Hello from EULAR 2025! 🏛️✨ Ready to explore, connect, and learn in Barcelona. 🌍🔬 #EULAR2025 #BrigantLab #ScienceInBarcelona #osteoarthritis #MedSky #AcademicSky

Hello from EULAR 2025! 🏛️✨ Ready to explore, connect, and learn in Barcelona. 🌍🔬
#EULAR2025 #BrigantLab #ScienceInBarcelona #osteoarthritis #MedSky #AcademicSky

🌟 Inside Brigant Lab : The chondrocytes cells 🌟 Have you ever wondered how aging cells contribute to joint damage? Let’s dive into the science together! 🧠💡 Meet the chondrocytes, the architects of cartilage health, maintaining its structure and function. But in osteoarthritis (OA), their balance is disrupted. These cells start contributing to cartilage breakdown, driving joint degeneration. As they age, chondrocytes lose their ability to repair cartilage and produce proteins that accelerate its destruction—worsening joint damage and fueling the progression of OA. Understanding their role is key to unlocking new treatments. 🧬🦴✨ Image: Chondrocyte cells in 2D culture Want to know more? Stay tuned for more #InsideBrigantLab posts, where we’ll share insights into our research and an exclusive preview of what’s next in our scientific journey. 🔍 #CellularBiology #chondrocyteresearch #osteoarthritis #science #research #ArthritisAwarenessMonth #MolecularMedicine#sciencecommunication#lablife #brigantlab #insidebrigantlab

#InsideBrigantLab How do aging cells drive joint damage?🤔
In osteoarthritis, chondrocytes lose their repair abilities and release proteins that accelerate cartilage breakdown, fueling joint degeneration. 🦴

Stay tuned for more insights ! 💡 #MedSky #AcademicSky #cellularbiology #BrigantLab

💚 May is Arthritis Awareness Month! 💚 Arthritis Awareness Month is a global initiative to raise awareness about the impact of rheumatic and musculoskeletal diseases (RMDs), which affect millions of lives worldwide. 🌍 At Brigantlab, we’re shining a light on osteoarthritis (OA)—a common form of arthritis that impacts joints like the knees, hips, and hands. For those living with OA, chronic pain, stiffness, and reduced mobility are daily challenges.🦵🤲 For over 500 million people, OA means chronic pain, stiffness, and reduced mobility, but together, we can make a difference. 💥 🔬 Our research dives deep into how chondrocytes (the cells in cartilage) respond under pathological conditions. With every discovery, we’re closer to better diagnosis, treatments, and hope for those affected.🧬 Let’s remember: ✅ OA doesn’t discriminate—it can affect anyone, at any age. ✅ It’s life-changing, but through awareness and innovation, we can fight back. ✅ Research is the key to unlocking a better future. Join us this month to raise awareness and support advancements in arthritis research. Together, we can take steps toward a pain-free future! 🔥💚✨ #arthritisawarenessmonth #supportarthritis #EULAR #eularadvocacy #osteoarthritis #osteoarthritsawareness #chondrocyteresearch #scienceforchange #research #brigantlab

May is #ArthritisAwarenessMonth A global initiative to highlight the impact of rheumatic & musculoskeletal diseases. At Brigantlab, we're advancing osteoarthritis research to improve lives. Join us in spreading awareness and hope.💚 #Osteoarthritis #RheumaticDiseases #MedSky #AcademicSky #BrigantLab

🚨 Exciting Research Update! 🚨 We’re thrilled to announce the publication of an important and exciting study in Non-Coding RNA Research where BrigantLab was part ! 🎉 We reveal a strong link between uremic toxin levels and the microRNA miR-223 in chronic kidney disease (CKD)-associated anemia. We demonstrated that the uremic toxin indoxyl sulfate (IS) increases miR-223 expression in both human erythroid cell lines and primary cells. In a cohort of over 500 CKD patients, serum miR-223 levels correlated with IS and other uremic toxins, as well as with markers of endothelial dysfunction and anemia severity. 🧬 Why is this important? These findings position miR-223 as a promising biomarker for monitoring CKD-related anemia and vascular complications—opening the door to more personalized and non-invasive diagnostic strategies. 💡 A huge congratulations to Laurent Metzinger for spearheading this important work, and to all the incredible co-authors: Emma Brisot, Pierre-Marie Leprêtre, Eya Hamza, PhD, MBA, Ophelie Fourdinier, Hakim Ouled-Haddou, Gabriel Choukroun, Ziad Massy, Francis Verbeke, Valérie Metzinger-Le Meuth, and Griet Glorieux! ✨ 🔗 Read the full article here: https://doi.org/10.1016/j.ncrna.2025.04.009 [or link in bio] 📖 Stay tuned for more updates from BrigantLab ! 🚀 #ckd #chronickidneydisease #chronickidneydiseaseawareness #anemia #BiomarkerDiscovery #mir223 #uremictoxins #nephrology #Research #Researchpapers #science #lablife #brigantlab

Proud to be part of this new study on uremic toxins & miR-223 in CKD anemia.
🔗Check it:https://doi.org/10.1016/j.ncrna.2025.04.009

#ckd #nephrology #MedSky #AcademicSky #Science #Research #BrigantLab