Phase 4 ENGAGE analysis: Adjunctive #brexpiprazole improved life engagement, depression, anxiety and functioning in adults with MDD, regardless of baseline anxiety severity.

🔗Read more in our current issue: journals.lww.com/psychopharma...

#MDD #depression #anxiety #psychopharmacology

In a new phase 3 randomized trial of adults with #PTSD, fixed-dose #brexpiprazole added to sertraline did not outperform #sertraline plus placebo on CAPS-5 symptom improvement, despite reductions across all groups. No new safety concerns were identified.

🔗Read more: journals.lww.com/psychopharma...

US FDA advisers recommend against Otsuka's PTSD combination treatment The U.S. Food and Drug Administration's panel of independent advisers on Friday voted against the efficacy of Otsuka Pharma's antipsychotic drug in combination with Viatris' antidepressant Zoloft for treating adults with PTSD.

US #FDA advisers recommend against Otsuka's #PTSD combination treatment ( #brexpiprazole [ #Rexulti] and #sertraline)

#psychopharmacology #clinicaltrials

www.reuters.com/business/hea...

youtube.com/shorts/K0fGXXSA8V4?feature=share
PTSD that doesn’t respond to SSRIs? There may finally be something worth trying. Here’s the latest brexpiprazole + sertraline RCT:
#Psychiatrist #PTSD #Psychopharm #Brexpiprazole #Sertraline #RCT #Psychiatry #PTSDtreatment #trauma

Rxulti approved in the European Union for adolescent schizophrenia - PharmaTimes EC extends brexpiprazole indication to include adolescents

#mentalhealth #Rxulti #adolescentschizophrenia #schizophrenia #adolescenceonsetschizophrenia #brexpiprazole #typicaloralantipsychotic #antipsychotic #OtsukaPharmaceuticalEurope #Lundbeck #schizophreniainadolescents #CHMP #CHMPapprovel #EuropeanMedicinesAgency
pharmatimes.com/news/rxulti-...

Brexpiprazole and Sertraline for Posttraumatic Stress Disorder This parallel-design, double-blind, randomized clinical trial investigates if combination treatment with brexpiprazole and sertraline is efficacious, safe, and well tolerated in patients with posttrau...

#Medsky🧪 #pharmasky #Clinicaltrial Is brexpiprazole and sertraline combination ( #brexpiprazole + #sertraline) treatment an efficacious, safe, and well-tolerated treatment for #posttraumaticstressdisorder (PTSD)? @jama.com

jamanetwork.com/journals/jam...

New, from JAMA Psychiatry:

#Brexpiprazole and #Sertraline Combination Treatment in Posttraumatic Stress Disorder: A Phase 3 Randomized Clinical Trial

#PTSD #ClinicalTrial #psychopharmacology

Open Access article, with protocol and SAP as supplemental material

📈 The primary endpoint was achieved after 12weeks, which encourages further research on brexpiprazole.

Check the paper to find out more on #borderline treatment: doi.org/10.1017/neu....

#MentalHealth #BorderlinePersonalityDisorder #Research #Brexpiprazole