsky.social : www.cell.com/neuron/abstr...
#BrainBarriers #Neuroimmunology #Meninges #Behaviour

Meningeal neutrophil immune signaling influences behavioral adaptation following threat Wu et al. demonstrate how neutrophils, located within the protective layers of the brain, respond to social threats and modulate psychological processes. This process is governed by testosterone in a context-dependent manner and is executed by neutrophil-mediated meningeal immunity, which impedes threat-related neural activity via IFN-γ-GABAergic signaling axis.

❔Could we target meningeal neutrophils to modulate emotional responses to social threats?
🌟 Exciting implications for understanding and possibly treating emotional dysregulation!
🔗 @cellpress.bsky.social: cell.com/neuron/abstr...
#BrainBarriers #Neuroimmunology (9/12)

Sketch of a graphical abstract for a paper on how meningeal neutrophils influence adaptation to socially cued threats.

🧵 November highlights in #BrainBarriers research 🧠🔬
From ageing to behaviour and from the BBB to the meninges: brain barriers influence key vital functions. Last month’s papers are fascinating—let’s go! 👇
#BBB #Neuroscience #Neuroimmunology (1/12)

🧵 October highlights in #BrainBarriers research 🧠🔬
From immune privilege and lymphatics to skull stem cells and microvessel isolation — exciting findings!
Dive in 🧵👇
#BBB #Neuroscience #NeuroImmunology (1/10)